메뉴 건너뛰기




Volumn 31, Issue 2, 2012, Pages 193-198

Evidence of association between Methylenetetrahydrofolate Reductase gene and susceptibility to breast cancer: A candidate-gene association study in a South-Eastern European population

Author keywords

[No Author keywords available]

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2);

EID: 84856715687     PISSN: 10445498     EISSN: 15577430     Source Type: Journal    
DOI: 10.1089/dna.2011.1292     Document Type: Article
Times cited : (21)

References (43)
  • 1
    • 77957568513 scopus 로고    scopus 로고
    • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population
    • Antoniou, A.C., Wang, X., Fredericksen, Z.S., McGuffog, L., Tarrell, R., Sinilnikova, O.M., Healey, S., Morrison, J., Kartsonaki, C., Lesnick, T., et al. (2010). A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population. Nat Genet 42, 885-892.
    • (2010) Nat Genet , vol.42 , pp. 885-892
    • Antoniou, A.C.1    Wang, X.2    Fredericksen, Z.S.3    McGuffog, L.4    Tarrell, R.5    Sinilnikova, O.M.6    Healey, S.7    Morrison, J.8    Kartsonaki, C.9    Lesnick, T.10
  • 2
    • 0242610822 scopus 로고    scopus 로고
    • Folate, Methyl-Related Nutrients, Alcohol, and the MTHFR 677C→T Polymorphism Affect Cancer Risk: Intake Recommendations
    • Bailey, L.B. (2003). Folate, methyl-related nutrients, alcohol, and the MTHFR 677C-> T polymorphism affect cancer risk: intake recommendations. J Nutr 133, 3748S-3753S. (Pubitemid 37392595)
    • (2003) Journal of Nutrition , vol.133 , Issue.11 SUPPL. 1
    • Bailey, L.B.1
  • 5
    • 0035922669 scopus 로고    scopus 로고
    • Epidemiological methods for studying genes and environmental factors in complex diseases
    • DOI 10.1016/S0140-6736(01)06418-2
    • Clayton, D., and McKeigue, P.M. (2001). Epidemiological methods for studying genes and environmental factors in complex diseases. Lancet 358, 1356-1360. (Pubitemid 33016504)
    • (2001) Lancet , vol.358 , Issue.9290 , pp. 1356-1360
    • Clayton, D.1    McKeigue, P.M.2
  • 7
    • 1542357618 scopus 로고    scopus 로고
    • Polymorphisms in the MTHFR gene are associated with breast cancer
    • DOI 10.1159/000076460
    • Ergul, E., Sazci, A., Utkan, Z., and Canturk, N.Z. (2003). Polymorphisms in the MTHFR gene are associated with breast cancer. Tumour Biol 24, 286-290. (Pubitemid 38327990)
    • (2003) Tumor Biology , vol.24 , Issue.6 , pp. 286-290
    • Ergul, E.1    Sazci, A.2    Utkan, Z.3    Canturk, N.Z.4
  • 13
  • 14
    • 0032704132 scopus 로고    scopus 로고
    • Folate and cancer prevention: A new medical application of folate beyond hyperhomocysteinemia and neural tube defects
    • Kim, Y.I. (1999). Folate and cancer prevention: a new medical application of folate beyond hyperhomocysteinemia and neural tube defects. Nutr Rev 57, 314-321.
    • (1999) Nutr Rev , vol.57 , pp. 314-321
    • Kim, Y.I.1
  • 15
    • 70249115596 scopus 로고    scopus 로고
    • Genome-wide association studies: Hypothesis-"free" or "engaged"?
    • Kitsios, G.D., and Zintzaras, E. (2009a). Genome-wide association studies: hypothesis-"free" or "engaged"? Transl Res 154, 161-164.
    • (2009) Transl Res , vol.154 , pp. 161-164
    • Kitsios, G.D.1    Zintzaras, E.2
  • 16
    • 68549092835 scopus 로고    scopus 로고
    • Genomic convergence of genome-wide investigations for complex traits
    • Kitsios, G.D., and Zintzaras, E. (2009b). Genomic convergence of genome-wide investigations for complex traits. Ann Hum Genet 73, 514-519.
    • (2009) Ann Hum Genet , vol.73 , pp. 514-519
    • Kitsios, G.D.1    Zintzaras, E.2
  • 17
    • 33751355257 scopus 로고    scopus 로고
    • Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk
    • DOI 10.1093/jnci/djj440
    • Lewis, S.J., Harbord, R.M., Harris, R., and Smith, G.D. (2006). Meta-analyses of observational and genetic association studies of folate intakes or levels and breast cancer risk. J Natl Cancer Inst 98, 1607-1622. (Pubitemid 44811644)
    • (2006) Journal of the National Cancer Institute , vol.98 , Issue.22 , pp. 1607-1622
    • Lewis, S.J.1    Harbord, R.M.2    Harris, R.3    Smith, G.D.4
  • 20
    • 0028856381 scopus 로고
    • Proportion of breast cancer cases in the United States explained by well-established risk factors
    • Madigan, M.P., Ziegler, R.G., Benichou, J., Byrne, C., and Hoover, R.N. (1995). Proportion of breast cancer cases in the United States explained by well-established risk factors. J Natl Cancer Inst 87, 1681-1685.
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1681-1685
    • Madigan, M.P.1    Ziegler, R.G.2    Benichou, J.3    Byrne, C.4    Hoover, R.N.5
  • 21
    • 84863980509 scopus 로고    scopus 로고
    • Current strategies in the search for low penetrance genes in cancer
    • Milne, R.L., and Benitez, J. (2008). Current strategies in the search for low penetrance genes in cancer. Histol Histopathol 23, 507-514. (Pubitemid 351552336)
    • (2008) Histology and Histopathology , vol.23 , Issue.4-6 , pp. 507-514
    • Milne, R.L.1    Benitez, J.2
  • 23
    • 77956190896 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: A meta-analysis from 41 studies with 16,480 cases and 22,388 controls
    • Qi, X., Ma, X., Yang, X., Fan, L., Zhang, Y., Zhang, F., Chen, L., Zhou, Y., and Jiang, J. (2010). Methylenetetrahydrofolate reductase polymorphisms and breast cancer risk: a meta-analysis from 41 studies with 16,480 cases and 22,388 controls. Breast Cancer Res Treat 123, 499-506.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 499-506
    • Qi, X.1    Ma, X.2    Yang, X.3    Fan, L.4    Zhang, Y.5    Zhang, F.6    Chen, L.7    Zhou, Y.8    Jiang, J.9
  • 25
    • 18944381751 scopus 로고    scopus 로고
    • SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphism loci
    • DOI 10.1038/sj.cr.7290272
    • Shi, Y.Y., and He, L. (2005). SHEsis, a powerful software platform for analyses of linkage disequilibrium, haplotype construction, and genetic association at polymorphismloci. Cell Res 15, 97-98. (Pubitemid 41653949)
    • (2005) Cell Research , vol.15 , Issue.2 , pp. 97-98
    • Shi, Y.Y.1    He, L.2
  • 26
    • 0035824180 scopus 로고    scopus 로고
    • Alcohol and breast cancer: Review of epidemiologic and experimental evidence and potential mechanisms
    • Singletary, K.W., and Gapstur, S.M. (2001). Alcohol and breast cancer: review of epidemiologic and experimental evidence and potential mechanisms. JAMA 286, 2143-2151. (Pubitemid 34044116)
    • (2001) Journal of the American Medical Association , vol.286 , Issue.17 , pp. 2143-2151
    • Singletary, K.W.1    Gapstur, S.M.2
  • 28
    • 33646234965 scopus 로고    scopus 로고
    • Are we ready for genome-wide association studies?
    • Thomas, D.C. (2006). Are we ready for genome-wide association studies? Cancer Epidemiol Biomarkers Prev 15, 595-598.
    • (2006) Cancer Epidemiol Biomarkers Prev , vol.15 , pp. 595-598
    • Thomas, D.C.1
  • 31
    • 0031687887 scopus 로고    scopus 로고
    • A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity
    • DOI 10.1006/mgme.1998.2714
    • Weisberg, I., Tran, P., Christensen, B., Sibani, S., and Rozen, R. (1998). A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity. Mol Genet Metab 64, 169-172. (Pubitemid 28453294)
    • (1998) Molecular Genetics and Metabolism , vol.64 , Issue.3 , pp. 169-172
    • Weisberg, I.1    Tran, P.2    Christensen, B.3    Sibani, S.4    Rozen, R.5
  • 32
    • 77956191116 scopus 로고    scopus 로고
    • MTHFR C677T polymorphism associated with breast cancer susceptibility: A meta-analysis involving 15,260 cases and 20,411 controls
    • Zhang, J., Qiu, L.X., Wang, Z.H., Wu, X.H., Liu, X.J., Wang, B.Y., and Hu, X.C. (2010). MTHFR C677T polymorphism associated with breast cancer susceptibility: a meta-analysis involving 15,260 cases and 20,411 controls. Breast Cancer Res Treat 123, 549-555.
    • (2010) Breast Cancer Res Treat , vol.123 , pp. 549-555
    • Zhang, J.1    Qiu, L.X.2    Wang, Z.H.3    Wu, X.H.4    Liu, X.J.5    Wang, B.Y.6    Hu, X.C.7
  • 33
    • 1242339716 scopus 로고    scopus 로고
    • Role of vitamins in the risk, prevention, and treatment of breast cancer
    • DOI 10.1097/00001703-200402000-00005
    • Zhang, S.M. (2004). Role of vitamins in the risk, prevention, and treatment of breast cancer. Curr Opin Obstet Gynecol 16, 19-25. (Pubitemid 38241538)
    • (2004) Current Opinion in Obstetrics and Gynecology , vol.16 , Issue.1 , pp. 19-25
    • Zhang, S.M.1
  • 34
    • 33645472458 scopus 로고    scopus 로고
    • Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: A meta-analysis
    • Zintzaras, E. (2006). Methylenetetrahydrofolate reductase gene and susceptibility to breast cancer: a meta-analysis. Clin Genet 69, 327-336.
    • (2006) Clin Genet , vol.69 , pp. 327-336
    • Zintzaras, E.1
  • 35
    • 75749094714 scopus 로고    scopus 로고
    • Genetic variants of homocysteine/folate metabolism pathway and risk of inflammatory bowel disease: A synopsis and meta-analysis of genetic association studies
    • Zintzaras, E. (2010a). Genetic variants of homocysteine/folate metabolism pathway and risk of inflammatory bowel disease: a synopsis and meta-analysis of genetic association studies. Biomarkers 15, 69-79.
    • (2010) Biomarkers , vol.15 , pp. 69-79
    • Zintzaras, E.1
  • 36
    • 77956184720 scopus 로고    scopus 로고
    • Impact of Hardy-Weinberg equilibrium deviation on allele-based risk effect of genetic association studies and meta-analysis
    • Zintzaras, E. (2010b). Impact of Hardy-Weinberg equilibrium deviation on allele-based risk effect of genetic association studies and meta-analysis. Eur J Epidemiol 25, 553-560.
    • (2010) Eur J Epidemiol , vol.25 , pp. 553-560
    • Zintzaras, E.1
  • 37
    • 78649500637 scopus 로고    scopus 로고
    • Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: A genetic association study and meta-analysis
    • Zintzaras, E., Grammatikou, M., Kitsios, G.D., Doxani, C., Zdoukopoulos, N., Papandreou, C., and Patrikidou, A. (2010). Polymorphisms of the endothelial nitric oxide synthase gene in breast cancer: a genetic association study and meta-analysis. J Hum Genet 55, 743-748.
    • (2010) J Hum Genet , vol.55 , pp. 743-748
    • Zintzaras, E.1    Grammatikou, M.2    Kitsios, G.D.3    Doxani, C.4    Zdoukopoulos, N.5    Papandreou, C.6    Patrikidou, A.7
  • 38
    • 12744274510 scopus 로고    scopus 로고
    • Heterogeneity testing in meta-analysis of genome searches
    • Zintzaras, E., and Ioannidis, J.P. (2005). Heterogeneity testing in meta-analysis of genome searches. Genet Epidemiol 28, 123-137.
    • (2005) Genet Epidemiol , vol.28 , pp. 123-137
    • Zintzaras, E.1    Ioannidis, J.P.2
  • 39
    • 37648998741 scopus 로고    scopus 로고
    • Meta-analysis for ranked discovery datasets: Theoretical framework and empirical demonstration for microarrays
    • Zintzaras, E., and Ioannidis, J.P. (2008). Meta-analysis for ranked discovery datasets: theoretical framework and empirical demonstration for microarrays. Comput Biol Chem 32, 38-46.
    • (2008) Comput Biol Chem , vol.32 , pp. 38-46
    • Zintzaras, E.1    Ioannidis, J.P.2
  • 40
    • 33847633836 scopus 로고    scopus 로고
    • Response to endothelial nitric oxide synthase polymorphisms and susceptibility to hypertension: Genotype versus haplotype analysis [3]
    • DOI 10.1161/01.HYP.0000251076.18254.ed, PII 0000426820070100000043
    • Zintzaras, E., Kitsios, G., and Stefanidis, I. (2007). Response to endothelial nitric oxide synthase polymorphisms and susceptibility to hypertension: genotype versus haplotype analysis. Hypertension 49, E2. (Pubitemid 46360368)
    • (2007) Hypertension , vol.49 , Issue.1
    • Zintzaras, E.1    Kitsios, G.2    Stefanidis, I.3
  • 41
    • 69949114882 scopus 로고    scopus 로고
    • Synopsis and synthesis of candidate-gene association studies in chronic lymphocytic leukemia: The CUMAGAS-CLL information system
    • Zintzaras, E., and Kitsios, G.D. (2009). Synopsis and synthesis of candidate-gene association studies in chronic lymphocytic leukemia: the CUMAGAS-CLL information system. Am J Epidemiol 170, 671-678.
    • (2009) Am J Epidemiol , vol.170 , pp. 671-678
    • Zintzaras, E.1    Kitsios, G.D.2
  • 42
    • 39149139125 scopus 로고    scopus 로고
    • Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches
    • DOI 10.1016/j.jclinepi.2007.12.011, PII S0895435608000085
    • Zintzaras, E., and Lau, J. (2008a). Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches. J Clin Epidemiol 61, 634-645. (Pubitemid 351766746)
    • (2008) Journal of Clinical Epidemiology , vol.61 , Issue.7 , pp. 634-645
    • Zintzaras, E.1    Lau, J.2
  • 43
    • 37549016052 scopus 로고    scopus 로고
    • Trends in meta-analysis of genetic association studies
    • Zintzaras, E., and Lau, J. (2008b). Trends in meta-analysis of genetic association studies. J Hum Genet 53, 1-9.
    • (2008) J Hum Genet , vol.53 , pp. 1-9
    • Zintzaras, E.1    Lau, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.