A tannic acid-based medical food, cesinex ®, exhibits broad-spectrum antidiarrheal properties: A mechanistic and clinical study

Digestive Diseases and Sciences

Volumn 57, Issue 1, 2012, Pages 99-108

  Ren, Aixia ^a   Zhang, Weiqiang ^a   Thomas, Hugh Greg ^b   Barish, Amy ^b   Berry, Stephen ^b   Kiel, Jeffrey S ^b   Naren, Anjaparavanda P ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Avery Dennison RFID Division   (United States)

Author keywords

Cesinex ; Chloride channels; Diarrhea; Intestinal barrier; Intestinal fluid secretion; Tannic acid

Indexed keywords

ANTIDIARRHEAL AGENT; CESINEX; CHLORIDE; CHOLERA TOXIN; TANNIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIDIARRHEAL ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CELL VIABILITY; CHEMICAL COMPOSITION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DEFECATION; DIARRHEA; DRUG EFFICACY; DRUG TOLERABILITY; FECES ANALYSIS; FOOD; GASTROINTESTINAL SYMPTOM; HUMAN; HUMAN CELL; HUMAN ROTAVIRUS; INTESTINE EPITHELIUM; INTESTINE EPITHELIUM CELL; INTESTINE FLUID; MEDICAL FOOD; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PRESCHOOL CHILD; PRIORITY JOURNAL; PRURITUS; RASH; RETROSPECTIVE STUDY; SCHOOL CHILD; SECRETION; TREATMENT DURATION;

ADMINISTRATION, ORAL; AGED; ANIMALS; ANTIDIARRHEALS; CELL LINE; CELL MEMBRANE PERMEABILITY; CHILD; CHILD, PRESCHOOL; CHLORIDES; CHOLERA TOXIN; DIARRHEA; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; GASTROINTESTINAL TRACT; HT29 CELLS; HUMANS; INFANT; INTESTINAL SECRETIONS; MICE; MICE, INBRED C57BL; MIDDLE AGED; RETROSPECTIVE STUDIES; TANNINS; TREATMENT OUTCOME;

EID: 84856736757     PISSN: 01632116     EISSN: 15732568     Source Type: Journal    
DOI: 10.1007/s10620-011-1821-9     Document Type: Article

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