Myeloperoxidase-derived oxidants inhibit sarco/endoplasmic reticulum Ca 2 +-ATPase activity and perturb Ca 2 + homeostasis in human coronary artery endothelial cells

Free Radical Biology and Medicine

Volumn 52, Issue 5, 2012, Pages 951-961

  Cook, Naomi L ^a   Viola, Helena M ^b   Sharov, Victor S ^c   Hool, Livia C ^b   Schöneich, Christian ^c   Davies, Michael J ^a,d  

^a HEART RESEARCH INSTITUTE   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF KANSAS   (United States)

^d University of Sydney   (Australia)

Author keywords

Calcium; Free radicals; Hypochlorous acid; Hypothiocyanous acid; Myeloperoxidase; Oxidation; Sarco endoplasmic reticulum Ca 2 + ATPase; SERCA; Thiols

Indexed keywords

HYPOCHLOROUS ACID; HYPOTHIOCYANOUS ACID; MYELOPEROXIDASE; OXIDIZING AGENT; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; THAPSIGARGIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORONARY ARTERY; ENDOPLASMIC RETICULUM; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; RAT; SARCOPLASMIC RETICULUM;

CALCIUM; CALCIUM SIGNALING; CELLS, CULTURED; CHLORAMINES; CORONARY VESSELS; ENDOPLASMIC RETICULUM; ENDOTHELIAL CELLS; HUMANS; HYPOCHLOROUS ACID; OXIDANTS; OXIDATION-REDUCTION; PEROXIDASE; SARCOPLASMIC RETICULUM; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SULFHYDRYL COMPOUNDS; THIOCYANATES;

EID: 84856742841     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.12.001     Document Type: Article

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