Comparison of the effects of levofloxacin on QT/QTc interval assessed in both healthy Japanese and Caucasian subjects

British Journal of Clinical Pharmacology

Volumn 73, Issue 3, 2012, Pages 455-459

  Sugiyama, Atsushi ^a   Nakamura, Yuji ^a   Nishimura, Satomi ^a   Adachi Akahane, Satomi ^a   Kumagai, Yuji ^b   Gayed, Juleen ^c   Naseem, Asif ^c   Ferber, Georg ^c   Taubel, Jorg ^c   Camm, John ^c  

^a TOHO UNIVERSITY   (Japan)

^b KITASATO UNIVERSITY   (Japan)

^c ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cardiac safety; Clinical trial methodology; Electrocardiogram; Ethnic comparison; Levofloxacin; Pharmacology

Indexed keywords

LEVOFLOXACIN;

AREA UNDER THE CURVE; ARTICLE; CAUCASIAN; COMPARATIVE STUDY; CONCENTRATION RESPONSE; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG EFFECT; HUMAN; JAPANESE; MAXIMUM PLASMA CONCENTRATION; POST HOC ANALYSIS; PRIORITY JOURNAL; QT INTERVAL; QT PROLONGATION;

ADULT; AGED; ANTI-BACTERIAL AGENTS; AREA UNDER CURVE; ASIAN CONTINENTAL ANCESTRY GROUP; CLINICAL TRIALS AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEART RATE; HUMANS; MALE; MIDDLE AGED; OFLOXACIN; REGRESSION ANALYSIS; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 84857023527     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2011.04110.x     Document Type: Article

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