5, 7-Dimethoxyflavone sensitizes TRAIL-induced apoptosis through DR5 upregulation in hepatocellular carcinoma cells

Cancer Chemotherapy and Pharmacology

Volumn 69, Issue 1, 2012, Pages 195-206

  Yang, Jian Feng ^a   Cao, Jian Guo ^a   Tian, Li ^a   Liu, Fei ^a  

^a HUNAN NORMAL UNIVERSITY   (China)

Author keywords

5, 7 Dimethoxyflavone; DR5; Hepatocellular carcinoma; Reactive oxygen species; TRAIL

Indexed keywords

2,3 DIHYDRO 5 METHYL 3 (MORPHOLINOMETHYL) 6 (1 NAPHTHOYL)PYRROLO[1,2,3 DE][1,4]BENZOXAZINE; 5,7 DIMETHOXYFLAVONE; ACTIVATING TRANSCRIPTION FACTOR 4; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLLEUCYLGLUTAMYLHISTIDYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FLAVONOID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 78; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; REACTIVE OXYGEN METABOLITE; SMALL INTERFERING RNA; TETRAZOLIUM; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG;

AGAR GEL ELECTROPHORESIS; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL CYCLE G1 PHASE; CELL DEATH; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; DOSE RESPONSE; DRUG CYTOTOXICITY; DRUG SENSITIZATION; EMBRYO; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL CARCINOMA; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING;

APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL LINE; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; FLAVONOIDS; HUMANS; LEUKOCYTES, MONONUCLEAR; LIVER; LIVER NEOPLASMS; REACTIVE OXYGEN SPECIES; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; RNA, SMALL INTERFERING; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TRANSCRIPTION FACTOR CHOP; UP-REGULATION;

EID: 84856753924     PISSN: 03445704     EISSN: 14320843     Source Type: Journal    
DOI: 10.1007/s00280-011-1686-9     Document Type: Article

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