Relationship of increased aurora kinase A gene copy number, prognosis and response to chemotherapy in patients with metastatic colorectal cancer

British Journal of Cancer

Volumn 106, Issue 4, 2012, Pages 748-755

  Dotan, E ^a   Meropol, N J ^b   Zhu, F ^a   Zambito, F ^a   Bove, B ^a   Cai, K Q ^a   Godwin, A K ^c   Golemis, E A ^a   Astsaturov, I ^a   Cohen, S J ^a  

^a FOX CHASE CANCER CENTER   (United States)

^b UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

aurora kinase A; colon cancer; copy number; KRAS mutation

Indexed keywords

AURORA A KINASE; BEVACIZUMAB; CAPECITABINE; CETUXIMAB; FLUOROURACIL; IRINOTECAN; OXALIPLATIN; PANITUMUMAB;

ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER PROGNOSIS; COLORECTAL CANCER; FEMALE; GENE DOSAGE; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; ONCOGENE K RAS; OVERALL SURVIVAL; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; SEQUENCE ANALYSIS; TREATMENT RESPONSE;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; GENE DOSAGE; HUMANS; MALE; MIDDLE AGED; MUTATION; NEOPLASM METASTASIS; PROGNOSIS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; RAS PROTEINS;

EID: 84856912673     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2011.587     Document Type: Article

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