Isoeugenol destabilizes IL-8 mRNA expression in THP-1 cells through induction of the negative regulator of mRNA stability tristetraprolin

Archives of Toxicology

Volumn 86, Issue 2, 2012, Pages 239-248

  Galbiati, Valentina ^a   Carne, Alice ^a   Mitjans, Montserrat ^b   Galli, Corrado Lodovico ^a   Marinovich, Marina ^a   Corsini, Emanuela ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Alternative method; Cytokines; Dendritic cells; Hypersensitivity; In vitro toxicology; mRNA stability

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; CHEMICAL COMPOUND; DIETHYLMALEATE; HUR PROTEIN; INTERLEUKIN 8; ISOEUGENOL; MESSENGER RNA; PROPIDIUM IODIDE; SALICYLIC ACID; SUPPRESSOR OF CYTOKINE SIGNALING 3; TRISTETRAPROLIN; UNCLASSIFIED DRUG;

ALLERGENICITY; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL STRAIN; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOTOXICITY; GENE EXPRESSION REGULATION; HALF LIFE TIME; IMMUNOREGULATION; PRIORITY JOURNAL; PROMYELOCYTE; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RNA STABILITY; STAINING; UPREGULATION;

ALLERGENS; CELL LINE; CYTOKINES; DINITROCHLOROBENZENE; EUGENOL; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-8; MONOCYTES; RNA STABILITY; RNA, MESSENGER; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS; TRISTETRAPROLIN;

EID: 84856962404     PISSN: 03405761     EISSN: 14320738     Source Type: Journal    
DOI: 10.1007/s00204-011-0758-2     Document Type: Article

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