PSGL-1 regulates the migration and proliferation of CD8 + T cells under homeostatic conditions

Journal of Immunology

Volumn 188, Issue 4, 2012, Pages 1638-1646

  Veerman, Krystle M ^a   Carlow, Douglas A ^a   Shanina, Iryna ^a   Priatel, John J ^a,b   Horwitz, Marc S ^a   Ziltener, Hermann J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 15; INTERLEUKIN 2; INTERLEUKIN 4; P SELECTIN GLYCOPROTEIN LIGAND 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4 CD8 RATIO; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CONTROLLED STUDY; HOMEOSTASIS; IMMUNE RESPONSE; LYMPH NODE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; LYMPHOCYTE MIGRATION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTOPENIA; MALE; MEMORY CELL; MOUSE; NONHUMAN; PLEIOTROPY; PRIORITY JOURNAL; SPLEEN; STEADY STATE;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; HOMEOSTASIS; INTERLEUKIN-1; INTERLEUKIN-2; INTERLEUKIN-4; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL;

EID: 84856911533     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1103026     Document Type: Article

References (41)

1. Petrie, H. T., and J. C. Zúñiga-Pflücker. 2007. Zoned out: functional mapping of stromal signaling microenvironments in the thymus. Annu. Rev. Immunol. 25: 649-679. (Pubitemid 46697920)
2. Rosen, S. D. 2004. Ligands for L-selectin: homing, inflammation, and beyond. Annu. Rev. Immunol. 22: 129-156. (Pubitemid 38680420)
3. Arbonés, M. L., D. C. Ord, K. Ley, H. Ratech, C. Maynard-Curry, G. Otten, D. J. Capon, and T. F. Tedder. 1994. Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice. Immunity 1: 247-260.
4. Ley, K., and G. S. Kansas. 2004. Selectins in T-cell recruitment to non-lymphoid tissues and sites of inflammation. Nat. Rev. Immunol. 4: 325-335. (Pubitemid 38649275)
5. Gunn, M. D., K. Tangemann, C. Tam, J. G. Cyster, S. D. Rosen, and L. T. Williams. 1998. A chemokine expressed in lymphoid high endothelial venules promotes the adhesion and chemotaxis of naive T lymphocytes. Proc. Natl. Acad. Sci. USA 95: 258-263. (Pubitemid 28103941)
6. Baekkevold, E. S., T. Yamanaka, R. T. Palframan, H. S. Carlsen, F. P. Reinholt, U. H. von Andrian, P. Brandtzaeg, and G. Haraldsen. 2001. The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitment. J. Exp. Med. 193: 1105-1112.
7. Shamri, R., V. Grabovsky, J. M. Gauguet, S. Feigelson, E. Manevich,W. Kolanus, M. K. Robinson, D. E. Staunton, U. H. von Andrian, and R. Alon. 2005. Lymphocyte arrest requires instantaneous induction of an extended LFA-1 conformation mediated by endothelium-bound chemokines. Nat. Immunol. 6: 497-506. (Pubitemid 41716763)
8. Hordijk, P. L. 2006. Endothelial signalling events during leukocyte transmigration. FEBS J. 273: 4408-4415. (Pubitemid 44401592)
9. Mackay, C. R., W. L. Marston, and L. Dudler. 1990. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J. Exp. Med. 171: 801-817. (Pubitemid 20088983)
10. Luther, S. A., H. L. Tang, P. L. Hyman, A. G. Farr, and J. G. Cyster. 2000. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc. Natl. Acad. Sci. USA 97: 12694-12699.
11. Link, A., T. K. Vogt, S. Favre, M. R. Britschgi, H. Acha-Orbea, B. Hinz, J. G. Cyster, and S. A. Luther. 2007. Fibroblastic reticular cells in lymph nodes regulate the homeostasis of naive T cells. Nat. Immunol. 8: 1255-1265. (Pubitemid 350011765)
12. Jiang, Q., W. Q. Li, F. B. Aiello, R. Mazzucchelli, B. Asefa, A. R. Khaled, and S. K. Durum. 2005. Cell biology of IL-7, a key lymphotrophin. Cytokine Growth Factor Rev. 16: 513-533. (Pubitemid 41022015)
13. Berard, M., K. Brandt, S. Bulfone-Paus, and D. F. Tough. 2003. IL-15 promotes the survival of naive and memory phenotype CD8+ T cells. J. Immunol. 170: 5018-5026. (Pubitemid 36554732)
14. Surh, C. D., and J. Sprent. 2008. Homeostasis of naive and memory T cells. Immunity 29: 848-862.
15. Sprent, J., J. H. Cho, O. Boyman, and C. D. Surh. 2008. T cell homeostasis. Immunol. Cell Biol. 86: 312-319. (Pubitemid 351667989)
16. Cyster, J. G. 2005. Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs. Annu. Rev. Immunol. 23: 127-159. (Pubitemid 40563167)
17. Veerman, K. M., M. J. Williams, K. Uchimura, M. S. Singer, J. S. Merzaban, S. Naus, D. A. Carlow, P. Owen, J. Rivera-Nieves, S. D. Rosen, and H. J. Ziltener. 2007. Interaction of the selectin ligand PSGL-1 with chemokines CCL21 and CCL19 facilitates efficient homing of T cells to secondary lymphoid organs. Nat. Immunol. 8: 532-539. (Pubitemid 46605921)
18. Kisielow, P., H. S. Teh, H. Blüthmann, and H. von Boehmer. 1988. Positive selection of antigen-specific T cells in thymus by restricting MHC molecules. Nature 335: 730-733.
19. Carlow, D. A., M. R. Gold, and H. J. Ziltener. 2009. Lymphocytes in the peritoneum home to the omentum and are activated by resident dendritic cells. J. Immunol. 183: 1155-1165.
20. Schwab, S. R., J. P. Pereira, M. Matloubian, Y. Xu, Y. Huang, and J. G. Cyster. 2005. Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients. Science 309: 1735-1739. (Pubitemid 41285945)
21. Murali-Krishna, K., J. D. Altman, M. Suresh, D. J. Sourdive, A. J. Zajac, J. D. Miller, J. Slansky, and R. Ahmed. 1998. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8: 177-187. (Pubitemid 28123745)
22. Gossens, K., S. Naus, S. Y. Corbel, S. Lin, F. M. Rossi, J. Kast, and H. J. Ziltener. 2009. Thymic progenitor homing and lymphocyte homeostasis are linked via S1P-controlled expression of thymic P-selectin/CCL25. J. Exp. Med. 206: 761-778.
23. Berlin-Rufenach, C., F. Otto, M. Mathies, J. Westermann, M. J. Owen, A. Hamann, and N. Hogg. 1999. Lymphocyte migration in lymphocyte function-associated antigen (LFA)-1-deficient mice. J. Exp. Med. 189: 1467-1478. (Pubitemid 29227533)
24. Lo, C. G., Y. Xu, R. L. Proia, and J. G. Cyster. 2005. Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit. J. Exp. Med. 201: 291-301. (Pubitemid 40189438)
25. Sprent, J., and C. D. Surh. 2003. Cytokines and T cell homeostasis. Immunol. Lett. 85: 145-149. (Pubitemid 36071569)
26. Zhang, X., S. Sun, I. Hwang, D. F. Tough, and J. Sprent. 1998. Potent and selective stimulation of memory-phenotype CD8+ T cells in vivo by IL-15. Immunity 8: 591-599. (Pubitemid 28264750)
27. Cho, J. H., O. Boyman, H. O. Kim, B. Hahm, M. P. Rubinstein, C. Ramsey, D. M. Kim, C. D. Surh, and J. Sprent. 2007. An intense form of homeostatic proliferation of naive CD8+ cells driven by IL-2. J. Exp. Med. 204: 1787-1801. (Pubitemid 47236317)
28. Hidalgo, A., L. A. Weiss, and P. S. Frenette. 2002. Functional selectin ligands mediating human CD34(+) cell interactions with bone marrow endothelium are enhanced postnatally. J. Clin. Invest. 110: 559-569. (Pubitemid 34919710)
29. Rossi, F. M., S. Y. Corbel, J. S. Merzaban, D. A. Carlow, K. Gossens, J. Duenas, L. So, L. Yi, and H. J. Ziltener. 2005. Recruitment of adult thymic progenitors is regulated by P-selectin and its ligand PSGL-1. Nat. Immunol. 6: 626-634. (Pubitemid 41710734)
30. Yang, J., T. Hirata, K. Croce, G. Merrill-Skoloff, B. Tchernychev, E. Williams, R. Flaumenhaft, B. C. Furie, and B. Furie. 1999. Targeted gene disruption demonstrates that P-selectin glycoprotein ligand 1 (PSGL-1) is required for Pselectin- mediated but not E-selectin-mediated neutrophil rolling and migration. J. Exp. Med. 190: 1769-1782. (Pubitemid 30013843)
31. Xia, L., M. Sperandio, T. Yago, J. M. McDaniel, R. D. Cummings, S. Pearson- White, K. Ley, and R. P. McEver. 2002. P-selectin glycoprotein ligand-1-deficient mice have impaired leukocyte tethering to E-selectin under flow. J. Clin. Invest. 109: 939-950. (Pubitemid 34275115)
32. Di Rosa, F. 2009. T-lymphocyte interaction with stromal, bone and hematopoietic cells in the bone marrow. Immunol. Cell Biol. 87: 20-29.
33. Mori, S., H. Nakano, K. Aritomi, C. R. Wang, M. D. Gunn, and T. Kakiuchi. 2001. Mice lacking expression of the chemokines CCL21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. J. Exp. Med. 193: 207-218.
34. Matsumoto, M., M. Miyasaka, and T. Hirata. 2009. P-selectin glycoprotein ligand-1 negatively regulates T-cell immune responses. J. Immunol. 183: 7204-7211.
35. Kristensen, N. N., J. P. Christensen, and A. R. Thomsen. 2002. High numbers of IL-2-producing CD8+ T cells during viral infection: correlation with stable memory development. J. Gen. Virol. 83: 2123-2133. (Pubitemid 34993717)
36. Lin, S. J., A. T. Chen, and R. M. Welsh. 2008. Immune system derived from homeostatic proliferation generates normal CD8 T-cell memory but altered repertoires and diminished heterologous immune responses. Blood 112: 680-689.
37. Harp, J. R., M. A. Gilchrist, and T. M. Onami. 2010. Memory T cells are enriched in lymph nodes of selectin-ligand-deficient mice. J. Immunol. 185: 5751-5761.
38. Urzainqui, A., G. Martínez del Hoyo, A. Lamana, H. de la Fuente, O. Barreiro, I. M. Olazabal, P. Martin, M. K. Wild, D. Vestweber, R. González-Amaro, and F. Sánchez-Madrid. 2007. Functional role of P-selectin glycoprotein ligand 1/Pselectin interaction in the generation of tolerogenic dendritic cells. J. Immunol. 179: 7457-7465.
39. Förster, R., A. C. Davalos-Misslitz, and A. Rot. 2008. CCR7 and its ligands: balancing immunity and tolerance. Nat. Rev. Immunol. 8: 362-371. (Pubitemid 351595218)
40. Ziegler, E., M. Oberbarnscheidt, S. Bulfone-Paus, R. Förster, U. Kunzendorf, and S. Krautwald. 2007. CCR7 signaling inhibits T cell proliferation. J. Immunol. 179: 6485-6493.
41. Junt, T., E. Scandella, R. Förster, P. Krebs, S. Krautwald, M. Lipp, H. Hengartner, and B. Ludewig. 2004. Impact of CCR7 on priming and distribution of antiviral effector and memory CTL. J. Immunol. 173: 6684-6693. (Pubitemid 39541053)