메뉴 건너뛰기




Volumn 73, Issue 3, 2012, Pages 331-334

Cardiac safety, drug-induced QT prolongation and torsade de pointes (TdP)

Author keywords

[No Author keywords available]

Indexed keywords

AMIODARONE; DOMPERIDONE; ESCITALOPRAM; KETOCONAZOLE; LEVOFLOXACIN; MOXIFLOXACIN; PLACEBO; TERFENADINE;

EID: 84857019812     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2012.04193.x     Document Type: Editorial
Times cited : (20)

References (27)
  • 1
    • 0013881809 scopus 로고
    • La tachycardie ventriculaire à deux foyers opposés variables
    • Dessertenne F. La tachycardie ventriculaire à deux foyers opposés variables. Arch Mal Coeur Vaiss 1966; 59: 263-72.
    • (1966) Arch Mal Coeur Vaiss , vol.59 , pp. 263-272
    • Dessertenne, F.1
  • 2
    • 84856996248 scopus 로고
    • Syncopal attacks following quinidine administration
    • Allison FG. Syncopal attacks following quinidine administration. Can Med Assoc J 1958; 78: 949-50.
    • (1958) Can Med Assoc J , vol.78 , pp. 949-950
    • Allison, F.G.1
  • 3
    • 1442306232 scopus 로고    scopus 로고
    • Drug-induced prolongation of the QT interval
    • Roden DM. Drug-induced prolongation of the QT interval. N Engl J Med 2004; 350: 1013-22.
    • (2004) N Engl J Med , vol.350 , pp. 1013-1022
    • Roden, D.M.1
  • 4
    • 49549091129 scopus 로고    scopus 로고
    • Editors' view: Drug-induced long QT syndrome and drug development
    • Ritter JM. Editors' view: Drug-induced long QT syndrome and drug development. Br J Clin Pharmacol 2008; 66: 341-4.
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 341-344
    • Ritter, J.M.1
  • 5
    • 49549124256 scopus 로고    scopus 로고
    • L'Association française des centres régionaux de pharmacovigilance (CRPV), McKeigue P. Case ascertainment and estimated incidence of drug-induced long-QT syndrome: study in Southwest France
    • Molokhia M, Pathak A, Lapeyre-Mestre M, Pharm LC, Montastruc JL, L'Association française des centres régionaux de pharmacovigilance (CRPV), McKeigue P. Case ascertainment and estimated incidence of drug-induced long-QT syndrome: study in Southwest France. Br J Clin Pharmacol 2008; 66: 386-95.
    • (2008) Br J Clin Pharmacol , vol.66 , pp. 386-395
    • Molokhia, M.1    Pathak, A.2    Lapeyre-Mestre, M.3    Pharm, L.C.4    Montastruc, J.L.5
  • 8
    • 0024321898 scopus 로고
    • Preliminary report: effects of encainide and flecainide on mortality in a randomised trial of arrhythmia suppression after myocardial infarction
    • The Cardiac Arrhythmia Suppression Trial (CAST) Investigators.
    • The Cardiac Arrhythmia Suppression Trial (CAST) Investigators. Preliminary report: effects of encainide and flecainide on mortality in a randomised trial of arrhythmia suppression after myocardial infarction. N Engl J Med 1989; 321: 406-12.
    • (1989) N Engl J Med , vol.321 , pp. 406-412
  • 10
    • 0027515633 scopus 로고
    • Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs
    • Makkar RR, Fromm BS, Steinman RT, Meissner MD, Lehman MH. Female gender as a risk factor for torsades de pointes associated with cardiovascular drugs. JAMA 1993; 270: 2590-7.
    • (1993) JAMA , vol.270 , pp. 2590-2597
    • Makkar, R.R.1    Fromm, B.S.2    Steinman, R.T.3    Meissner, M.D.4    Lehman, M.H.5
  • 11
    • 80051506719 scopus 로고    scopus 로고
    • Sex steroid hormones and electrocardiographic QT-interval duration: findings from the third National Health and Nutrition Examination Survey and the Multi-Ethnic Study of Atherosclerosis
    • Zhang Y, Ouyang P, Post WS, Dalal D, Vaidya D, Blasco-Colmenares E, Soliman EZ, Tomaselli GF, Guallar E. Sex steroid hormones and electrocardiographic QT-interval duration: findings from the third National Health and Nutrition Examination Survey and the Multi-Ethnic Study of Atherosclerosis. Am J Epidemiol 2011; 174: 403-11.
    • (2011) Am J Epidemiol , vol.174 , pp. 403-411
    • Zhang, Y.1    Ouyang, P.2    Post, W.S.3    Dalal, D.4    Vaidya, D.5    Blasco-Colmenares, E.6    Soliman, E.Z.7    Tomaselli, G.F.8    Guallar, E.9
  • 15
    • 48149091056 scopus 로고    scopus 로고
    • Cellular basis of drug-induced torsades de pointes
    • Roden DM. Cellular basis of drug-induced torsades de pointes. Br J Pharmacol 2008; 154: 1502-7.
    • (2008) Br J Pharmacol , vol.154 , pp. 1502-1507
    • Roden, D.M.1
  • 17
    • 74549216361 scopus 로고    scopus 로고
    • Update on the evaluation of new drug for effects on cardiac repolarization in humans: issues in early drug development
    • Salvi V, Karnad DR, Panicker GK, Kothari S. Update on the evaluation of new drug for effects on cardiac repolarization in humans: issues in early drug development. Br J Pharmacol 2010; 159: 34-48.
    • (2010) Br J Pharmacol , vol.159 , pp. 34-48
    • Salvi, V.1    Karnad, D.R.2    Panicker, G.K.3    Kothari, S.4
  • 19
    • 0037066015 scopus 로고    scopus 로고
    • Unique topographical distribution of M cells underlies re-entrant mechanism of torsade de pointes in the long-QT syndrome
    • Akar FG, Yan GX, Antzlevitch C, Rosenbaum DS. Unique topographical distribution of M cells underlies re-entrant mechanism of torsade de pointes in the long-QT syndrome. Circulation 2002; 105: 1247-53.
    • (2002) Circulation , vol.105 , pp. 1247-1253
    • Akar, F.G.1    Yan, G.X.2    Antzlevitch, C.3    Rosenbaum, D.S.4
  • 21
    • 0034244378 scopus 로고    scopus 로고
    • The potential for QT prolongation and proarrhythmia by non-ant-arrhythmic drugs: clinical and regulatory implications
    • Haverkamp W, Breithardt G, Camm AJ etal. The potential for QT prolongation and proarrhythmia by non-ant-arrhythmic drugs: clinical and regulatory implications. Eur Heart J 2000; 21: 1216-31.
    • (2000) Eur Heart J , vol.21 , pp. 1216-1231
    • Haverkamp, W.1    Breithardt, G.2    Camm, A.J.3
  • 22
    • 0036039326 scopus 로고    scopus 로고
    • The significance of QT interval in drug development
    • Shah RR. The significance of QT interval in drug development. Br J Clin Pharmacol 2002; 54: 188-202.
    • (2002) Br J Clin Pharmacol , vol.54 , pp. 188-202
    • Shah, R.R.1
  • 23
    • 84856982636 scopus 로고    scopus 로고
    • Guidance for Industry. E14 clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs. Available at (last accessed 4 February 2012).
    • Guidance for Industry. E14 clinical evaluation of QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs. Available at (last accessed 4 February 2012).
  • 24
    • 79958756212 scopus 로고    scopus 로고
    • Vanishing clinical psychopharmacology
    • van Gerven J, Cohen A. Vanishing clinical psychopharmacology. Br J Clin Pharmacol 2011; 72: 1-5.
    • (2011) Br J Clin Pharmacol , vol.72 , pp. 1-5
    • van Gerven, J.1    Cohen, A.2
  • 25
    • 84857007189 scopus 로고    scopus 로고
    • Population pharmacokinetics and pharmacodynamics of escitolapram in overdose and the effect of activated charcoal
    • van Gorp F, Duffull S, Hackett LP, Isbister GK. Population pharmacokinetics and pharmacodynamics of escitolapram in overdose and the effect of activated charcoal. Br J Clin Pharmacol 2012; 73: 402-10.
    • (2012) Br J Clin Pharmacol , vol.73 , pp. 402-410
    • van Gorp, F.1    Duffull, S.2    Hackett, L.P.3    Isbister, G.K.4
  • 27
    • 84856995147 scopus 로고    scopus 로고
    • Pharmacokinetic interaction between domperidone and ketokinazole leads to QT prolongation in healthy volunteers: a randomized, placebo-controlled, double-blind, crossover study
    • Boyce MJ, Baisley KJ, Warrington SJ. Pharmacokinetic interaction between domperidone and ketokinazole leads to QT prolongation in healthy volunteers: a randomized, placebo-controlled, double-blind, crossover study. Br J Clin Pharmacol 2012; 73: 411-21.
    • (2012) Br J Clin Pharmacol , vol.73 , pp. 411-421
    • Boyce, M.J.1    Baisley, K.J.2    Warrington, S.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.