Disruption of a glutathione reductase encoding gene in Acremonium chrysogenum leads to reduction of its growth, cephalosporin production and antioxidative ability which is recovered by exogenous methionine

Fungal Genetics and Biology

Volumn 49, Issue 2, 2012, Pages 114-122

  Long, Liang Kun ^a   Yang, Jing ^a   An, Yang ^a   Liu, Gang ^a  

^a INSTITUTE OF MICROBIOLOGY   (China)

Author keywords

Acremonium chrysogenum; Antioxidative activity; GlrA; Growth; Methionine

Indexed keywords

CEPHALOSPORIN; GENOMIC DNA; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE REDUCTASE; HYDROGEN PEROXIDE; METHIONINE;

AGAR DIFFUSION; ANTIBIOTIC BIOSYNTHESIS; ANTIBIOTIC SENSITIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CEPHALOSPORIUM ACREMONIUM; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; FERMENTATION; FUNGAL GENE; FUNGAL METABOLISM; FUNGAL SPORE GERMINATION; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS MUTANT; GENE DISRUPTION; GENE OVEREXPRESSION; GLRA GENE; GROWTH INHIBITION; MOLECULAR CLONING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; SEQUENCE HOMOLOGY; STRAIN DIFFERENCE; WILD TYPE;

ACREMONIUM; CEPHALOSPORINS; FERMENTATION; GENE EXPRESSION REGULATION, FUNGAL; GLUTATHIONE; GLUTATHIONE DISULFIDE; GLUTATHIONE REDUCTASE; HYPHAE; METHIONINE; MUTATION; SPORES, FUNGAL;

ACREMONIUM CHRYSOGENUM; EUKARYOTA; FUNGI;

EID: 84856801251     PISSN: 10871845     EISSN: 10960937     Source Type: Journal    
DOI: 10.1016/j.fgb.2011.12.004     Document Type: Article

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