-
1
-
-
79956319051
-
Progress and challenges in translating the biology of atherosclerosis
-
Libby P, Ridker PM, Hansson GK. Progress and challenges in translating the biology of atherosclerosis. Nature. 2011;473:317-325.
-
(2011)
Nature
, vol.473
, pp. 317-325
-
-
Libby, P.1
Ridker, P.M.2
Hansson, G.K.3
-
2
-
-
80355146868
-
Monocyte recruitment during infection and inflammation
-
Shi C, Pamer EG. Monocyte recruitment during infection and inflammation. Nat Rev Immunol. 2011;11:762-774.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 762-774
-
-
Shi, C.1
Pamer, E.G.2
-
3
-
-
33845970192
-
hi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata
-
DOI 10.1172/JCI29950
-
Swirski FK, Libby P, Aikawa E, Alcaide P, Luscinskas FW, Weissleder R, Pittet MJ. Ly-6Chi monocytes dominate hypercholesterolemiaassociated monocytosis and give rise to macrophages in atheromata. J Clin Invest. 2007;117:195-205. (Pubitemid 46048466)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 195-205
-
-
Swirski, F.K.1
Libby, P.2
Aikawa, E.3
Alcaide, P.4
Luscinskas, F.W.5
Weissleder, R.6
Pittet, M.J.7
-
4
-
-
34547492488
-
PPARγ activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
DOI 10.1016/j.cmet.2007.06.010, PII S1550413107001660
-
Bouhlel MA, Derudas B, Rigamonti E, Dievart R, Brozek J, Haulon S, Zawadzki C, Jude B, Torpier G, Marx N, Staels B, Chinetti-Gbaguidi G. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab. 2007;6: 137-143. (Pubitemid 47189091)
-
(2007)
Cell Metabolism
, vol.6
, Issue.2
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dievart, R.4
Brozek, J.5
Haulon, S.6
Zawadzki, C.7
Jude, B.8
Torpier, G.9
Marx, N.10
Staels, B.11
Chinetti-Gbaguidi, G.12
-
5
-
-
79954802715
-
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXR α pathways
-
Chinetti-Gbaguidi G, Baron M, Bouhlel MA, Vanhoutte J, Copin C, Sebti Y, Derudas B, Mayi T, Bories G, Tailleux A, Haulon S, Zawadzki C, Jude B, Staels B. Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXR α pathways. Circ Res. 2011; 108:985-995.
-
(2011)
Circ Res
, vol.108
, pp. 985-995
-
-
Chinetti-Gbaguidi, G.1
Baron, M.2
Bouhlel, M.A.3
Vanhoutte, J.4
Copin, C.5
Sebti, Y.6
Derudas, B.7
Mayi, T.8
Bories, G.9
Tailleux, A.10
Haulon, S.11
Zawadzki, C.12
Jude, B.13
Staels, B.14
-
6
-
-
34347354309
-
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
-
DOI 10.1038/nature05894, PII NATURE05894
-
Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red EA, Vats D, Brombacher F, Ferrante AW, Chawla A. Macrophage-specific PPARγ controls alternative activation and improves insulin resistance. Nature. 2007;447:1116-1120. (Pubitemid 47014427)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
7
-
-
0142116239
-
Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ
-
DOI 10.1126/science.1087344
-
Lee CH, Chawla A, Urbiztondo N, Liao D, Boisvert WA, Evans RM, Curtiss LK. Transcriptional repression of atherogenic inflammation: modulation by PPAR δ . Science. 2003;302:453-457. (Pubitemid 37296272)
-
(2003)
Science
, vol.302
, Issue.5644
, pp. 453-457
-
-
Lee, C.-H.1
Chawla, A.2
Urbiztondo, N.3
Liao, D.4
Boisvert, W.A.5
Evans, R.M.6
-
8
-
-
44349161098
-
Alternative M2 activation of kupffer cells by PPARδ ameliorates obesity-induced insulin resistance
-
DOI 10.1016/j.cmet.2008.04.003, PII S1550413108001137
-
Odegaard JI, Ricardo-Gonzalez RR, Red EA, Vats D, Morel CR, Goforth MH, Subramanian V, Mukundan L, Ferrante AW, Chawla A. Alternative M2 activation of Kupffer cells by PPAR δ ameliorates obesity-induced insulin resistance. Cell Metab. 2008;7:496-507. (Pubitemid 351729205)
-
(2008)
Cell Metabolism
, vol.7
, Issue.6
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red Eagle, A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
Subramanian, V.7
Mukundan, L.8
Ferrante, A.W.9
Chawla, A.10
-
9
-
-
33747196651
-
The NR4A subgroup: Immediate early response genes with pleiotropic physiological roles
-
Maxwell MA, Muscat GE. The NR4A subgroup: immediate early response genes with pleiotropic physiological roles. Nucl Recept Signal. 2006;4:e002.
-
(2006)
Nucl Recept Signal
, vol.4
-
-
Maxwell, M.A.1
Muscat, G.E.2
-
10
-
-
33645566549
-
NR4A1, 2, 3-an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis
-
Li QX, Ke N, Sundaram R, Wong-Staal F. NR4A1, 2, 3-an orphan nuclear hormone receptor family involved in cell apoptosis and carcinogenesis. Histol Histopathol. 2006;21:533-540.
-
(2006)
Histol Histopathol
, vol.21
, pp. 533-540
-
-
Li, Q.X.1
Ke, N.2
Sundaram, R.3
Wong-Staal, F.4
-
11
-
-
77957329141
-
Minireview: Nuclear hormone receptor 4A signaling: Implications for metabolic disease
-
Pearen MA, Muscat GE. Minireview: nuclear hormone receptor 4A signaling: implications for metabolic disease. Mol Endocrinol. 2010;24: 1891-1903.
-
(2010)
Mol Endocrinol
, vol.24
, pp. 1891-1903
-
-
Pearen, M.A.1
Muscat, G.E.2
-
13
-
-
80051959957
-
The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6Cmonocytes
-
Hanna RN, Carlin LM, Hubbeling HG, Nackiewicz D, Green AM, Punt JA, Geissmann F, Hedrick CC. The transcription factor NR4A1 (Nur77) controls bone marrow differentiation and the survival of Ly6Cmonocytes. Nat Immunol. 2011;12:778-785.
-
(2011)
Nat Immunol
, vol.12
, pp. 778-785
-
-
Hanna, R.N.1
Carlin, L.M.2
Hubbeling, H.G.3
Nackiewicz, D.4
Green, A.M.5
Punt, J.A.6
Geissmann, F.7
Hedrick, C.C.8
-
14
-
-
79953769170
-
The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells
-
Sekiya T, Kashiwagi I, Inoue N, Morita R, Hori S, Waldmann H, Rudensky AY, Ichinose H, Metzger D, Chambon P, Yoshimura A. The nuclear orphan receptor Nr4a2 induces Foxp3 and regulates differentiation of CD4+ T cells. Nat Commun. 2011;2:269.
-
(2011)
Nat Commun
, vol.2
, pp. 269
-
-
Sekiya, T.1
Kashiwagi, I.2
Inoue, N.3
Morita, R.4
Hori, S.5
Waldmann, H.6
Rudensky, A.Y.7
Ichinose, H.8
Metzger, D.9
Chambon, P.10
Yoshimura, A.11
-
15
-
-
64249118416
-
The orphan nuclear receptor Nur77 suppresses endothelial cell activation through induction of Iκ Balpha expression
-
You B, Jiang YY, Chen S, Yan G, Sun J. The orphan nuclear receptor Nur77 suppresses endothelial cell activation through induction of Iκ Balpha expression. Circ Res. 2009;104:742-749.
-
(2009)
Circ Res
, vol.104
, pp. 742-749
-
-
You, B.1
Jiang, Y.Y.2
Chen, S.3
Yan, G.4
Sun, J.5
-
16
-
-
77952240075
-
Nuclear receptor Nurr1 is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation
-
Bonta PI, Pols TW, van Tiel CM, Vos M, Arkenbout EK, Rohlena J, Koch KT, de Maat MP, Tanck MW, de Winter RJ, Pannekoek H, Biessen EA, Bot I, de Vries CJ. Nuclear receptor Nurr1 is expressed in and is associated with human restenosis and inhibits vascular lesion formation in mice involving inhibition of smooth muscle cell proliferation and inflammation. Circulation. 2010;121:2023-2032.
-
(2010)
Circulation
, vol.121
, pp. 2023-2032
-
-
Bonta, P.I.1
Pols, T.W.2
Van Tiel, C.M.3
Vos, M.4
Arkenbout, E.K.5
Rohlena, J.6
Koch, K.T.7
De Maat, M.P.8
Tanck, M.W.9
De Winter, R.J.10
Pannekoek, H.11
Biessen, E.A.12
Bot, I.13
De Vries, C.J.14
-
17
-
-
33846620640
-
Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation
-
DOI 10.1161/CIRCULATIONAHA.106.626838, PII 0000301720070130000012
-
Pires NM, Pols TW, de Vries MR, van Tiel CM, Bonta PI, Vos M, Arkenbout EK, Pannekoek H, Jukema JW, Quax PH, de Vries CJ. Activation of nuclear receptor Nur77 by 6-mercaptopurine protects against neointima formation. Circulation. 2007;115:493-500. (Pubitemid 46184201)
-
(2007)
Circulation
, vol.115
, Issue.4
, pp. 493-500
-
-
Pires, N.M.M.1
Pols, T.W.H.2
De Vries, M.R.3
Van Tiel, C.M.4
Bonta, P.I.5
Vos, M.6
Arkenbout, E.K.7
Pannekoek, H.8
Jukema, J.W.9
Quax, P.H.A.10
De Vries, C.J.M.11
-
18
-
-
33744738277
-
TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells
-
DOI 10.2353/ajpath.2006.050932
-
de Waard V, Arkenbout EK, Vos M, Mocking AI, Niessen HW, Stooker W, de Mol BA, Quax PH, Bakker EN, VanBavel E, Pannekoek H, de Vries CJ. TR3 nuclear orphan receptor prevents cyclic stretch-induced proliferation of venous smooth muscle cells. Am J Pathol. 2006;168: 2027-2035. (Pubitemid 43825321)
-
(2006)
American Journal of Pathology
, vol.168
, Issue.6
, pp. 2027-2035
-
-
De Waard, V.1
Arkenbout, E.K.2
Vos, M.3
Mocking, A.I.M.4
Niessen, H.W.M.5
Stooker, W.6
De Mol, B.A.J.M.7
Quax, P.H.A.8
Bakker, E.N.T.P.9
VanBavel, E.10
Pannekoek, H.11
De Vries, C.J.M.12
-
19
-
-
77954783328
-
Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels
-
Bonta PI, Matlung HL, Vos M, Peters SL, Pannekoek H, Bakker EN, de Vries CJ. Nuclear receptor Nur77 inhibits vascular outward remodelling and reduces macrophage accumulation and matrix metalloproteinase levels. Cardiovasc Res. 2010;87:561-568.
-
(2010)
Cardiovasc Res
, vol.87
, pp. 561-568
-
-
Bonta, P.I.1
Matlung, H.L.2
Vos, M.3
Peters, S.L.4
Pannekoek, H.5
Bakker, E.N.6
De Vries, C.J.7
-
20
-
-
61349097172
-
Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury
-
Nomiyama T, Zhao Y, Gizard F, Findeisen HM, Heywood EB, Jones KL, Conneely OM, Bruemmer D. Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury. Circulation. 2009;119:577-586.
-
(2009)
Circulation
, vol.119
, pp. 577-586
-
-
Nomiyama, T.1
Zhao, Y.2
Gizard, F.3
Findeisen, H.M.4
Heywood, E.B.5
Jones, K.L.6
Conneely, O.M.7
Bruemmer, D.8
-
21
-
-
77956229621
-
Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis
-
Zhao Y, Howatt DA, Gizard F, Nomiyama T, Findeisen HM, Heywood EB, Jones KL, Conneely OM, Daugherty A, Bruemmer D. Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis. Circ Res. 2010;107:501-511.
-
(2010)
Circ Res
, vol.107
, pp. 501-511
-
-
Zhao, Y.1
Howatt, D.A.2
Gizard, F.3
Nomiyama, T.4
Findeisen, H.M.5
Heywood, E.B.6
Jones, K.L.7
Conneely, O.M.8
Daugherty, A.9
Bruemmer, D.10
-
22
-
-
84856707159
-
NR4A1 (Nur77) Deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis
-
Hanna RN, Shaked I, Hubbeling HG, Punt JA, Wu R, Herrley E, Zaugg C, Pei H, Geissmann F, Ley K, Hedrick CC. NR4A1 (Nur77) Deletion polarizes macrophages toward an inflammatory phenotype and increases atherosclerosis. Circ Res. 2012;110:416-427.
-
(2012)
Circ Res
, vol.110
, pp. 416-427
-
-
Hanna, R.N.1
Shaked, I.2
Hubbeling, H.G.3
Punt, J.A.4
Wu, R.5
Herrley, E.6
Zaugg, C.7
Pei, H.8
Geissmann, F.9
Ley, K.10
Hedrick, C.C.11
-
23
-
-
84856752344
-
Bone marrow-specific deficiency of nuclear receptor Nur77 enhances atherosclerosis
-
Hamers AA, Vos M, Rassam F, van Gorp PJ, de Winther MP, Gijbels MJ, de Waard V, de Vries CJ. Bone marrow-specific deficiency of nuclear receptor Nur77 enhances atherosclerosis. Circ Res. 2012;110:428-438.
-
(2012)
Circ Res
, vol.110
, pp. 428-438
-
-
Hamers, A.A.1
Vos, M.2
Rassam, F.3
Van Gorp, P.J.4
De Winther, M.P.5
Gijbels, M.J.6
De Waard, V.7
De Vries, C.J.8
-
24
-
-
33645411885
-
Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77
-
Pei L, Castrillo A, Tontonoz P. Regulation of macrophage inflammatory gene expression by the orphan nuclear receptor Nur77. Mol Endocrinol. 2006;20:786-794.
-
(2006)
Mol Endocrinol
, vol.20
, pp. 786-794
-
-
Pei, L.1
Castrillo, A.2
Tontonoz, P.3
-
25
-
-
33749061994
-
Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses
-
DOI 10.1161/01.ATV.0000238346.84458.5d, PII 0004360520061000000020
-
Bonta PI, van Tiel CM, Vos M, Pols TW, van Thienen JV, Ferreira V, Arkenbout EK, Seppen J, Spek CA, van der PT, Pannekoek H, de Vries CJ. Nuclear receptors Nur77, Nurr1, and Nor-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses. Arterioscler Thromb Vasc Biol. 2006;26:2288-2294. (Pubitemid 44465724)
-
(2006)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.26
, Issue.10
, pp. 2288-2294
-
-
Bonta, P.I.1
Van Tiel, C.M.2
Vos, M.3
Pols, T.W.H.4
Van Thienen, J.V.5
Ferreira, V.6
Arkenbout, E.K.7
Seppen, J.8
Spek, C.A.9
Van Der Poll, T.10
Pannekoek, H.11
De Vries, C.J.M.12
-
26
-
-
0029857001
-
Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1
-
DOI 10.1210/me.10.12.1656
-
Zetterstrom RH, Solomin L, Mitsiadis T, Olson L, Perlmann T. Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. Mol Endocrinol. 1996;10:1656-1666. (Pubitemid 26408753)
-
(1996)
Molecular Endocrinology
, vol.10
, Issue.12
, pp. 1656-1666
-
-
Zetterstrom, R.H.1
Solomin, L.2
Mitsiadis, T.3
Olson, L.4
Perlmann, T.5
|