Protein phosphatase 1α interacting proteins in the human brain

OMICS A Journal of Integrative Biology

Volumn 16, Issue 1-2, 2012, Pages 3-17

  Esteves, Sara L C ^a   Domingues, Sara C ^a   Da Cruz E Silva, Odete A B ^a   Fardilha, Margarida ^a   Da Cruz E Silva, Edgar F ^a  

^a UNIVERSITY OF AVEIRO   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; PHOSPHOPROTEIN PHOSPHATASE 1; PLASMID DNA;

BRAIN; CONFERENCE PAPER; DRUG TARGETING; ENZYME ACTIVITY; HUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; TWO HYBRID SYSTEM; YEAST;

BRAIN; DATABASES, GENETIC; GENE LIBRARY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; PROTEIN INTERACTION MAPPING; PROTEIN PHOSPHATASE 1; TWO-HYBRID SYSTEM TECHNIQUES;

PIPS;

EID: 84856865411     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2011.0041     Document Type: Conference Paper

References (74)

1. Allen, P.B., Ouimet, C.C., and Greengard, P. (1997a). Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc Natl Acad Sci USA 94, 9956-9961. (Pubitemid 27408172)
2. Allen, P.B., Ouimet, C.C., and Greengard, P. (1997b). Spinophilin, a novel protein phosphatase 1 binding protein localized to dendritic spines. Proc Natl Acad Sci USA 94, 9956-9961. (Pubitemid 27408172)
3. Armstrong, C.G., Browne, G.J., Cohen, P., and Cohen, P.T. (1997). PPP1R6, a novel member of the family of glycogentargetting subunits of protein phosphatase 1. FEBS Lett 418, 210-214. (Pubitemid 27514448)
4. Auluck, P.K., Caraveo, G., and Lindquist, S. (2010). a-Synuclein: Membrane interactions and toxicity in Parkinson's disease. Annu Rev Cell Dev Biol 26, 211-233.
5. Ayllon, V., Cayla, X., Garcia, A., Fleischer, A., and Rebollo, A. (2002). The anti-apoptotic molecules Bcl-xL and Bcl-w target protein phosphatase 1alpha to Bad. Eur J Immunol 32, 1847-1855. (Pubitemid 34822814)
6. Bennett, D., and Alphey, L. (2002). PP1 binds Sara and negatively regulates Dpp signaling in Drosophila melanogaster. Nat Genet 31, 419-423. (Pubitemid 35154454)
7. Bennett, D., Lyulcheva, E., Alphey, L., and Hawcroft, G. (2006). Towards a comprehensive analysis of the protein phosphatase 1 interactome in Drosophila. J Mol Biol 364, 196-212. (Pubitemid 44647255)
8. Bollen, M. (2001). Combinatorial control of protein phosphatase- 1. Trends Biochem Sci 26, 426-431.
9. Boyce, M., Bryant, K.F., Jousse, C., Long, K., Harding, H.P., Scheuner, D., et al. (2005). A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress. Science 307, 935-939. (Pubitemid 40229232)
10. Brush, M.H., Weiser, D.C., and Shenolikar, S. (2003). Growth arrest and DNA damage-inducible protein GADD34 targets protein phosphatase 1 alpha to the endoplasmic reticulum and promotes dephosphorylation of the alpha subunit of eukaryotic translation initiation factor 2. Mol Cell Biol 23, 1292-1303. (Pubitemid 36177038)
11. Brush, M.H., Guardiola, A., Connor, J.H., Yao, T.P., and Shenolikar, S. (2004). Deactylase inhibitors disrupt cellular complexes containing protein phosphatases and deacetylases. J Biol Chem 279, 7685-7691. (Pubitemid 38294650)
12. Ceulemans, H., and Bollen, M. (2004). Functional diversity of protein phosphatase-1, a cellular economizer and reset button. Physiol Rev 84, 1-39. (Pubitemid 38049874)
13. Ceulemans, H., Stalmans, W., and Bollen, M. (2002). Regulatordriven functional diversification of protein phosphatase-1 in eukaryotic evolution. Bioessays 24, 371-381. (Pubitemid 34305692)
14. Chen, C.Y., Lai, N.S., Yang, J.J., Huang, H.L., Hung, W.C., Li, C., et al. (2010). FLJ23654 encodes a heart protein phosphatase 1- binding protein (Hepp1). Biochem Biophys Res Commun 391, 698-702.
15. Cohen, P. (2001). The role of protein phosphorylation in human health and disease. The Sir Hans Krebs Medal Lecture. Eur J Biochem 268, 5001-5010. (Pubitemid 32955552)
16. Cohen, P.T. (2002). Protein phosphatase 1-targeted in many directions. J Cell Sci 115, 241-256. (Pubitemid 34145174)
17. Colland, F., Jacq, X., Trouplin, V., Mougin, C., Groizeleau, C., Hamburger, A., et al. (2004). Functional proteomics mapping of a human signaling pathway. Genome Res 14, 1324-1332. (Pubitemid 39029229)
18. Da Cruz Silva, E.F., Da Cruz Silva, O.A., Zaia, C.T., and Greengard, P. (1995a) Inhibition of protein phosphatase 1 stimulates secretion of Alzheimer amyloid precursor protein. Mol Med. 1, 535-541.
19. Da Cruz Silva, E.F., Fox, C.A., Ouimet, C.C., Gustafson, E., Watson, S.J., and Greengard, P. (1995b) Differential expression of protein phosphatase 1 isoforms in mammalian brain. J Neurosci. 15, 3375-3389.
20. Doherty, M.J., Young, P.R., and Cohen, P.T. (1996). Amino acid sequence of a novel protein phosphatase 1 binding protein (R5) which is related to the liver- and muscle-specific glycogen binding subunits of protein phosphatase 1. FEBS Lett 399, 339-343. (Pubitemid 26426878)
21. Egloff, M.P., Johnson, D.F., Moorhead, G., Cohen, P.T., Cohen, P., and Barford, D. (1997). Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1. EMBO J 16, 1876-1887. (Pubitemid 27170949)
22. Engelender, S., Kaminsky, Z., Guo, X., Sharp, A.H., Amaravi, R.K., Kleiderlein, J.J., et al. (1999). Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet 22, 110-114. (Pubitemid 29214817)
23. Esteves, S.L. (2008). Characterization of Human Brain Protein Phosphatase 1 Alpha Interacting Proteins Using the Yeast Two- Hybrid System. Aveiro: Biology Department. University of Aveiro.
24. Fardilha, M., Esteves, S.L., Korrodi-Gregorio, L., Da Cruz Silva, O.A., and Da Cruz Silva, F.F. (2010). The physiological relevance of protein phosphatase 1 and its interacting proteins to health and disease. Curr Med Chem 17, 3996-4017.
25. Fardilha, M., Esteves, S.L., Korrodi-Gregorio, L., Pelech, S., Da Cruz, E.S.O.A., and Da Cruz, E.S.E. (2011a). Protein phosphatase 1 complexes modulate sperm motility and present novel targets for male infertility. Mol Hum Reprod 17, 453-456.
26. Fardilha, M., Esteves, S.L., Korrodi-Gregorio, L., Vintem, A.P., Domingues, S.C., Rebelo, S., et al. (2011b). Identification of the human testis protein phosphatase 1 interactome. Biochem Pharmacol [Epub ahead of print].
27. Fardilha, M., Wu, W., Sa, R., Fidalgo, S., Sousa, C., Mota, C., et al. (2004). Alternatively spliced protein variants as potential therapeutic targets for male infertility and contraception. Ann N Y Acad Sci. 1030, 468-478. (Pubitemid 40378948)
28. Feng, J., Yan, Z., Ferreira, A., Tomizawa, K., Liauw, J.A., Zhuo, M., et al. (2000). Spinophilin regulates the formation and function of dendritic spines. Proc Natl Acad Sci USA 97, 9287-9292. (Pubitemid 30626711)
29. Fields, S., and Song, O. (1989). A novel genetic system to detect protein-protein interactions. Nature 340, 245-246. (Pubitemid 19171591)
30. Flores-Delgado, G., Liu, C.W., Sposto, R., and Berndt, N. (2007). A limited screen for protein interactions reveals new roles for protein phosphatase 1 in cell cycle control and apoptosis. J Proteome Res 6, 1165-1175. (Pubitemid 46480481)
31. Gagnon, K.B., England, R., Diehl, L., and Delpire, E. (2007). Apoptosis-associated tyrosine kinase scaffolding of protein phosphatase 1 and SPAK reveals a novel pathway for Na-K- 2C1 cotransporter regulation. Am J Physiol Cell Physiol 292, C1809-C1815. (Pubitemid 47080541)
32. Gandy, S., and Greengard, P. (1994). Regulated cleavage of the Alzheimer amyloid precursor protein: Molecular and cellular basis. Biochimie 76, 300-303. (Pubitemid 24295549)
33. Gibbons, J.A., Weiser, D.C., and Shenolikar, S. (2005). Importance of a surface hydrophobic pocket on protein phosphatase- 1 catalytic subunit in recognizing cellular regulators. J Biol Chem 280, 15903-15911. (Pubitemid 40616713)
34. Graff, J., Koshibu, K., Jouvenceau, A., Dutar, P., and Mansuy, I.M. (2010). Protein phosphatase 1-dependent transcriptional programs for long-term memory and plasticity. Learn Mem 17, 355-363.
35. Helps, N.R., Barker, H.M., Elledge, S.J., and Cohen, P.T. (1995). Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53. FEBS Lett 377, 295-300. (Pubitemid 26025716)
36. Helps, N.R., Luo, X., Barker, H.M., and Cohen, P.T. (2000a). NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1. Biochem J 349, 509-518. (Pubitemid 30465786)
37. Helps, N.R., Luo, X., Barker, H.M., and Cohen, P.T. (2000b). NIMA-related kinase 2 (Nek2), a cell-cycle-regulated protein kinase localized to centrosomes, is complexed to protein phosphatase 1. Biochem J 349, 509-518. (Pubitemid 30465786)
38. Hendrickx, A., Beullens, M., Ceulemans, H., Den Abt, T., Van Eynde, A., Nicolaescu, E., et al. (2009). Docking motif-guided mapping of the interactome of protein phosphatase-1. Chem Biol 16, 365-371.
39. Hrabchak, C., and Varmuza, S. (2004). Identification of the spermatogenic zip protein Spz1 as a putative protein phosphatase-1 (PP1) regulatory protein that specifically binds the PP1cgamma2 splice variant in mouse testis. J Biol Chem 279, 37079-37086. (Pubitemid 39129058)
40. Huang, F.L., and Glinsmann, W.H. (1976). Separation and characterization of two phosphorylase phosphatase inhibitors from rabbit skeletal muscle. Eur J Biochem 70, 419-426.
41. Hurley, T.D., Yang, J., Zhang, L., Goodwin, K.D., Zou, Q., Cortese, M., et al. (2007). Structural basis for regulation of protein phosphatase 1 by inhibitor-2. J Biol Chem 282, 28874-28883. (Pubitemid 47606030)
42. Jousse, C., Oyadomari, S., Novoa, I., Lu, P., Zhang, Y., Harding, H.P., et al. (2003). Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells. J Cell Biol 163, 767-775. (Pubitemid 37517884)
43. Kao, S.C., Chen, C.Y., Wang, S.L., Yang, J.J., Hung, W.C., Chen, Y.C., et al. (2007). Identification of phostensin, a PP1 F-actin cytoskeleton targeting subunit. Biochem Biophys Res Commun 356, 594-598.
44. Kepp, O., Galluzzi, L., Giordanetto, F., Tesniere, A., Vitale, I., Martins, I., et al. (2009). Disruption of the PP1/GADD34 complex induces calreticulin exposure. Cell Cycle 8, 3971-3977.
45. Koshibu, K., Graff, J., Beullens, M., Heitz, F.D., Berchtold, D., Russig, H., et al. (2009). Protein phosphatase 1 regulates the histone code for long-term memory. J Neurosci 29, 13079-13089.
46. Lin, Q., Buckler, E.S.T., Muse, S.V., and Walker, J.C. (1999). Molecular evolution of type 1 serine/threonine protein phosphatases. Mol Phylogenet Evol 12, 57-66. (Pubitemid 129499288)
47. Lin, T.H., Tsai, P.C., Liu, H.T., Chen, Y.C., Wang, L.H., Hsieh, F.K., et al. (2005). Characterization of the protein phosphatase 1-binding motifs of inhibitor-2 and DARPP-32 by surface plasmon resonance. J Biochem (Tokyo) 138, 697-700.
48. Llorian, M., Beullens, M., Andres, I., Ortiz, J.M., and Bollen, M. (2004). SIPP1, a novel pre-mRNA splicing factor and interactor of protein phosphatase-1. Biochem J 378, 229-238. (Pubitemid 38299562)
49. Luo, W., Peterson, A., Garcia, B.A., Coombs, G., Kofahl, B., Heinrich, R., et al. (2007). Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex. EMBO J 26, 1511-1521. (Pubitemid 46480933)
50. Luo, X., Weber, G.A., Zheng, J., Gendelman, H.E., and Ikezu, T. (2003). C1q-calreticulin induced oxidative neurotoxicity: Relevance for the neuropathogenesis of Alzheimer's disease. J Neuroimmunol 135, 62-71. (Pubitemid 36170152)
51. Monshausen, M., Rehbein, M., Richter, D., and Kindler, S. (2002). The RNA-binding protein Staufen from rat brain interacts with protein phosphatase-1. J Neurochem 81, 557-564. (Pubitemid 34809334)
52. Moorhead, G.B., Trinkle-Mulcahy, L., Nimick, M., De Wever, V., Campbell, D.G., Gourlay, R., et al. (2008). Displacement affinity chromatography of protein phosphatase one (PP1) complexes. BMC Biochem 9, 28.
53. Munro, S., Ceulemans, H., Bollen, M., Diplexcito, J., and Cohen, P.T. (2005). A novel glycogen-targeting subunit of protein phosphatase 1 that is regulated by insulin and shows differential tissue distribution in humans and rodents. FEBS J 272, 1478-1489. (Pubitemid 40444936)
54. Neumann, J. (2002). Altered phosphatase activity in heart failure, influence on Ca2 + movement. Basic Res Cardiol 97(Suppl 1), I91-I95.
55. Ouimet, C.C., Da Cruz Silva, E.F., and Greengard, P. (1995). The alpha and gamma 1 isoforms of protein phosphatase 1 are highly and specifically concentrated in dendritic spines. Proc Natl Acad Sci USA 92, 3396-3400.
56. Rehman, A.U., Morell, R.J., Belyantseva, I.A., Khan, S.Y., Boger, E.T., Shahzad, M., et al. (2010). Targeted capture and nextgeneration sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79. Am J Hum Genet 86, 378-388.
57. Ribeiro, C.S., Carneiro, K., Ross, C.A., Menezes, J.R., and Engelender, S. (2002). Synphilin-1 is developmentally localized to synaptic terminals, and its association with synaptic vesicles is modulated by alpha-synuclein. J Biol Chem 277, 23927-23933. (Pubitemid 34952237)
58. Sagara, J., Higuchi, T., Hattori, Y., Moriya, M., Sarvotham, H., Shima, H., et al. (2003). Scapinin, a putative protein phosphatase- 1 regulatory subunit associated with the nuclear nonchromatin structure. J Biol Chem 278, 45611-45619. (Pubitemid 37432703)
59. Santos, M. (2009). Validation of LAP1B as a Novel Protein Phosphatase 1 Regulator. Aveiro: Biology Department, University of Aveiro.
60. Shannon, P., Markiel, A., Ozier, O., Baliga, N.S., Wang, J.T., Ramage, D., et al. (2003). Cytoscape: A software environment for integrated models of biomolecular interaction networks. Genome Res 13, 2498-2504. (Pubitemid 37428274)
61. Shi, W., Sun, C., He, B., Xiong, W., Shi, X., Yao, D., et al. (2004). GADD34-PP1c recruited by Smad7 dephosphorylates TGFbeta type I receptor. J Cell Biol 164, 291-300. (Pubitemid 38133948)
62. Skinner, J.A., and Saltiel, A.R. (2001). Cloning and identification of MYPT3: A prenylatable myosin targetting subunit of protein phosphatase 1. Biochem J 356, 257-267. (Pubitemid 34275728)
63. Sridhar, R., Hanson-Painton, O., and Cooper, D.R. (2000). Protein kinases as therapeutic targets. Pharm Res 17, 1345-1353. (Pubitemid 32109485)
64. Tanuma, N., Kim, S.E., Beullens, M., Tsubaki, Y., Mitsuhashi, S., Nomura, M., et al. (2008). Nuclear inhibitor of protein phosphatase-1 (NIPP1) directs protein phosphatase-1 (PP1) to dephosphorylate the U2 small nuclear ribonucleoprotein particle (snRNP) component, spliceosome-associated protein 155 (Sap155). J Biol Chem 283, 35805-35814.
65. Ten, V.S., Yao, J., Ratner, V., Sosunov, S., Fraser, D.A., Botto, M., et al. (2010). Complement component c1q mediates mitochondria- driven oxidative stress in neonatal hypoxic-ischemic brain injury. J Neurosci 30, 2077-2087.
66. Terrak, M., Kerff, F., Langsetmo, K., Tao, T., and Dominguez, R. (2004). Structural basis of protein phosphatase 1 regulation. Nature 429, 780-784. (Pubitemid 38833131)
67. Tran, H.T., Ulke, A., Morrice, N., Johannes, C.J., and Moorhead, G.B. (2004). Proteomic characterization of protein phosphatase complexes of the mammalian nucleus. Mol Cell Proteomics 3, 257-265. (Pubitemid 38714281)
68. Trinkle-Mulcahy, L., Ajuh, P., Prescott, A., Claverie-Martin, F., Cohen, S., Lamond, A.I., et al. (1999). Nuclear organisation of NIPP1, a regulatory subunit of protein phosphatase 1 that associates with pre-mRNA splicing factors. J Cell Sci 112(Pt 2), 157-168. (Pubitemid 29078350)
69. Trinkle-Mulcahy, L., Andersen, J., Lam, Y.W., Moorhead, G., Mann, M., and Lamond, A.I. (2006). Repo-Man recruits PP1 gamma to chromatin and is essential for cell viability. J Cell Biol 172, 679-692.
70. Ulke-Lemee, A., Trinkle-Mulcahy, L., Chaulk, S., Bernstein, N.K., Morrice, N., Glover, M., et al. (2007). The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G. Biochim Biophys Acta 1774, 1339-1350. (Pubitemid 47484292)
71. Virshup, D.M., and Shenolikar, S. (2009). From promiscuity to precision: Protein phosphatases get a makeover. Mol Cell 33, 537-545.
72. Wakabayashi, K., Engelender, S., Tanaka, Y., Yoshimoto, M., Mori, F., Tsuji, S., et al. (2002). Immunocytochemical localization of synphilin-1, an alpha-synuclein-associated protein, in neurodegenerative disorders. Acta Neuropathol 103, 209-214. (Pubitemid 36075320)
73. Wakabayashi, K., Engelender, S., Yoshimoto, M., Tsuji, S., Ross, C.A., and Takahashi, H. (2000). Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann Neurol 47, 521-523. (Pubitemid 30194611)
74. Wakula, P., Beullens, M., Ceulemans, H., Stalmans, W., and Bollen, M. (2003). Degeneracy and function of the ubiquitous RVXF motif that mediates binding to protein phosphatase-1. J Biol Chem 278, 18817-18823. (Pubitemid 36799263)