Endocrine-mediated effects of 4,4'-(hexafluoroisopropylidene)diphenol in SD rats, based on a subacute oral toxicity study

Archives of Toxicology

Volumn 86, Issue 1, 2012, Pages 151-157

  Umano, Takaaki ^a   Tanaka, Ryota ^b   Yamasaki, Kanji ^a  

^a CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

^b Biosafety Research Center Foods Drugs and Pesticides   (Japan)

Author keywords

4,4' (Hexafluoroisopropylidene)diphenol; Endocrine; Estrogenic effects; OECD test guideline no 407; Rat

Indexed keywords

4,4' (HEXAFLUOROISOPROPYLIDENE)DIPHENOL; PHENOL DERIVATIVE; THYROXINE; UNCLASSIFIED DRUG;

ACCESSORY SEX GLAND; ACUTE TOXICITY; ADRENAL DISEASE; ADRENAL HYPERTROPHY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASSAY; ATROPHY; BONE MARROW DISEASE; BREAST ATROPHY; CELL ATROPHY; CHEMICAL ANALYSIS; CLASSIFICATION; CONTROLLED STUDY; ENDOCRINE DISEASE; ESTRUS CYCLE; FEMALE; HEMATOPOIESIS; HYPERTROPHY; LARGE INTESTINE DISEASE; LEUKOCYTE COUNT; LEYDIG CELL; MALE; NONHUMAN; ORAL TOXICITY; ORGAN WEIGHT; PRACTICE GUIDELINE; PRIORITY JOURNAL; RAT; SPLEEN DISEASE; THYROXINE BLOOD LEVEL; TOXICITY; WEIGHT REDUCTION; ZONA FASCICULATA;

ADMINISTRATION, ORAL; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; ENDOCRINE DISRUPTORS; ENDOCRINE SYSTEM; ESTRADIOL CONGENERS; ESTROUS CYCLE; FEMALE; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; PHENOLS; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; TOXICITY TESTS, SUBACUTE;

RATTUS;

EID: 84856965665     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0731-0     Document Type: Article

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