Minocycline modulates antigen-specific CTL activity through inactivation of mononuclear phagocytes in patients with HTLV-I associated neurologic disease

Retrovirology

Volumn 9, Issue , 2012, Pages

  Enose Akahata, Yoshimi ^a   Matsuura, Eiji ^a,b   Tanaka, Yuetsu ^c   Oh, Unsong ^a,d   Jacobson, Steven ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b KAGOSHIMA UNIVERSITY   (Japan)

^c UNIVERSITY OF THE RYUKYUS   (Japan)

^d VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CTL; HAM TSP; HTLV I; Minocycline; Monocyte

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 1BETA; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MINOCYCLINE; TAX PROTEIN; TUMOR NECROSIS FACTOR ALPHA; IMMUNOSUPPRESSIVE AGENT; VIRUS ANTIGEN;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DEGRANULATION; DENDRITIC CELL; DISEASE ASSOCIATION; DOWN REGULATION; DRUG MECHANISM; HTLV 1 ASSOCIATED MYELOPATHY; HUMAN; HUMAN CELL; HUMAN T CELL LEUKEMIA VIRUS 1; HUMAN TISSUE; IMMUNOMODULATION; IMMUNOREGULATION; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MONOCYTE; MONONUCLEAR PHAGOCYTE; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPIC VARIATION; PROTEIN EXPRESSION; T LYMPHOCYTE ACTIVATION; TROPICAL SPASTIC PARAPARESIS; VIRUS INACTIVATION; VIRUS INFECTIVITY; CELL CULTURE; CHEMISTRY; CYTOTOXIC T LYMPHOCYTE; DRUG ANTAGONISM; DRUG EFFECT; IMMUNOLOGY; PATHOGENICITY; PHAGOCYTE;

HUMAN T-LYMPHOTROPIC VIRUS 1;

ANTIGENS, CD14; ANTIGENS, VIRAL; CELLS, CULTURED; HUMAN T-LYMPHOTROPIC VIRUS 1; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INTERLEUKIN-1BETA; MINOCYCLINE; PARAPARESIS, TROPICAL SPASTIC; PHAGOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84856979164     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-9-16     Document Type: Article

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