Burrowing behavior as an indicator of post-laparotomy pain in mice

Frontiers in Behavioral Neuroscience

Volumn 4, Issue OCT, 2010, Pages

  Jirkof, Paulin ^a   Cesarovic, Nikola ^a   Rettich, Andreas ^a   Nicholls, Flora ^b   Seifert, Burkhardt ^c   Arras, Margarete ^a,b  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Analgesia; Burrowing; C57BL 6J mice; Pain assessment; Post laparotomy pain; Post operative pain; Post surgical pain; Species typical behavior

Indexed keywords

EID: 84856932517     PISSN: 16625153     EISSN: None     Source Type: Journal    
DOI: 10.3389/fnbeh.2010.00165     Document Type: Article

References (29)

1. Adams, N., and Boice, R. (1981). Mouse (Mus) burrows-effects of age, strain, and domestication. Anim. Learn. Behav. 9, 140-144.
2. Arras, M., Rettich, A., Cinelli, P., Kasermann, H. P., and Burki, K. (2007). Assessment of post-laparotomy pain in laboratory mice by telemetric recording of heart rate and heart rate variability. BMC Vet. Res. 3, 16.
3. Baumans, V. (2004). Use of animals in experimental research: an ethical dilemma? Gene Ther. 11(Suppl. 1), S64-S66.
4. Baumans, V. (2005). Science-based assessment of animal welfare: laboratory animals. Rev. Sci. Tech. 24, 503-513.
5. Chapman, C. R., Casey, K. L., Dubner, R., Foley, K. M., Gracely, R. H., and Reading, A. E. (1985). Pain measurement-an overview. Pain 22, 1-31.
6. Cunningham, C., Campion, S., Teeling, J., Felton, L., and Perry, V. H. (2007). The sickness behaviour and CNS inflammatory mediator profile induced by systemic challenge of mice with synthetic double-stranded RNA (poly I:C). Brain Behav. Immun. 21, 490-502.
7. Deacon, R. M. (2006). Burrowing in rodents: a sensitive method for detecting behavioral dysfunction. Nat. Protoc. 1, 118-121.
8. Deacon, R. M. (2009). Burrowing: a sensitive behavioural assay, tested in five species of laboratory rodents. Behav. Brain Res. 200, 128-133.
9. Deacon, R. M., Cholerton, L. L., Talbot, K., Nair-Roberts, R. G., Sanderson, D. J., Romberg, C., Koros, E., Bornemann, K. D., and Rawlins, J. N. (2008). Age-dependent and-independent behavioral deficits in Tg2576 mice. Behav. Brain Res. 189, 126-138.
10. Deacon, R. M., Croucher, A., and Rawlins, J. N. (2002). Hippocampal cytotoxic lesion effects on species-typical behaviours in mice. Behav. Brain Res. 132, 203-213.
11. Deacon, R. M., Penny, C., and Rawlins, J. N. (2003). Effects of medial prefrontal cortex cytotoxic lesions in mice. Behav. Brain Res. 139, 139-155.
12. Deacon, R. M. J., Raley, J. M., Perry, V. H., and Rawlins, J. N. P. (2001). Burrowing into prion disease. Neuroreport 12, 2053-2057.
13. Dudek, B. C., Adams, N., Boice, R., and Abbott, M. E. (1983). Genetic influences on digging behaviors in mice (Mus musculus) in laboratory and seminatural settings. J. Comp. Psychol. 97, 249-259.
14. Gauthier, C., and Griffin, G. (2005). Using animals in research, testing and teaching. Rev. Sci. Tech. 24, 735-745.
15. Hawkins, P. (2002). Recognizing and assessing pain, suffering and distress in laboratory animals: a survey of current practice in the UK with recommendations. Lab. Anim. 36, 378-395.
16. Jourdan, D., Ardid, D., and Eschalier, A. (2001). Automated behavioural analysis in animal pain studies. Pharmacol. Res. 43, 103-110.
17. Kohn, D. F., Martin, T. E., Foley, P. L., Morris, T. H., Swindle, M. M., Vogler, G. A., and Wixson, S. K. (2007). Public statement: guidelines for the assessment and management of pain in rodents and rabbits. J. Am. Assoc. Lab. Anim. Sci. 46, 97-108.
18. Langford, D. J., Bailey, A. L., Chanda, M. L., Clarke, S. E., Drummond, T. E., Echols, S., Glick, S., Ingrao, J., Klassen-Ross, T., Lacroix-Fralish, M. L., Matsumiya, L., Sorge, R. E., Sotocinal, S. G., Tabaka, J. M., Wong, D., van den Maagdenberg, A. M., Ferrari, M. D., Craig, K. D., and Mogil, J. S. (2010). Coding of facial expressions of pain in the laboratory mouse. Nat. Methods 7, 447-449.
19. Le Bars, D., Gozariu, M., and Cadden, S. W. (2001). Animal models of nociception. Pharmacol. Rev. 53, 597-652.
20. Martin, T. J., Buechler, N. L., Kahn, W., Crews, J. C., and Eisenach, J. C. (2004). Effects of laparotomy on spontaneous exploratory activity and conditioned operant responding in the rat: a model for postoperative pain. Anesthesiology 101, 191-203.
21. Mogil, J. S. (2009). Animal models of pain: progress and challenges. Nat. Rev. Neurosci. 10, 283-294.
22. Mogil, J. S., and Crager, S. E. (2004). What should we be measuring in behavioral studies of chronic pain in animals? Pain 112, 12-15.
23. Peterson, N. C. (2004). Assessment of pain scoring. Contemp. Top. Lab. Anim. Sci. 43, 74, 76.
24. Roughan, J. V., Wright-Williams, S. L., and Flecknell, P. A. (2009). Automated analysis of postoperative behaviour: assessment of HomeCageScan as a novel method to rapidly identify pain and analgesic effects in mice. Lab. Anim. 43, 17-26.
25. Sherwin, C. M., Haug, E., Terkelsen, N., and Vadgama, M. (2004). Studies on the motivation for burrowing by laboratory mice. Appl. Anim. Behav. Sci. 88, 343-358.
26. Solberg, L. C., Valdar, W., Gauguier, D., Nunez, G., Taylor, A., Burnett, S., Arboledas-Hita, C., Hernandez-Pliego, P., Davidson, S., Burns, P., Bhattacharya, S., Hough, T., Higgs, D., Klenerman, P., Cookson, W. O., Zhang, Y., Deacon, R. M., Rawlins, J. N., Mott, R., and Flint, J. (2006). A protocol for high-throughput phenotyping, suitable for quantitative trait analysis in mice. Mamm. Genome 17, 129-146.
27. Stasiak, K. L., Maul, D., French, E., Hellyer, P. W., and VandeWoude, S. (2003). Species-specific assessment of pain in laboratory animals. Contemp. Top. Lab. Anim. Sci. 42, 13-20.
28. Teeling, J. L., Felton, L. M., Deacon, R. M., Cunningham, C., Rawlins, J. N., and Perry, V. H. (2007). Sub-pyrogenic systemic inflammation impacts on brain and behavior, independent of cytokines. Brain Behav. Immun. 21, 836-850.
29. van Sluyters, R. C., and Obernier, A. (2004). Guidelines for the care and use of mammals in neuroscience and behavioral research. Contemp. Top. Lab. Anim. Sci. 43, 48-52.