Disruption of the association of integrin-associated protein (IAP) with tyrosine phosphatase non-receptor type substrate-1 (SHPS)-1 inhibits pathophysiological changes in retinal endothelial function in a rat model of diabetes

Diabetologia

Volumn 55, Issue 3, 2012, Pages 835-844

  Maile, L A ^a   Gollahon, K ^a   Wai, C ^a   Byfield, G ^a   Hartnett, M E ^b   Clemmons, D ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Diabetic retinopathy; Hyperglycaemia; Hypoxia; Insulin like growth factor I; Integrin associated protein; Neovascularisation; Occluding; Vascular permeability

Indexed keywords

CD47 ANTIGEN; GLUCOSE; PROTEIN TYROSINE PHOSPHATASE; SOMATOMEDIN C; TYROSINE PHOSPHATASE NON RECEPTOR TYPE SUBSTRATE 1; UNCLASSIFIED DRUG; VASCULOTROPIN;

ANIMAL TISSUE; ARTICLE; BINDING SITE; BLOOD VESSEL PERMEABILITY; CELL ADHESION; CELL FUNCTION; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DIABETIC RETINOPATHY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HYPERGLYCEMIA; HYPOXIA; IN VIVO STUDY; MALE; NEWBORN; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; RAT;

ANIMALS; ANIMALS, NEWBORN; ANTIGENS, CD47; CAPILLARY PERMEABILITY; CELL ADHESION; CELLS, CULTURED; DIABETIC RETINOPATHY; DISEASE MODELS, ANIMAL; ENDOTHELIUM, VASCULAR; HL-60 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INFANT, NEWBORN; INSULIN-LIKE GROWTH FACTOR I; LEUKOCYTES; MALE; NEOVASCULARIZATION, PATHOLOGIC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, IMMUNOLOGIC; RETINA; RETINAL VESSELS; RETINOPATHY OF PREMATURITY;

EID: 84856717783     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2416-x     Document Type: Article

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