Oxidation of Met 1606 in von Willebrand factor is a risk factor for thrombotic and septic complications in chronic renal failure

Biochemical Journal

Volumn 442, Issue 2, 2012, Pages 423-432

  De Filippis, Vincenzo ^a   Lancellotti, Stefano ^b   Maset, Fabio ^a   Spolaore, Barbara ^a   Pozzi, Nicola ^a,e   Gambaro, Giovanni ^c   Oggianu, Laura ^b,d   Calo, Lorenzo A ^a   De Cristofaro, Raimondo ^b  

^a UNIVERSITY OF PADOVA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

^d ROMA TRE UNIVERSITY   (Italy)

^e SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

A disintegrin and metalloproteinase with thrombospondin motifs 13 (ADAMTS 13); Chronic renal failure; Mass spectrometry; Oxidative stress sepsis; Von Willebrand factor (vWF)

Indexed keywords

METHIONINE SULFOXIDE; VON WILLEBRAND FACTOR CLEAVING PROTEINASE; ADAM PROTEIN; ADAMTS13 PROTEIN, HUMAN; ADHESIN; METHIONINE; PEPTIDE FRAGMENT; VON WILLEBRAND FACTOR;

ADULT; ARTICLE; CHRONIC KIDNEY FAILURE; CLINICAL ARTICLE; CONTROLLED STUDY; HEMODIALYSIS; HOMEOSTASIS; HUMAN; INFLAMMATION; MEGAKARYOCYTE; MICROVASCULAR ENDOTHELIAL CELL; MOLECULAR WEIGHT; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN PURIFICATION; RISK FACTOR; SEPSIS; THROMBOSIS; VASCULAR ENDOTHELIUM; AMINO ACID SEQUENCE; BLOOD; CASE CONTROL STUDY; CHEMISTRY; FEMALE; GENETICS; MALE; METABOLISM; MIDDLE AGED; MOLECULAR GENETICS; OXIDATION REDUCTION REACTION; PROTEIN MULTIMERIZATION; RENAL REPLACEMENT THERAPY; THROMBOCYTE ACTIVATION;

BACTERIA (MICROORGANISMS);

ADAM PROTEINS; ADHESINS, BACTERIAL; ADULT; AMINO ACID SEQUENCE; CASE-CONTROL STUDIES; FEMALE; HUMANS; KIDNEY FAILURE, CHRONIC; MALE; METHIONINE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MOLECULAR WEIGHT; OXIDATION-REDUCTION; PEPTIDE FRAGMENTS; PLATELET ACTIVATION; PROTEIN MULTIMERIZATION; RENAL DIALYSIS; RISK FACTORS; SEPSIS; THROMBOSIS; VON WILLEBRAND FACTOR;

EID: 84856888752     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20111798     Document Type: Article

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