Hypothiocyanous acid reactivity with low-molecular-mass and protein thiols: Absolute rate constants and assessment of biological relevance

Biochemical Journal

Volumn 422, Issue 1, 2009, Pages 111-117

  Skaff, Ojia ^a   Pattison, David I ^a   Davies, Michael J ^a,b  

^a HEART RESEARCH INSTITUTE   (Australia)

^b University of Sydney   (Australia)

Author keywords

Hypothiocyanous acid (HOSCN); Kinetics; Lactoperoxidase; Myeloperoxidase; Thiols

Indexed keywords

ACETYL-CYSTEINE; CREATINE KINASE; CYSTEINE RESIDUES; EOSINOPHIL PEROXIDASE; HYPOBROMOUS ACID; HYPOCHLOROUS ACIDS; HYPOTHIOCYANOUS ACID (HOSCN); INVERSE RELATIONSHIP; KINETIC DATA; LACTOGLOBULIN; LACTOPEROXIDASE; MYELOPEROXIDASE; NITROBENZOIC ACIDS; OXIDATIVE DAMAGE; OXIDIZING AGENTS; PHYSIOLOGICAL CONCENTRATIONS; PROTEIN THIOLS; RATE OF REACTION; SECOND-ORDER RATE CONSTANTS; THIOL GROUPS; THIOL OXIDATION; THIOLS;

ACIDS; BIOLOGICAL SYSTEMS; CARBOXYLIC ACIDS; CHLORINE COMPOUNDS; OXIDANTS; OXIDATION; PROTEINS;

RATE CONSTANTS;

5 THIO NITROBENZOIC ACID; ACETYLCYSTEINE; BETA CRYSTALLIN; BETA LACTOGLOBULIN; BOVINE SERUM ALBUMIN; CREATINE KINASE; CYSTEINE; GLUTATHIONE PEROXIDASE; HALIDE; HYDROGEN PEROXIDE; HYPOTHIOCYANOUS ACID; MECYSTEINE; MERCAPTAMINE; NITROBENZOIC ACID DERIVATIVE; OXIDIZING AGENT; PENICILLAMINE; PEROXIDASE; THIOCYANATE; THIOL; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL INTERACTION; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; ENZYME SUBSTRATE; OXIDATION; PRIORITY JOURNAL;

ANIMALS; CATTLE; GLUTATHIONE; HYDROGEN-ION CONCENTRATION; KINETICS; MOLECULAR WEIGHT; NITROBENZOATES; PROTEINS; SULFHYDRYL COMPOUNDS; THIOCYANATES;

EID: 68749097272     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20090276     Document Type: Article

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