Cytotoxic T cells to an epitope in the islet autoantigen IA-2 are not disease-specific

Clinical Immunology

Volumn 99, Issue 3, 2001, Pages 360-364

  Takahashi, Kazuma ^a   Honeyman, Margo C ^a   Harrison, Leonard C ^a  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Cytotoxic; Dendritic cell; HLA; T lymphocyte; Type 1 diabetes; Tyrosine phosphatase IA 2

Indexed keywords

AUTOANTIGEN; CD4 ANTIGEN; CHROMIUM 51; HLA A2 ANTIGEN; PROTEIN TYROSINE PHOSPHATASE;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNITY; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DIABETES MELLITUS; FEMALE; FLOW CYTOMETRY; HLA SYSTEM; HUMAN; HUMAN CELL; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PRIORITY JOURNAL; T LYMPHOCYTE;

EID: 0035013090     PISSN: 15216616     EISSN: None     Source Type: Journal    
DOI: 10.1006/clim.2001.5031     Document Type: Article

References (18)

1. + T lymphocytes: Clarification of their pathogenic roles in diabetes in the NOD mouse
2. Molecular mechanisms of pancreatic beta-cell destruction in autoimmune diabetes: Potential targets for preventive therapy
3. In situ characterization of autoimmune phenomena and expression of HLA molecules in the pancreas in diabetic insulitis
4. Macrophages, T cell receptor usage, and endothelial cell activation in the pancreas at the onset of insulin-dependent diabetes mellitus
5. Cellular immune response to diverse islet cell antigens in IDDM
6. Neural network-based prediction of candidate T-cell epitopes
7. Help for cytotoxic T-cell responses is mediated by CD40 signalling
8. + T-helper and a T-killer cell
9. Sinigaglia F: Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes
10. T-cell epitopes in the type 1 diabetes autoantigen tyrosine phosphatase IA-2: Potential for mimicry with rotavirus and other environmental agents
11. The Melbourne Pre-Diabetes Study: Screening for pre-clinical insulin-dependent diabetes in first-degree relatives of probands
12. Impaired assembly and transport of HLA-A and -B antigens in a mutant T×B cell hybrid
13. Scheme for ranking potential HLA-A2 binding peptides based on independent binding of individual peptide side-chains
14. HLA A2.1-restricted cytotoxic T cells recognising a range of Epstein-Barr virus isolates through a defined epitope in latent membrane protein LMP2
15. Two tyrosine nonapeptides recognized on HLA-A2 melanomas by autologous cytolytic T lymphocytes
16. Proliferating dendritic cell progenitors in human blood
17. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus interleukin 4 and downregulated by tumor necrosis factor alpha
18. Dendritic cells generated from human blood in granulocyte macrophage-colony stimulating factor and IL-7