Upregulation of caveolin-1 expression is associated with structural modifications of endothelial cells in diabetic lung

Microvascular Research

Volumn 79, Issue 2, 2010, Pages 154-159

  Uyy, Elena ^a   Antohe, Felicia ^a   Ivan, Luminita ^a   Haraba, Raluca ^a   Radu, Dorel Lucian ^b   Simionescu, Maya ^a  

^a INSTITUTE OF CELLULAR BIOLOGY AND PATHOLOGY NICOLAE SIMIONESCU   (Romania)

^b CANTACUZINO INSTITUTE   (Romania)

Author keywords

Caveolae; Caveolae enriched membrane domains; Caveolin 1; Endothelial cell; Streptozotocin; Transgenic Diabetic mice; Type I diabetes mellitus

Indexed keywords

CAVEOLIN 1; CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE; STREPTOZOCIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL STRUCTURE; CELL TRANSFORMATION; CONTROLLED STUDY; DIABETES MELLITUS; ENDOTHELIUM CELL; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; HYPERGLYCEMIA; LIPID COMPOSITION; LUNG ENDOTHELIUM; MEMBRANE COMPONENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONTENT; STREPTOZOCIN DIABETES; UPREGULATION;

ANIMALS; CAVEOLIN 1; CELL FRACTIONATION; CELL SURFACE EXTENSIONS; CHOLESTEROL; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; GENE EXPRESSION; IMMUNOBLOTTING; LUNG; MALE; MICE; MICE, KNOCKOUT; PEPTIDYL-DIPEPTIDASE A; RNA, MESSENGER; UP-REGULATION;

MUS;

EID: 77049104512     PISSN: 00262862     EISSN: 10959319     Source Type: Journal    
DOI: 10.1016/j.mvr.2009.11.008     Document Type: Article

References (33)

1. Antohe F., Serban G., Radulescu L., and Simionescu M. Transcytosis of albumin in endothelial cells is Brefeldin A-independent. Endothelium. J. Endotoxin Res. 5 2 (1997) 125-136
2. Bucci M., Roviezzo F., Brancaleone V., Lin M.I., Di Lorenzo A., Cicala C., Pinto A., Sessa W.C., Farneti S., Fiorucci S., and Cirino G. Diabetic mouse angiopathy is linked to progressive sympathetic receptor deletion coupled to an enhanced caveolin-1 expression. Arteriosclerosis Thromb. Vasc. Biol. 24 (2004) 721-726
3. Burnier M., and Zanchi A. Blockade of the renin-angiotensin-aldosterone system: a key therapeutic strategy to reduce renal and cardiovascular events in patients with diabetes. J. Hypertens 24 (2006) 11-25
4. Coppey L.J., Gellett E.P., Davidson J.A., Dunlap J.A., and Lund D.D. Effect of antioxidant treatment of streptozocin-induced diabetic rats on endoneural blood flow, motor nerve conduction velocity, and vascular reactivity of epineurial arterioles of the sciatic nerve. Diabetes 50 (2001) 1927-1937
5. Degermann S., Reilly C., Scott B., Ogata L., von Boehmer H., and Lo D. On the various manifestations of spontaneous autoimmune diabetes in rodent models. Eur. J. Immunol. 24 12 (1994) 3155-3160
6. Drab M., Verkade P., Elger M., Kasper M., Lohn M., Lauterbach B., Menne J., Lindschau C., Mende F., Luft F.C., Schedl A., Haller H., and Kurzchalia T.V. Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. Science 293 (2001) 2449-2452
7. Erman A., van Dyk D.J., Chen-Gal B., Giler I.D., Rosenfeld J.B., and Boner G. Angiotensin converting enzyme activity in the serum, lung and kidney of diabetic rats. Eur. J. Clin. Invest. 23 (1993) 615-620
8. Hassan G.S., Jasmin J.F., Schubert W., Frank P.G., and Lisanti M.P. Caveolin-1 deficiency stimulates neointima formation during vascular injury. Biochemistry 43 26 (2004) 8312-8321
9. Heltianu C., Dobrila L., Antohe F., and Simionescu M. Evidence for thyroxine transport by the lung and heart capillary endothelium. Microvasc. Res. 37 2 (1989) 188-203
10. Hnasko R., and Lisanti M.P. The biology of caveolae: lessons from caveolin knockout mice and implications for human disease. Mol. Interv. 3 8 (2003) 445-464
11. Le P.U., Guay G., Altshuler Y., and Nabi I.R. Caveolin-1 is a negative regulator of caveolae mediated endocytosis to the endoplasmic reticulum. J. Biol. Chem. 277 (2002) 3371-3379
12. Like A.A., and Rossini A.A. Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science 193 4251 (1976) 415-417
13. Lisanti M.P., Scherer P., Tang Z.L., and Sargiacomo M. Caveolae, caveolin and caveolin-rich membrane domains: a signalling hypothesis. Trends Cell. Biol. 4 (1994) 231-235
14. Ljubić S., Metelko Z., Car N., Roglić G., and Drazić Z. Reduction of diffusion capacity for carbon monoxide in diabetic patients. Chest 114 4 (1998) 1033-1035
15. Mastick C.C., Brady M.J., and Saltiel A.R. Insulin stimulates the tyrosine phosphorylation of caveolin. J. Cell. Biol. 129 6 (1995) 1523-1531
16. Myint T., Hoshi S., Ookawara T., Miyazawa N., Suzuki K., and Taniguchi N. Immunological detection of glycated proteins in normal and streptozotocin-induced diabetic rats using anti-hexitol-lysine IgG. Biochim. Biophys. Acta 1272 (1995) 73-79
17. Oak J.H., and Cai H. Attenuation of angiotensin II signaling recouples eNOS and inhibits nonendothelial NOX activity in diabetic mice. Diabetes 56 (2007) 118-126
18. Ofulue A.F., Khadempour M.H., and Thurlbeck W.M. Diminished levels of insulin-like growth factor-I in lungs in streptozotocin-induced diabetes: relation to nutritional status and growth. Exp. Lung Res. 20 1 (1994) 27-40
19. Okamoto T., Schlegel A., Scherer P.E., and Lisanti M.P. Caveolins, a family of scaffolding proteins for organizing "preassembled signaling complexes" at the plasma membrane. J. Biol. Chem. 273 (1998) 5419-5422
20. Palade G.E. Fine structure of blood capillaries. J. Appl. Physiol. 24 (1953) 14-24
21. Pascariu M., Bendayan M., and Ghitescu L. Correlated endothelial caveolin overexpression and increased transcytosis in experimental diabetes. J. Histochem. Cytochem. 52 1 (2004) 65-76
22. Popov D., and Simionescu M. Structural and transport property alterations of the lung capillary endothelium in diabetes. Ital. J. Anat. Embryol 106 2 Suppl 1 (2001) 405-412
23. Radu D.L., Georgescu A., Stavaru C., Carale A., and Popov D. Double transgenic mice with type 1 diabetes mellitus develop somatic, metabolic and vascular disorders. J. Cell. Mol. Med. 8 3 (2004) 349-358
24. Razani B., and Lisanti M.P. Caveolins and caveolae: molecular and functional relationships. Exp. Cell. Res. 271 1 (2001) 36-44
25. Razani B., Woodman S.E., and Lisanti M.P. Caveolae: from cell biology to animal physiology. Pharmacol. Rev. 54 3 (2002) 431-467
26. Sargiacomo M., Sudol M., Tang Z.L., and Lisanti M.P. Signal transducing molecules and GPI-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J. Cell Biol. 122 (1993) 789-807
27. Scano G., Seghieri G., Mancini M., Filippelli M., Duranti R., Fabbri A., Innocenti F., Iandelli I., and Misuri G. Dispnoea, peripheral airway involvement and respiratory muscle effort in patients with type I diabetes mellitus under good metabolic control. Clin. Sci. 96 (1999) 499-506
28. Schwencke C., Schmeisser A., Walter C., Wachter R., Pannach S., Weck B., Braun-Dullaeus R.C., Kasper M., and Strasser R.H. Decreased caveolin-1 in atheroma: loss of antiproliferative control of vascular smooth muscle cells in atherosclerosis. Cardiovasc. Res. 168 1 (2005) 128-135
29. Simionescu N., Simionescu M., and Palade G.E. Permeability of muscle capillaries to small heme-peptides: evidence for existence of patent transendothelial channels. J. Cell. Biol. 64 (1975) 586-607
30. Simionescu M., Gafencu A., and Antohe F. Transcytosis of plasma macromolecules in endothelial cells: a cell biological survey. Microsc. Res. Tech. 57 5 (2002) 269-288
31. Thomsen P., Roepstor V.K., Stahlhut M., and Deurs B.V. Caveolae are highly immobile plasma membrane microdomains, which are not involved in constitutive endocytic trafficking. Mol. Biol. Cell 13 (2002) 238-250
32. Wasan K.M., Ng S.P., Wong W., and Rodrigues B.B. Streptozotocin- and alloxan-induced diabetes modifies total plasma and lipoprotein lipid concentration and composition without altering cholesteryl ester transfer activity. Pharmacol. Toxicol. 83 (1998) 169-175
33. Widlansky M.E., Gokce Jr. N., Keaney J.F., and Vita J.A. The clinical implications of endothelial dysfunction. J. Am. Coll. Cardiol. 42 7 (2003) 1149-1160