Impact of genetic variations of the CYP1A1, GSTT1, and GSTM1 genes on the risk of coronary artery disease

DNA and Cell Biology

Volumn 31, Issue 2, 2012, Pages 211-218

  Taspinar, Mehmet ^a   Aydos, Sena ^a   Sakiragaoglu, Onur ^a   Duzen, Irfan Veysel ^a   Yalcinkaya, Adnan ^b   Oztuna, Derya ^a   Bardakci, Hasmet ^b   Tutar, Eralp ^a   Sunguroglu, Asuman ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b TURKIYE YUKSEK IHTISAS HOSPITAL   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 1A1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE T1;

ADULT; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; FEMALE; GENE INTERACTION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

AGED; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; CYTOCHROME P-450 CYP1A1; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPE; GLUTATHIONE TRANSFERASE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK;

EID: 84856739949     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1252     Document Type: Article

References (62)

1. Abu-Amero, K.K., Al-Boudari, O.M., Mohamed, G.H., and Dzimiri, N. (2006). T null and M null genotypes of the glutathione S-transferase gene are risk factor for CAD independent of smoking. BMC Med Genet 7, 38.
2. Ada, A.O., Süzen, S.H., and Iscan, M. (2004). Polymorphisms of cytochrome P450 1A1, glutathione S-transferases M1 and T1 in a Turkish population. Toxicol Lett 151, 311-315. (Pubitemid 38739054)
3. Andreassi, M.G., Botto, N., Colombo, M.G., Biagini, A., and Clerico, A. (2000). Genetic instability and atherosclerosis: can somatic mutations account for the development of cardiovascular diseases? Environ Mol Mutagen 35, 265-269. (Pubitemid 30434603)
4. Aydemir, B., Onaran, I., Kiziler, A.R., Alici, B., and Akyolcu, M.C. (2007). Increased oxidative damage of sperm and seminal plasma in men with idiopathic infertility is higher in patients with glutathione S-transferase Mu-1 null genotype. Asian J Androl 9, 108-115. (Pubitemid 46050225)
5. Aydin-Sayitoglu, M., Hatirnaz, O., Erensoy, N., and Ozbek, U. (2006). Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias. Am J Hematol 81, 162-170.
6. Aydos, S.E., Taspinar, M., Sunguroglu, A., Aydos, K. (2009). Association of CYP1A1 and glutathione S-transferase polymorphisms with male factor infertility. Fertil Steril 92, 541-547.
7. Aynacioglu, A.S., Cascorbi, I., Mrozikiewicz, P.M., and Roots, I. (1998). High frequency of CYP1A1 mutations in a Turkish population. Arch Toxicol 72, 215-218. (Pubitemid 28164016)
8. Barouki, R., and Morel, Y. (2001). Repression of cytochrome P450 1A1 gene expression by oxidative stress: mechanisms and biological implications. Biochem Pharmacol 61, 511-516. (Pubitemid 32178484)
9. Bartsch, H., Nair, U., Risch, A., Rojas, M., Wikman, H., and Alexandrov, K. (2000). Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers. Cancer Epidemiol Biomarkers Prev 9, 3-28. (Pubitemid 30062906)
10. Benditt, E.P., and Benditt, J.M. (1973). Evidence for a monoclonal origin of human atherosclerotic plaques. Proc Natl Acad Sci USA 70, 1753-1756.
11. Binková, B., Smerhovský, Z., Strejc, P., Boubelík, O., Stávková, Z., Chvátalová, I., and Srám, R.J. (2002). DNA-adducts and atherosclerosis: a study of accidental and sudden death males in the Czech Republic. Mutat Res 501, 115-128. (Pubitemid 34270656)
12. Bridges, B.A., Bowyer, D.E., Hansen, E.S., Penn, A., and Wakabayashi, K. (1990). The possible involvement of somatic mutations in the development of atherosclerotic plaques. Mutat Res 239, 143-148.
13. Canalle, R., Burim, R.V., Tone, L.G., and Takahashi, C.S. (2004). Genetic polymorphisms and susceptibility to childhood acute lymphoblastic leukemia. Environ Mol Mutagen 43, 100-109. (Pubitemid 38332725)
14. Cascorbi, I., Brockmöller, J., and Roots, I. (1996). A C4887A polymorphism in exon 7 of human CYP1A1: population frequency, mutation linkages, and impact on lung cancer susceptibility. Cancer Res 56, 4965-4969. (Pubitemid 26374436)
15. D'Alò, F., Voso, M.T., Guidi, F., Massini, G., Scardocci, A., Sica, S., Pagano, L., Hohaus, S., and Leone, G. (2004). Polymorphisms of CYP1A1 and glutathione S-transferase and susceptibility to adult acute myeloid leukemia. Haematologica 89, 664-670. (Pubitemid 38828472)
16. De Flora, S., Izzotti, A., Walsh, D., Degan, P., Petrilli, G.L., and Lewtas, J. (1997). Molecular epidemiology of atherosclerosis. FASEB J 11, 1021-1031. (Pubitemid 27425904)
17. De Flora, S., and Izotti, A. (2007). Mutagenesis and cardiovascular diseases Molecular mechanisms, risk factors, and protective factors. Mutat Res 621, 5-17. (Pubitemid 47042066)
18. García-Suástegui, W.A., Huerta-Chagoya, A., Carrasco-Colín, K.L., Pratt, M.M., John, K., Petrosyan, P., Rubio, J., Poirier, M.C., and Gonsebatt, M.E. (2011). Seasonal variations in the levels of PAH-DNA adducts in young adults living in Mexico City. Mutagenesis 26, 385-391.
19. Gaspar, P.A., Hutz, M.H., Salzano, F.M., Hill, K., Hurtado, A.M., Petzl-Erler, M.L., Tsuneto, L.T., and Weimer, T.A. (2002). Polymorphisms of CYP1a1, CYP2e1, GSTM1, GSTT1, and TP53 genes in Amerindians. Am J Phys Anthropol 119, 249-256. (Pubitemid 35191429)
20. Girisha, K.M., Gilmour, A., Mastana, S., Singh, V.P., Sinha, N., Tewari, S., Ramesh, V., Sankar, V.H., and Agrawal, S. (2004). T1 And M1 polymorphism in glutathione S-transferase gene and coronary artery disease in North Indian population. Indian J Med Sci 58, 520-526.
21. Gravina, P., Spoletini, I., Masini, S., Valentini, A., Vanni, D., Paladini, E., Bossù, P., Caltagirone, C., Federici, G., Spalletta, G., and Bernardini, S. (2011). Genetic polymorphisms of glutathione S-transferases GSTM1, GSTT1, GSTP1 and GSTA1 as risk factors for schizophrenia. Psychiatry Res 187, 454-456.
22. Guengerich, F.P. (2000). Metabolism of chemical carcinogens. Carcinogenesis 21, 345-351. (Pubitemid 30137919)
23. Güven, M., Görgün, E., Unal, M., Yenerel, M., Batar, B., Küçü-men, B., Dinç, U.A., Güven, G.S., Ulus, T., and Yüksel, A. (2011). Glutathione S-transferase M1, GSTT1 and GSTP1 genetic polymorphisms and the risk of age-related macular degeneration. Ophthalmic Res 46, 31-37.
24. Hayashi, S.I., Watanabe, J., Nakachi, K., and Kawajiri, K. (1991). PCR detection of an A/G polymorphism within exon 7 of the CYP1A1 gene. Nucleic Acids Res 19, 4797.
25. Hintze, J. (2001). NCSS and PASS. Kaysville (UT): Number Cruncher Statistical Systems. Available at www.ncss.com
26. Izzotti, A., Cartiglia, C., Lewtas, J., and De Flora, S. (2001). Increased, DNA alterations in atherosclerotic lesions of individuals lacking the GSTM1 genotype. FASEB J 15, 752-757. (Pubitemid 32245993)
27. Jarvis, M.D., Palmer, B.R., Pilbrow, A.P., Ellis, K.L., Frampton, C.M., Skelton, L., Doughty, R.N., Whalley, G.A., Ellis, C.J., Yandle, T.G., Richards, A.M., and Cameron, V.A. (2010). CYP1A1 MSPI (T6235C) gene polymorphism is associated with mortality in acute coronary syndrome patients. Clin Exp Pharmacol Physiol 37, 193-198.
28. Jones, T.D., Morris, M.D., and Basavaraju, S.R. (1998). Atherosclerotic risks from chemicals: part II. A RASH analysis of in vitro and in vivo bioassay data to evaluate 45 potentially hazardous compounds. Arch Environ Contam Toxicol 35, 165-177. (Pubitemid 28275505)
29. Ketterer, B., Harris, J.M., Talaska, G., Meyer, D.J., Pemble, S.E., Taylor, J.B., Lang, N.P., and Kadlubar, F.F. (1992). The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer. Environ Health Perspect 98, 87-94. (Pubitemid 23061787)
30. Kim, S.J., Kim, M.G., Kim, K.S., Song, J.S., Yim, S.V., and Chung, J.H. (2008). Impact of glutathione S-transferase M1 and T1 gene polymorphisms on the smoking-related coronary artery disease. J Korean Med Sci 23, 365-372.
31. Krajinovic, M., Labuda, D., Richer, C., Karimi, S., and Sinnet, D. (1999). Susceptibility to childhood acute lymphoblastic leukemia: influence of CYP1A1, CYP2D6, GSTM1, and GSTT1 genetic polymorphisms. Blood 93, 1496-1501. (Pubitemid 29102475)
32. Kvitko, K., Nunes, J.C., Weimer, T.A., Salzano, F.M., and Hutz, M.H. (2000). Cytochrome P4501A1 polymorphisms in South American Indians. Hum Biol 72, 1039-1043. (Pubitemid 32152226)
33. Lu, N., Wu, B., Xia, Y., Wang, W., Gu, A., Liang, J., Lu, C., Song, L., Wang, S., Peng, Y., Zhang, Z., and Wang, X. (2008). Polymorphisms in CYP1A1 gene are associated with male infertility in a Chinese population. Int J Androl 31, 527-533.
34. Maciel, S.S., Pereira Ada, C., Silva, G.J., Rodrigues, M.V., Mill, J.G., and Krieger, J.E. (2009). Association between glutathione S-transferase polymorphisms and triglycerides and HDLcholesterol. Atherosclerosis 206, 204-208.
35. Manfredi, S., Calvi, D., del Fiandra, M., Botto, N., Biagini, A., and Andreassi, M.G. (2009). Glutathione S-transferase T1-and M1-null genotypes and coronary artery disease risk in patients with Type 2 diabetes mellitus. Pharmacogenomics 10, 29-34.
36. Manfredi, S., Federici, C., Picano, E., Botto, N., Rizza, A., and Andreassi, M.G. (2007). GSTM1, GSTT1 and CYP1A1 detoxification gene polymorphisms and susceptibility to smokingrelated coronary artery disease: a case-only study. Mutat Res 621, 106-112. (Pubitemid 47042075)
37. Martin, N.J., Collier, A.C., Bowen, L.D., Pritsos, K.L., Goodrich, G.G., Arger, K., Cutter, G., and Pritsos, C.A. (2009). Polymorphisms in the NQO1, GSTT and GSTM genes are associated with coronary heart disease and biomarkers of oxidative stress. Mutat Res 674, 93-100.
38. Masetti, S., Botto, N., Manfredi, S., Colombo, M.G., Rizza, A., Vassalle, C., Clerico, A., Biagini, A., and Andreassi, M.G. (2003). Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk. J Mol Med 81, 488-494. (Pubitemid 37070201)
39. O'Toole, T.E., Conklin, D.J., and Bhatnagar, A. (2008). Environmental risk factors for heart disease. Rev Environ Health 23, 167-202.
40. Penn, A. (1990). International Commission for Protection Against Environmental Mutagens and Carcinogens. ICPEMC Working Paper 7/1/1. Mutational events in the etiology of arteriosclerotic plaques. Mutat Res 239, 149-162.
41. Perera, F.P. (1996). Molecular epidemiology: insights into cancer susceptibility, risk assessment, and prevention. J Natl Cancer Inst 88, 496-509. (Pubitemid 26118720)
42. Ross, R. (1993). Rous-Whipple Award Lecture. Atherosclerosis: a defense mechanism gone awry. Am J Pathol 143, 987-1002. (Pubitemid 24070539)
43. Ross, R., and Glomset, J.A. (1973). Atherosclerosis and the arterial smooth muscle cell: proliferation of smooth muscle is a key event in the genesis of the lesions of atherosclerosis. Science 180, 1332-1339.
44. Rushmore, T.H., and Pickett, C.B. (1993). Glutathione S-transferases, structure, regulation, and therapeutic implications. J Biol Chem 268, 11475-11478. (Pubitemid 23168082)
45. Sabitha, K., Reddy, M.V., and Jamil, K. (2010). Smoking related risk involved in individuals carrying genetic variants of CYP1A1 gene in head and neck cancer. Cancer Epidemiol 34, 587-592.
46. Salama, S.A., Au, W.W., Hunter, G.C., Sheahan, R.G., Badary, O.A., Abdel-Naim, A.B., and Hamada, F.M. (2002). Polymorphic metabolizing genes and susceptibility to atherosclerosis among cigarette smokers. Environ Mol Mutagen 40, 153-160.
47. Sambrook, J., Fritsch, E.F., and Maniatis, T. (1982). Molecular Cloning a Laboratory Manual, 2nd edition. (Cold Spring Harbor Lobisiçanory Press, Cold Spring Harbor, NY).
48. Sankaranarayanan, K., Chakraborty, R., and Boerwinkle, E.A. (1999). Ionizing radiation and genetic risks. VI. Chronic multifactorial diseases: a review of epidemiological and genetic aspects of coronary heart disease, essential hypertension and diabetes mellitus. Mutat Res 436, 21-57. (Pubitemid 29045760)
49. Schuppe, H.C., Wieneke, P., Donat, S., Fritsche, E., Köhn, F.M., and Abel, J. (2000). Xenobiotic metabolism, genetic polymorphisms and male infertility. Andrologia 32, 255-262.
50. Shimada, T., Hayes, C.L., Yamazaki, H., Amin, S., Hecht, S.S., Guengerich, F.P., and Sutter, T.R. (1996). Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1. Cancer Res 56, 2979-2984. (Pubitemid 26199741)
51. Song, N., Tan, W., Xing, D., and Lin, D. (2001). CYP 1A1 polymorphism and risk of lung cancer in relation to tobacco smoking: a case-control study in China. Carcinogenesis 22, 11-16. (Pubitemid 32098138)
52. Takanashi, M., Morimoto, A., Yagi, T., Kuriyama, K., Kano, G., Imamura, T., Hibi, S., Todo, S., and Imashuku, S. (2003). Impact of glutathione S-transferase gene deletion on early relapse in childhood B-precursor acute lymphoblastic leukemia. Haematologica 88, 1238-1244. (Pubitemid 37456378)
53. Tamer, L., Ercan, B., Camsari, A., Yildirim, H., Ciçek, D., Sucu, N., Atesx, N.A., and Atik, U. (2004). Glutathione S-transferase gene polymorphism as a susceptibility factor in smoking-related coronary artery disease. Basic Res Cardiol 99, 223-229. (Pubitemid 38594230)
54. Tang, J.J., Wang, M.W., Jia, E.Z., Yan, J.J., Wang, Q.M., Zhu, J., Yang, Z.J., Lu, X., and Wang, L.S. (2010). The common variant in the GSTM1 and GSTT1 genes is related to markers of oxidative stress and inflammation in patients with coronary artery disease: a case-only study. Mol Biol Rep 37, 405-410.
55. Taspinar, M., Aydos, S.E., Comez, O., Elhan, A.H., Karabulut, H.G., Sunguroglu, A. (2008). CYP1A1, GST gene polymorphisms and risk of chronic myeloid leukemia. Swiss Med Wkly 138, 12-17. (Pubitemid 351192768)
56. Tsatsakis, A.M., Zafiropoulos, A., Tzatzarakis, M.N., Tzanakakis, G.N., and Kafatos, A. (2009). Relation of PON1 and CYP1A1 genetic polymorphisms to clinical findings in a crosssectional study of a Greek rural population professionally exposed to pesticides. Toxicol Lett 186, 66-72.
57. Unal, M., Güven, M., Devranoǧlu, K., Ozaydin, A., Batar, B., Tamçelik, N., Görgün, E.E., Uçar, D., and Sarici, A. (2007). Glutathione S transferase M1 and T1 genetic polymorphisms are related to the risk of primary open-angle glaucoma: a study in a Turkish population. Br J Ophthalmol 91, 527-530. (Pubitemid 46623690)
58. Van Schooten, F.J., Hirvonen, A., Maas, L.M., De Mol, B.A., Kleinjans, J.C., Bell, D.A., and Durrer, J.D. (1998). Putative susceptibility markers of coronary artery disease: association between VDR genotype, smoking, and aromatic DNA adduct levels in human right atrial tissue. FASEB J 12, 1409-1417. (Pubitemid 28475583)
59. Wang, L.S., Tang, J.J., Tang, N.P., Wang, M.W., Yan, J.J, Wang, Q.M.,Yang, Z.J., andWang, B. (2008). Association ofGSTM1and GSTT1 gene polymorphisms with coronary artery disease in relation to tobacco smoking. Clin ChemLabMed 46, 1720-1725.
60. Wilson, M.H., Grant, P.J., Hardie, L.J., and Wild, C.P. (2000). Glutathione S-transferase M1 null genotype is associated with a decreased risk of myocardial infarction. FASEB J 14, 791-796. (Pubitemid 30198577)
61. Yeh, C.C., Sung, F.C., Kuo, L.T., Hsu, W.P., and Chu, H.Y. (2009). Polymorphisms of cytochrome P450 1A1, cigarette smoking and risk of coronary artery disease. Mutat Res 667, 77-81.
62. Yildiz, M., Karkucak, M., Yakut, T., Gorukmez, O., and Ozmen, A. (2010). Lack of association of genetic polymorphisms of angiotensin-converting enzyme gene I/D and glutathione-Stransferase enzyme T1 and M1 with retinopathy of prematures. Genet Mol Res 9, 2131-2139.