Increased APOBEC3G expression is associated with extensive G-to-A hypermutation in viral DNA in rhesus macaque brain during lentiviral infection

Journal of Neuropathology and Experimental Neurology

Volumn 66, Issue 10, 2007, Pages 901-912

  Depboylu, Candan ^a   Eiden, Lee E ^b   Weihe, Eberhard ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

Antiretroviral treatment; Hypermutations; Inflammatory infiltrates; Intrinsic immunity; Macrophages; Neuro AIDS; T lymphocytes

Indexed keywords

APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; VIRUS DNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN; BRAIN DAMAGE; CONTROLLED STUDY; DNA ISOLATION; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNE DEFICIENCY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; LENTIVIRINAE; MONKEY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS INFECTION;

ADENOSINE; ANIMALS; CYTIDINE DEAMINASE; DNA, VIRAL; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, VIRAL; GUANINE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MACACA MULATTA; MUTATION; RNA PROBES; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; UP-REGULATION;

EID: 34948846536     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1097/nen.0b013e3181567a59     Document Type: Article

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