Replacing immunoassays with tryptic digestion-peptide immunoaffinity enrichment and LC-MS/MS

Bioanalysis

Volumn 4, Issue 3, 2012, Pages 281-290

  Becker, Jessica O ^a   Hoofnagle, Andrew N ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; MONOCLONAL ANTIBODY; PEPTIDE; PEPTIDE ANTIBODY; POLYCLONAL ANTIBODY; TRYPSIN;

ANALYTIC METHOD; ANTIBODY AFFINITY; ANTIBODY PRODUCTION; CALIBRATOR; CLINICAL PROTOCOL; COMPUTER ANALYSIS; COMPUTER MODEL; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOASSAY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; NONHUMAN; PEPTIDE ANALYSIS; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; PROTEIN CLEAVAGE; PROTEIN CROSS LINKING; PROTEIN DETERMINATION; PROTEIN METABOLISM; PROTEIN PURIFICATION; QUALITY CONTROL; QUANTITATIVE ASSAY; REVIEW; SENSITIVITY ANALYSIS; SOLID PHASE EXTRACTION; STABLE ISOTOPE STANDARDS AND CAPTURE BY ANTIPEPTIDE ANTIBODY; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ANTIBODIES; CHROMATOGRAPHY, AFFINITY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; IMMUNOASSAY; PEPTIDES; PROTEINS; TANDEM MASS SPECTROMETRY; TRYPSIN;

EID: 84856900264     PISSN: 17576180     EISSN: 17576199     Source Type: Journal    
DOI: 10.4155/bio.11.319     Document Type: Review

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