Oligoclonal antibody targeting ghrelin increases energy expenditure and reduces food intake in fasted mice

Molecular Pharmaceutics

Volumn 9, Issue 2, 2012, Pages 281-289

  Zakhari, Joseph S ^a,b,c   Zorrilla, Eric P ^a   Zhou, Bin ^a,b   Mayorov, Alexander V ^a,b   Janda, Kim D ^a,b,c  

^a Department of Chemistry ^*  (United States)

^b Skaggs Institute for Chemical Biology   (United States)

^c SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

active vaccination; food intake; ghrelin; metabolism; monoclonal antibodies; passive vaccination

Indexed keywords

GHRELIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY JG2; MONOCLONAL ANTIBODY JG3; MONOCLONAL ANTIBODY JG4; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY AFFINITY; ARTICLE; BINDING AFFINITY; BREATHING RATE; CONTROLLED STUDY; DISPERSION; DRUG POTENTIATION; ENERGY EXPENDITURE; ENERGY METABOLISM; FOOD DEPRIVATION; FOOD INTAKE; HEAT; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; OBESITY; OXYGEN CONSUMPTION; PRIORITY JOURNAL; VACCINATION;

ANIMALS; ANTIBODIES, MONOCLONAL; EATING; ENERGY METABOLISM; EPITOPE MAPPING; FASTING; GHRELIN; HUMANS; MALE; MICE; MICE, INBRED C57BL; OBESITY; RATS;

EID: 84856857125     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200376c     Document Type: Article

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