Life span extension of Caenorhabditis elegans by novel pyridoperimidine derivative

Archives of Pharmacal Research

Volumn 35, Issue 1, 2012, Pages 69-76

  Sayed, Ahmed A R ^a,b   El Shaieb, Kamal M ^a   Mourad, Aboul Fetouh E ^a  

^a Minia University ^*  (Egypt)

^b KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Alkynes; C. elegans; Imidazoquinolines; Life spane; Pyridoperimidines

Indexed keywords

ANTIOXIDANT; IMIDAZO[4,5,1 IJ]QUINOLINE DERIVATIVE; METHYL 7 OXO 7H PYRIDO[1,2,3 CD]PERIMIDINE 9 CARBOXYLATE; PYRIDO[1,2,3 CD]PERIMIDINE; PYRIDOPERIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; BIOLOGICAL ACTIVITY; CAENORHABDITIS ELEGANS; CHEMICAL STRESS; GLYCATION; HEAT STRESS; LIFESPAN; NONHUMAN; WILD TYPE; WORM;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; LIFE EXPECTANCY; LONGEVITY; OXIDATIVE STRESS; QUINAZOLINES;

EID: 84856837151     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-012-0107-x     Document Type: Article

References (24)

1. A. A. Aly K. M. El-Shaieb 2004 Reaction of 1,8-diaminonaphthalene with some selected π-acceptors; prospective optically active non-linear cyanovinylated naphthalenes as well as synthesis of novel perimidin and pleiadene derivatives Tetrahedron 60 3797 3802 10.1016/j.tet.2004.03.017 1:CAS:528:DC%2BD2cXislyrsb0%3D (Pubitemid 38452852)
2. A. Bendich 1993 Physiological role of antioxidants in the immune system J. Dairy Sci. 76 2789 2794 8227682 10.3168/jds.S0022-0302(93)77617-1 1:CAS:528:DyaK3sXmt1Cqsro%3D
3. S. Brenner 1974 The genetics of Caenorhabditis elegans Genetics 77 71 94 4366476 1:STN:280:DyaE2c3ntFWlsw%3D%3D
4. R. Doonan J. J. McElwee F. Matthijssens G. A. Walker K. Houthoofd P. Back A. Matscheski J. R. Vanfleteren D. Gems 2008 Against the oxidative damage theory of aging: superoxide dismutases protect against oxidative stress but have little or no effect on life span in Caenorhabditis elegans Genes Dev. 22 3236 3241 19056880 10.1101/gad.504808 1:CAS:528:DC%2BD1cXhsFaiu7jJ
5. K. M. El-Shaieb R. M. Shaker A. A. Aly 2008 A Facile Route to the Synthesis of New 2,3-Disubstituted Benzocoumarins Synthetic Commun. 38 2054 2060 10.1080/00397910801997850 1:CAS:528:DC%2BD1cXntlagtrs%3D (Pubitemid 351873766)
6. T. Finkel N. J. Holbrook 2000 Oxidants, oxidative stress and the biology of ageing Nature 408 239 247 11089981 10.1038/35041687 1:CAS:528: DC%2BD3cXotFGltb0%3D
7. C. F. Glenn D. K. Chow L. David C. A. Cooke M. S. Gami W. B. Iser K. B. Hanselman I. G. Goldberg C. A. Wolkow 2004 Behavioral deficits during early stages of aging in Caenorhabditis elegans result from locomotory deficits possibly linked to muscle frailty J. Gerontol. A Biol. Sci. Med. Sci. 59 1251 1260 15699524 10.1093/gerona/59.12.1251 (Pubitemid 40209411)
8. L. Guarente C. Kenyon 2000 Genetic pathways that regulate ageing in model organisms Nature 408 255 262 11089983 10.1038/35041700 1:CAS:528: DC%2BD3cXotFGksrs%3D
9. D. Harman 1981 The aging process Proc. Natl. Acad. Sci. U. S. A. 78 7124 7128 6947277 10.1073/pnas.78.11.7124 1:CAS:528:DyaL38XktFGk
10. T. Heidler K. Hartwig D. Hannelore 2010 Caenorhabditis elegans lifespan extension caused by treatment with an orally active ROS-generator is dependent on DAF-16 and SIR-2.1 Biogerontology 11 183 195 19597959 10.1007/s10522-009- 9239-x 1:CAS:528:DC%2BC3cXis1ynsrw%3D
11. L. A. Herndon P. J. Schmeissner J. M. Dudaronek P. A. Brown K. M. Listner Y. Sakano M. C. Paupard D. H. Hall M. Driscoll 2002 Stochastic and genetic factors influence tissue-specific decline in ageing C. elegans Nature 419 808 814 12397350 10.1038/nature01135 1:CAS:528:DC%2BD38XovFyksb8%3D (Pubitemid 35238561)
12. B. Lakowski S. Hekimi 1998 The genetics of caloric restriction in Caenorhabditis elegans Proc. Natl. Acad. Sci. U. S. A. 95 13091 13096 9789046 10.1073/pnas.95.22.13091 1:CAS:528:DyaK1cXntFWkurc%3D (Pubitemid 28509529)
13. P. L. Larsen 1993 Aging and resistance to oxidative damage in Caenorhabditis elegans Proc. Natl. Acad. Sci. U. S. A. 90 8905 8909 8415630 10.1073/pnas.90.19.8905 1:CAS:528:DyaK2cXntlyitQ%3D%3D (Pubitemid 23306419)
14. L. J. Machlin A. Bendich 1987 Free radical tissue damage: protective role of antioxidant nutrients FASEB J. 1 441 445 3315807 1:CAS:528: DyaL1cXjs1GhtA%3D%3D
15. M. Morcos X. Du F. Pfisterer H. Hutter A. A. Sayed P. Thornalley N. Ahmed J. Baynes S. Thorpe G. Kukudov A. Schlotterer F. Bozorgmehr R. Abd El Baki D. Stern F. Moehrlen Y. Ibrahim D. Oikonomou A. Hamann C. Becker M. Zeier V. Schwenger N. Miftari P. Humpert H. P. Hammes M. Buechler A. Bierhaus M. Brownlee P. P. Nawroth 2008 Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans Aging Cell 7 260 269 18221415 10.1111/j.1474-9726.2008.00371.x 1:CAS:528:DC%2BD1cXksFeiu7Y%3D (Pubitemid 351359658)
16. A. A. R. Sayed 2011 Ferulsinaic acid attenuation of AGEs extends life span of Caenorhabditis elegans J. Pharm. Pharmacol. 63 423 428 21749391 10.1111/j.2042-7158.2010.01222.x 1:CAS:528:DC%2BC3MXksFOlt78%3D
17. Sayed, A. A., Thymoquinone and proanthocyanidin attenuation of diabetic nephropathy in rats. Eur. Rev. Med. Pharmacol. Sci., 2011 (in press).
18. A. Schlotterer G. Kukudov F. Bozorgmehr H. Hutter X. Du D. Oikonomou Y. Ibrahim F. Pfisterer N. Rabbani P. Thornalley A. Sayed T. Fleming P. Humpert V. Schwenger M. Zeier A. Hamann D. Stern M. Brownlee A. Bierhaus P. Nawroth M. Morcos 2009 C. elegans as model for the study of high glucose-mediated life span reduction Diabetes 58 2450 2456 19675139 10.2337/db09-0567 1:CAS:528: DC%2BD1MXhsVChtrfO
19. C. H. Scoggins 1981 The cellular basis of aging West J. Med. 135 521 525
20. J. M. Van Raamsdonk S. Hekimi 2009 Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans PLoS Genet. 5 e1000361 19197346 10.1371/journal.pgen.1000361
21. E. C. Wagner W. H. Millett 1943 Benzimidazole Org. Synth. Coll. 2 65
22. Z. Wagner I. Wittmann I. Mazak R. Schinzel A. Heidland R. Kientsch-Engel J. Nagy 2001 N(epsilon)-(carboxymethyl) lysine levels in patients with type 2 diabetes: role of renal function Am. J. Kidney Dis. 38 785 791 11576882 10.1053/ajkd.2001.27695 1:CAS:528:DC%2BD3MXnslKgs70%3D (Pubitemid 33666524)
23. M. A. Wilson B. Shukitt-Hale W. Kalt D. K. Ingram J. A. Joseph C. A. Wolkow 2006 Blueberry polyphenols increase lifespan and thermotolerance in Caenorhabditis elegans Aging Cell 5 59 68 16441844 10.1111/j.1474-9726.2006. 00192.x 1:CAS:528:DC%2BD28XislKnsrg%3D (Pubitemid 43348963)
24. L. Zhang J. Guoliang Z. Junjing Z. Baolu 2009 Significant longevity-extending effects of EGCG on Caenorhabditis elegans under stress Free Radic. Biol. Med. 46 414 421 19061950 10.1016/j.freeradbiomed.2008.10.041 1:CAS:528:DC%2BD1MXht1Wmug%3D%3D