SIPP1, a novel pre-mRNa splicing factor and interactor of protein phosphatase-1

Biochemical Journal

Volumn 378, Issue 1, 2004, Pages 229-238

  Llorian, Miriam ^a   Beullens, Monique ^b   Andrés, Isabel ^a   Ortiz, Jose Miguel ^a   Bollen, Mathieu ^b  

^a UNIVERSITY OF CANTABRIA   (Spain)

^b UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

Dephosphorylation; Polyglutamine tract; Protein phosphatase 1 (PP1); SIPP1; Spliceosome; Splicing

Indexed keywords

CATALYSIS; ENZYME INHIBITION; FLUORESCENCE; PROTEINS; SEDIMENTATION;

NUCLEAR LOCALIZATION SIGNALS; PHOSPHORYLATION; SPLICING FACTOR;

RNA;

AMINO ACID; BINDING PROTEIN; CASEIN KINASE I; GREEN FLUORESCENT PROTEIN; PHOSPHOPROTEIN PHOSPHATASE 1; POLYGLUTAMINE TRACT BINDING PROTEIN 1; PROTEIN; PROTEIN NPW38; PROTEIN SIPP1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEPHOSPHORYLATION; EMBRYO; ENZYME ACTIVE SITE; ENZYME INHIBITION; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RNA SPLICING; SEQUENCE TAGGED SITE; SPLICEOSOME; TWO HYBRID SYSTEM;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; HELA CELLS; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEIN PHOSPHATASE; PROTEINS; RNA PRECURSORS; RNA SPLICING; RNA, MESSENGER; SPLICEOSOMES; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 1542314816     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20030950     Document Type: Article

References (42)

1. Bollen, M. (2001) Combinatorial control of protein phosphatase-1. Trends Biochem. Sci. 26, 426-431
2. Bollen, M. and Beullens, M. (2002) Signaling by protein phosphatases in the nucleus. Trends Cell Biol. 12, 138-145
3. Ceulemans, H., Stalmans, W. and Bollen M. (2002) Regulator-driven functional diversification of protein phosphatase-1 in eukaryotic evolution. BioEssays 24, 371-381
4. Cohen, P. T. W. (2002) Protein phosphatase 1 - targeted in many directions. J. Cell Sci. 115, 241-256
5. Egloff, M.-P., Johnson, D. F., Moorhead, G., Cohen, P. T. W., Cohen, P. and Barford, D. (1997) Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phophatase 1. EMBO J. 16, 1876-1887
6. Zhao, S. and Lee, E. Y. C. (1997) Targeting of the catalytic subunit of protein phosphatase-1 to the glycolytic enzyme phosphofructokinase. J. Biol. Chem. 272, 28368-28372
7. Wakula, P., Beullens, M., Ceulemans, H., Stalmans, W. and Bollen, M. (2003) Degeneracy and function of the ubiquitous RVXF-motif that mediates binding to protein phosphatase-1. J. Biol. Chem. 278, 18817-18823
8. Stralfors, P., Hiraga, A. and Cohen, P. (1985) The protein phosphatases involved in cellular regulation: purification and characterisation of the glycogen-bound form of protein phosphatase-1 from rabbit skeletal muscle. Eur. J. Biochem. 149, 295-303
9. Beullens, M., Van Eynde, A., Stalmans, W. and Bollen, M. (1992) The isolation of novel inhibitory polypeptides of protein phosphatase 1 from bovine thymus nuclei. J. Biol. Chem. 267, 16538-16544
10. Alessi, D., MacDougall, L. K., Sola, M. M., Ikebe, M. and Cohen, P. (1992) The control of protein phosphatase-1 by targetting subunits: the major myosin phosphatase in avian smooth muscle is a novel form of protein phosphatase-1. Eur. J. Biochem. 210, 1023-1035
11. Campos, M., Fadden, P., Alms, G., Qian, Z. and Haystead, T. A. J. (1996) Identification of protein phosphatase-1-binding proteins by microcystin-biotin affinity chromatography. J. Biol. Chem. 271, 28478-28484
12. Walsh, E. P., Lamont, D. J., Beattie, K. A. and Stark, M. J. (2002) Novel interactions of Saccharomyces cerevisiae type 1 protein phosphatase identified by single-step affinity purification and mass spectrometry. Biochemistry 41, 2409-2420
13. Ceulemans, H., Vulsteke, V., De Maeyer, M., Tatchell, K., Stalmans, W. and Bollen, M. (2002) Binding of the concave surface of the Sds22 superhelix to the α4/α5/α6-triangle of protein phosphatase-1. J. Biol. Chem. 277, 47331-47337
14. Helps, N. R., Barker, H. M., Elledge, S. J. and Cohen, P. T. W. (1995) Protein phosphatase 1 interacts with p53BP2, a protein which binds to the tumour suppressor p53. FEBS Lett. 377, 295-300
15. Hartshorne, D. J. and Hirano, K. (1999) Interactions of protein phosphatase type 1, with a focus on myosin phosphatase. Mol. Cell. Biochem. 190, 79-84
16. Ayllón, V., Cayla, X., García, A., Roncal, F., Fernández, R., Albar, J. P., Martínez-A., C. and Rebollo, A. J. (2001) Bcl-2 targets protein phosphatase 1α to Bad. J. Immunol. 166, 7345-7352
17. Rudenko, A., Bennett, D. and Alphey, L. (2003) Trithorax interacts with type 1 serine/threonine protein phosphatase in Drosophila. EMBO Rep. 4, 59-63
18. Komuro, A., Saeki, M. and Kato, S. (1999) Association of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginine. J. Biol. Chem. 274, 36513-36519
19. Craggs, G., Finan, P. M., Lawson, D., Wingfield, J., Perera, T., Gadher, S., Totty, N. F. and Kellie, S. (2001) A nuclear SH3 domain-binding protein that colocalizes with mRNA splicing factors and intermediate filament-containing perinuclear networks. J. Biol. Chem. 276, 30552-30560
20. DeGuzman, A. and Lee, E. Y. C. (1988) Preparation of low-molecular- weight forms of rabbit muscle protein phosphatase. Methods Enzymol. 159, 356-368
21. Baker, S. H., Frederick, D. L., Bloecher, A. and Tatchell, K. (1997) Alanine-scanning mutagenesis of protein phosphatase type 1 in the yeast Saccharomyces cerevisiae. Genetics 145, 615-626
22. Louvet, O., Doignon, F. and Crouzet, M. (1997) Stable DNA-binding yeast vector allowing high-bait expression for use in the two-hybrid system. BioTechniques 23, 816-818, 820
23. Crespo, P., Xu, N., Daniotti, J. L., Troppmair, J., Rapp, U. R. and Gutkind, J. S. (1994) Signaling through transforming G protein-coupled receptors in NIH 3T3 cells involves c-Raf activation: evidence for a protein kinase C-independent pathway J. Biol. Chem. 269, 21103-21109
24. Beullens, M., Stalmans, W. and Bollen, M. (1998) The isolation of novel inhibitory polypeptides of protein phosphatase 1 from bovine thymus nuclei. Methods Mol. Biol. 93, 145-155
25. Beullens, M. and Bollen, M. (2002) The protein phosphatase-1 regulator NIPP1 is also a splicing factor involved in a late step of spliceosome assembly. J. Biol. Chem. 277, 19885-19860
26. Egloff, M.-P., Cohen, P. T. W., Reinemer, P. and Barford, D. (1995) Crystal structure of the catalytic subunit of human protein phosphatase 1 and its complex with tungstate. J. Mol. Biol. 254, 942-959
27. Goldberg, J., Huang, H., Kwon, Y., Greengard, P., Nairn, A. C. and Kuriyan, J. (1995) Three-dimensional structure of the catalytic subunit of protein serine/threonine phosphatase-1. Nature (London) 376, 745-753
28. Misteli, T. and Spector, D. L. (1997) Protein phosphorylation and the nuclear organization of pre-mRNA splicing. Trends Cell Biol. 7, 135-138
29. Mermoud, J. E., Cohen, P. T. and Lamond, A. I. (1994) Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism. EMBO J. 13, 5679-5688
30. Katayama, H., Zhou, H., Li, Q., Tatsuka, M. and Sen, S. (2001) Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle. J. Biol. Chem. 276, 46219-46224
31. Connor, J. H., Weiser, D. C., Li, S., Hallenbeck, J. M. and Shenolikar, S. (2001) Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1. Mol. Cell. Biol. 21, 6841-6850
32. Reference deleted
33. Reference deleted
34. Waragai, M., Junn, E., Kajikawa, M., Takeuchi, S., Kanzawa, I., Shibata, M., Mouradian, M. M. and Okazawa, H. (2000) PQBP-1/Npw38, a nuclear protein binding to the polyglutamine tract, interacts with U5-15kD/dim1p via the carboxyl-terminal domain. Biochem. Biophys. Res. Commun. 273, 592-595
35. Zhang, Y-Z., Lindblom, T., Chang, A., Sudol, M., Sluder, A. E. and Golemis, E. A. (2000) Evidence that dim1 associates with proteins involved in pre-mRNA splicing and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1. Gene 257, 33-43
36. Zhou, Z., Licklider, L. J., Gygi, S. P. and Reed, R. (2002) Comprehensive proteomic analysis of the human spliceosome. Nature (London) 419, 182-185
37. Reference deleted
38. Macias, M. J., Wiesner, S. and Sudol, M. (2002) WW and SH3 domains, two different scaffolds to recognize proline-rich ligands. FEBS Lett. 513, 30-37
39. Okazawa, H., Rich, T., Chang, A., Lin, X., Waragai, M., Kajikawa, M., Enokido, Y., Komuro, A., Kato, S., Shibata, M. et al. (2002) Interaction between mutant ataxin-1 and PQBP-1 affects transcription and cell death. Neuron 34, 701-713
40. Washington, K., Ammosova, T., Beullens, M., Jerebtsova, M., Kumar, A., Bollen, M. and Nekai, S. (2002) Protein phosphatase-1 dephosphorylates the C-terminal domain of RNA polymerase-II. J. Biol. Chem. 277, 40442-40448
41. Boudrez, A., Beullens, M., Groenen, P., Van Eynde, A., Vulsteke, V., Jagiello, I., Murray, M., Krainer, A. R., Stalmans, W. and Bollen, M. (2000) NIPP1-mediated interaction of protein phosphatase-1 with CDC5L, a regulator of pre-mRNA splicing and mitotic entry. J. Biol. Chem. 275, 25411-25417
42. Boudrez, A., Beullens, M., Waelkens, E., Stalmans, W. and Bollen, M. (2002) Phosphorylation-dependent interaction between the splicing factors SAP155 and NIPP1. J. Biol. Chem. 277, 31834-31841