Mucosal and Peripheral Lin - HLA-DR + CD11c/123 - CD13 + CD14 - mononuclear cells are preferentially infected during acute simian immunodeficiency virus infection

Journal of Virology

Volumn 86, Issue 2, 2012, Pages 1069-1078

  Moore, Andrew C ^a   Bixler, Sandra L ^a   Lewis, Mark G ^b   Verthelyi, Daniela ^c   Mattapallil, Joseph J ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

^b BIOQUAL INC   (United States)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; CD14 ANTIGEN; CHEMOKINE RECEPTOR CCR5; GLYCOPROTEIN P 15095; HLA DR ANTIGEN; MICROSOMAL AMINOPEPTIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ARTICLE; BLOOD ANALYSIS; CD4+ T LYMPHOCYTE; CELL LEVEL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; JEJUNUM MUCOSA; MACROPHAGE; MEMORY T LYMPHOCYTE; MONOCYTE; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RETROVIRUS INFECTION; SIMIAN IMMUNODEFICIENCY VIRUS; SIMIAN IMMUNODEFICIENCY VIRUS INFECTION; TISSUE DISTRIBUTION; VIRUS LOAD;

ANIMALS; ANTIGENS, CD11; ANTIGENS, CD13; ANTIGENS, CD14; DISEASE MODELS, ANIMAL; HIV; HIV INFECTIONS; HLA-DR ANTIGENS; HUMANS; LEUKOCYTES, MONONUCLEAR; MACACA MULATTA; MUCOUS MEMBRANE; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS;

SIMIAN IMMUNODEFICIENCY VIRUS;

EID: 84856904491     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.06372-11     Document Type: Article

References (62)

1. Alexaki A, Liu Y, Wigdahl B. 2008. Cellular reservoirs of HIV-1 and their role in viral persistence. Curr. HIV Res. 6:388-400.
2. Bannert N, Schenten D, Craig S, Sodroski J. 2000. The level of CD4 expression limits infection of primary rhesus monkey macrophages by a T-tropic simian immunodeficiency virus and macrophagetropic human immunodeficiency viruses. J. Virol. 74:10984-10993.
3. Berger EA. 1997. HIV entry and tropism: the chemokine receptor connection. AIDS 11(Suppl. A):S3-S16.
4. + T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract. J. Exp. Med. 200:749-759.
5. Burdo TH, et al. 2010. Increased monocyte turnover from bone marrow correlates with severity of SIV encephalitis and CD163 levels in plasma. PLoS Pathog. 6:e1000842.
6. Chun TW, et al. 1997. Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387:183-188.
7. Clayton F, et al. 1992. Rectal mucosal pathology varies with human immunodeficiency virus antigen content and disease stage. Gastroenterology 103:919-933.
8. Depboylu C, Eiden LE, Weihe E. 2007. Increased APOBEC3G expression is associated with extensive G-to-A hypermutation in viral DNA in rhesus macaque brain during lentiviral infection. J. Neuropathol. Exp. Neurol. 66:901-912.
9. Doms RW, Peiper SC. 1997. Unwelcomed guests with master keys: how HIV uses chemokine receptors for cellular entry. Virology 235:179-190.
10. Eberly MD, et al. 2009. Increased IL-15 production is associated with higher susceptibility of memory CD4 T cells to simian immunodeficiency virus during acute infection. J. Immunol. 182:1439-1448.
11. + monocyte subset is more permissive to infection and preferentially harbors HIV-1 in vivo. J. Immunol. 178: 6581-6589.
12. Embretson J, et al. 1993. Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS. Nature 362:359-362.
13. + peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection. J. Neurovirol. 7:528-541.
14. + T-cell depletion in gut lymphoid tissue during primary human immunodeficiency virus type 1 infection and substantial delay in restoration following highly active antiretroviral therapy. J. Virol. 77:11708-11717.
15. Hasegawa A, et al. 2009. The level of monocyte turnover predicts disease progression in the macaque model of AIDS. Blood 114:2917-2925.
16. + T cells by a highly pathogenic simian immunodeficiency virus/HIV type 1 chimera (SHIV): implications for HIV-1 infections of humans. Proc. Natl. Acad. Sci. U. S. A. 98:658-663.
17. + monocyte subset preferentially harbors HIV-1 and is expanded in pregnant Malawian women with Plasmodium falciparum malaria and HIV-1 infection. J. Infect. Dis. 196:38-42.
18. + memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection. Mucosal Immunol. 2:439-449.
19. Kedzierska K, Crowe SM. 2002. The role of monocytes and macrophages in the pathogenesis of HIV-1 infection. Curr. Med. Chem. 9:1893-1903.
20. Kelly J, et al. 2008. Human macrophages support persistent transcription from unintegrated HIV-1 DNA. Virology 372:300-312.
21. Kewenig S, et al. 1999. Rapid mucosal CD4(_) T-cell depletion and enteropathy in simian immunodeficiency virus-infected rhesus macaques. Gastroenterology 116:1115-1123.
22. Kim WK, et al. 2010. Monocyte heterogeneity underlying phenotypic changes in monocytes according to SIV disease stage. J. Leukoc. Biol. 87:557-567.
23. Kitagawa M, Lackner AA, Martfeld DJ, Gardner MB, Dandekar S. 1991. Simian immunodeficiency virus infection of macaque bone marrow macrophages correlates with disease progression in vivo. Am. J. Pathol. 138: 921-930.
24. Koenig S, et al. 1986. Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy. Science 233:1089-1093.
25. Kozak SL, Kuhmann SE, Platt EJ, Kabat D. 1999. Roles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1. J. Biol. Chem. 274:23499-23507.
26. Kozak SL, et al. 1997. CD4, CXCR-4, and CCR-5 dependencies for infections by primary patient and laboratory-adapted isolates of human immunodeficiency virus type 1. J. Virol. 71:873-882.
27. Kuroda MJ. 2010. Macrophages: do they impact AIDS progression more than CD4 T cells? J. Leukoc. Biol. 87:569-573.
28. Kuwata T, et al. 2007. Contribution of monocytes to viral replication in macaques during acute infection with simian immunodeficiency virus. AIDS Res. Hum. Retroviruses 23:372-380.
29. Lewin SR, et al. 1998. HIV-1 DNA and mRNA concentrations are similar in peripheral blood monocytes and alveolar macrophages in HIV-1-infected individuals. AIDS 12:719-727.
30. Lewin SR, et al. 1996. Surface CD4 is critical to in vitro HIV infection of human alveolar macrophages. AIDS Res. Hum. Retroviruses 12:877-883.
31. + T cells. Nature 434:1148-1152.
32. + lymphocytes in control of simian immunodeficiency virus infection and resistance to rechallenge after transient early antiretroviral treatment. J. Virol. 75:10187-10199.
33. Luciw PA, Pratt-Lowe E, Shaw KE, Levy JA, Cheng-Mayer C. 1995. Persistent infection of rhesus macaques with T-cell-line-tropic and macrophage-tropic clones of simian/human immunodeficiency viruses (SHIV). Proc. Natl. Acad. Sci. U. S. A. 92:7490-7494.
34. Mandell CP, Jain NC, Miller CJ, Dandekar S. 1995. Bone marrow monocyte/macrophages are an early cellular target of pathogenic and nonpathogenic isolates of simian immunodeficiency virus (SIVmac) in rhesus macaques. Lab. Invest. 72:323-333.
35. + T cells in multiple tissues during acute SIV infection. Nature 434: 1093-1097.
36. McElrath MJ, Pruett JE, Cohn ZA. 1989. Mononuclear phagocytes of blood and bone marrow: comparative roles as viral reservoirs in human immunodeficiency virus type 1 infections. Proc. Natl. Acad. Sci. U. S. A. 86:675-679.
37. + T lymphocytes from effector sites in the gastrointestinal tract. J. Exp. Med. 200:761-770.
38. Miller CJ. 1998. Localization of simian immunodeficiency virus-infected cells in the genital tract of male and female rhesus macaques. J. Reprod. Immunol. 41:331-339.
39. Miller CJ, Shattock RJ. 2003. Target cells in vaginal HIV transmission. Microbes Infect. 5:59-67.
40. Montaner LJ, et al. 2006. Advances in macrophage and dendritic cell biology in HIV-1 infection stress key understudied areas in infection, pathogenesis, and analysis of viral reservoirs. J. Leukoc. Biol. 80:961-964.
41. Montaner LJ, et al. 1993. Interleukin 13 inhibits human immunodeficiency virus type 1 production in primary blood-derived human macrophages in vitro. J. Exp. Med. 178:743-747.
42. Orenstein JM, Fox C, Wahl SM. 1997. Macrophages as a source of HIV during opportunistic infections. Science 276:1857-1861.
43. Peng G, et al. 2007. Myeloid differentiation and susceptibility to HIV-1 are linked to APOBEC3 expression. Blood 110:393-400.
44. Pesenti E, et al. 1999. Role of CD4 and CCR5 levels in the susceptibility of primary macrophages to infection by CCR5-dependent HIV type 1 isolates. AIDS Res. Hum. Retroviruses 15:983-987.
45. Platt EJ, Wehrly K, Kuhmann SE, Chesebro B, Kabat D. 1998. Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1. J. Virol. 72: 2855-2864.
46. Rich EA, Chen IS, Zack JA, Leonard ML, O'Brien WA. 1992. Increased susceptibility of differentiated mononuclear phagocytes to productive infection with human immunodeficiency virus-1 (HIV-1). J. Clin. Invest. 89:176-183.
47. + T cells recognize and inhibit SIV replication in infected macrophages early after infection. Proc. Natl. Acad. Sci. U. S. A. 106:9791-9796.
48. + T cells from HIV controllers. Blood 118:955-964.
49. Schmittgen TD, Livak KJ. 2008. Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3:1101-1108.
50. Schrofelbauer B, Senger T, Manning G, Landau NR. 2006. Mutational alteration of human immunodeficiency virus type 1 Vif allows for functional interaction with nonhuman primate APOBEC3G. J. Virol. 80: 5984-5991.
51. Schuitemaker H, et al. 1992. Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages. J. Clin. Invest. 89:1154-1160.
52. Shen R, et al. 2011. Stromal down-regulation of macrophage CD4/CCR5 expression and NF-kappaB activation mediates HIV-1 non-permissiveness in intestinal macrophages. PLoS Pathog. 7:e1002060.
53. + T-cell depletion at all stages of simian immunodeficiency virus infection compared to peripheral lymphocytes. J. Virol. 72:6646-6656.
54. Smith PD, Fox CH, Masur H, Winter HS, Alling DW. 1994. Quantitative analysis of mononuclear cells expressing human immunodeficiency virus type 1 RNA in esophageal mucosa. J. Exp. Med. 180:1541-1546.
55. Smith PD, Meng G, Shaw GM, Li L. 1997. Infection of gastrointestinal tract macrophages by HIV-1. J. Leukoc. Biol. 62:72-77.
56. Sui Y, et al. 2010. Innate and adaptive immune correlates of vaccine and adjuvant-induced control of mucosal transmission of SIV in macaques. Proc. Natl. Acad. Sci. U. S. A. 107:9843-9848.
57. Tajima Y, et al. 2009. Use of a modified alpha-N-acetylgalactosaminidase in the development of enzyme replacement therapy for Fabry disease. Am. J. Hum. Genet. 85:569-580.
58. + T cell depletion and viral replication in SIV infection. Science 280:427-431.
59. Williams KC, Burdo TH. 2009. HIV and SIV infection: the role of cellular restriction and immune responses in viral replication and pathogenesis. Apmis 117:400-412.
60. Williams KC, et al. 2001. Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS. J. Exp. Med. 193:905-915.
61. Yu Q, et al. 2004. APOBEC3B and APOBEC3C are potent inhibitors of simian immunodeficiency virus replication. J. Biol. Chem. 279: 53379-53386.
62. Zhu T. 2002. HIV-1 in peripheral blood monocytes: an underrated viral source. J. Antimicrob. Chemother. 50:309-311.