-
1
-
-
0034758045
-
Genomewide scans of complex human diseases: True linkage is hard to find
-
Altmuller, J., Palmer, L. J., Fischer, G., Scherb, H. & Wjst, M. (2001) Genomewide scans of complex human diseases: True linkage is hard to find. Am J Hum Genet 69, 936-950.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 936-950
-
-
Altmuller, J.1
Palmer, L.J.2
Fischer, G.3
Scherb, H.4
Wjst, M.5
-
2
-
-
33845892752
-
Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database
-
Bertram, L., McQueen, M. B., Mullin, K., Blacker, D. & Tanzi, R. E. (2007) Systematic meta-analyses of Alzheimer disease genetic association studies: The AlzGene database. Nat Genet 39, 17-23.
-
(2007)
Nat Genet
, vol.39
, pp. 17-23
-
-
Bertram, L.1
McQueen, M.B.2
Mullin, K.3
Blacker, D.4
Tanzi, R.E.5
-
3
-
-
33847189247
-
Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases?
-
Bourgain, C., Génin, E., Cox, N. & Clerget-Darpoux, F. (2007) Are genome-wide association studies all that we need to dissect the genetic component of complex human diseases? Eur J Hum Genet 15, 260-263.
-
(2007)
Eur J Hum Genet
, vol.15
, pp. 260-263
-
-
Bourgain, C.1
Génin, E.2
Cox, N.3
Clerget-Darpoux, F.4
-
4
-
-
44349132708
-
Common and rare variants in multifactorial susceptibility to common diseases
-
Bodmer, W. & Bonilla, C. (2008) Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet 40, 695-701.
-
(2008)
Nat Genet
, vol.40
, pp. 695-701
-
-
Bodmer, W.1
Bonilla, C.2
-
5
-
-
0032231877
-
Comprehensive human genetic maps: Individual and sex-specific variation in recombination
-
Broman, K. W., Murray, J. C., Sheffield, V. C., White, R. L. & Weber, J. L. (1998) Comprehensive human genetic maps: Individual and sex-specific variation in recombination. Am J Hum Genet 63, 861-869.
-
(1998)
Am J Hum Genet
, vol.63
, pp. 861-869
-
-
Broman, K.W.1
Murray, J.C.2
Sheffield, V.C.3
White, R.L.4
Weber, J.L.5
-
6
-
-
34548223196
-
Genetic and genomic insights into the molecular basis of atherosclerosis
-
Chen, Y., Rollins, J., Paigen, B. & Wang, X. (2007) Genetic and genomic insights into the molecular basis of atherosclerosis. Cell Metab 6, 164-179.
-
(2007)
Cell Metab
, vol.6
, pp. 164-179
-
-
Chen, Y.1
Rollins, J.2
Paigen, B.3
Wang, X.4
-
7
-
-
0037444214
-
Genomic convergence: Identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage
-
Hauser, M. A., Li, Y. J., Takeuchi, S., Walters, R., Noureddine, M., Maready, M., Darden, T., Hulette, C., Martin, E., Hauser, E., Xu, H., Schmechel, D., Stenger, J. E., Dietrich, F. & Vance, J. (2003). Genomic convergence: Identifying candidate genes for Parkinson's disease by combining serial analysis of gene expression and genetic linkage. Hum Mol Genet 12, 671-677.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 671-677
-
-
Hauser, M.A.1
Li, Y.J.2
Takeuchi, S.3
Walters, R.4
Noureddine, M.5
Maready, M.6
Darden, T.7
Hulette, C.8
Martin, E.9
Hauser, E.10
Xu, H.11
Schmechel, D.12
Stenger, J.E.13
Dietrich, F.14
Vance, J.15
-
8
-
-
65949104586
-
Genomewide association studies and human disease
-
Hardy, J. & Singleton, A. (2009) Genomewide association studies and human disease. N Engl J Med 360, 1759-1768.
-
(2009)
N Engl J Med
, vol.360
, pp. 1759-1768
-
-
Hardy, J.1
Singleton, A.2
-
9
-
-
58049217860
-
-
Available at: Accessed at 11-15-2008
-
Hindorff, L. A., Junkins, H. A., Mehta, J. P. & Manolio, T. A. (2008). A Catalog of Published Genome-Wide Association Studies. Available at: http://www.genome.gov/26525384. Accessed at 11-15-2008.
-
(2008)
A Catalog of Published Genome-Wide Association Studies
-
-
Hindorff, L.A.1
Junkins, H.A.2
Mehta, J.P.3
Manolio, T.A.4
-
10
-
-
33846045494
-
T1DBase: Integration and presentation of complex data for type 1 diabetes research
-
Hulbert, E. M., Smink, L. J., Adlem, E. C., Allen, J. E., Burdick, D. B., Burren, O. S., Cassen, V. M., Cavnor, C. C., Dolman, G. E., Flamez, D., Friery, K. F., Healy, B. C., Killcoyne, S. A., Kutlu, B., Schuilenburg, H., Walker, N. M., Mychaleckyj, J., Eizirik, D. L., Wicker, L. S., Todd, J. A. & Goodman, N. (2007) T1DBase: Integration and presentation of complex data for type 1 diabetes research. Nucleic Acids Res 35, D742-746.
-
(2007)
Nucleic Acids Res
, vol.35
-
-
Hulbert, E.M.1
Smink, L.J.2
Adlem, E.C.3
Allen, J.E.4
Burdick, D.B.5
Burren, O.S.6
Cassen, V.M.7
Cavnor, C.C.8
Dolman, G.E.9
Flamez, D.10
Friery, K.F.11
Healy, B.C.12
Killcoyne, S.A.13
Kutlu, B.14
Schuilenburg, H.15
Walker, N.M.16
Mychaleckyj, J.17
Eizirik, D.L.18
Wicker, L.S.19
Todd, J.A.20
Goodman, N.21
more..
-
11
-
-
45949099964
-
From Darwin's finches to canaries in the coal mine-mining the genome for new biology
-
Hunter, D. J., Altshuler, D. & Rader, D. J. (2008) From Darwin's finches to canaries in the coal mine-mining the genome for new biology. N Engl J Med 358, 2760-2763.
-
(2008)
N Engl J Med
, vol.358
, pp. 2760-2763
-
-
Hunter, D.J.1
Altshuler, D.2
Rader, D.J.3
-
12
-
-
58949097433
-
CANDID: A flexible method for prioritizing candidate genes for complex human traits
-
Hutz, J. E., Kraja, A. T., McLeod, H. L. & Province, M. A. (2008) CANDID: A flexible method for prioritizing candidate genes for complex human traits. Genet Epidemiol 32, 779-790.
-
(2008)
Genet Epidemiol
, vol.32
, pp. 779-790
-
-
Hutz, J.E.1
Kraja, A.T.2
McLeod, H.L.3
Province, M.A.4
-
13
-
-
34447129720
-
Non-replication and inconsistency in the genome-wide association setting
-
Ioannidis, J. P. (2007) Non-replication and inconsistency in the genome-wide association setting. Hum Hered 64, 203-213.
-
(2007)
Hum Hered
, vol.64
, pp. 203-213
-
-
Ioannidis, J.P.1
-
14
-
-
36549036104
-
The genetic basis of complex traits: Rare variants or "common gene, common disease"?
-
Iyengar, S. K. & Elston, R. C. (2007) The genetic basis of complex traits: Rare variants or "common gene, common disease"? Methods Mol Biol 376, 71-84.
-
(2007)
Methods Mol Biol
, vol.376
, pp. 71-84
-
-
Iyengar, S.K.1
Elston, R.C.2
-
15
-
-
51449110541
-
A searchable database of genetic evidence for psychiatric disorders
-
Konneker, T., Barnes, T., Furberg, H., Losh, M., Bulik, C. M. & Sullivan, P. F. (2008) A searchable database of genetic evidence for psychiatric disorders. Am J Med Genet B Neuropsychiatr Genet 147B, 671-675.
-
(2008)
Am J Med Genet B Neuropsychiatr Genet
, vol.147 B
, pp. 671-675
-
-
Konneker, T.1
Barnes, T.2
Furberg, H.3
Losh, M.4
Bulik, C.M.5
Sullivan, P.F.6
-
16
-
-
8844280819
-
A combined linkage-physical map of the human genome
-
Kong, X., Murphy, K., Raj, T., He, C., White, P. S. & Matice, T. C. (2004) A combined linkage-physical map of the human genome. Am J Hum Genet 75, 1143-1148.
-
(2004)
Am J Hum Genet
, vol.75
, pp. 1143-1148
-
-
Kong, X.1
Murphy, K.2
Raj, T.3
He, C.4
White, P.S.5
Matice, T.C.6
-
17
-
-
41549126540
-
On the replication of genetic associations: Timing can be everything!
-
Lasky-Su, J., Lyon, H. N., Emilsson, V., Heid, I. M., Molony, C., Raby, B. A., Lazarus, R., Klanderman, B., Soto-Quiros, M. E., Avila, L., Silverman, E. K., Thorleifsson, G., Thorsteinsdottir, U., Kronenberg, F., Vollmert, C., Illig, T., Fox, C. S., Levy, D., Laird, N., Ding, X., McQueen, M. B., Butler, J., Ardlie, K., Papoutsakis, C., Dedoussis, G., O"Donnell, C. J., Wichmann, H. E., Celedón, J. C., Schadt, E., Hirschhorn, J., Weiss, S. T., Stefansson, K. & Lange, C. (2008) On the replication of genetic associations: Timing can be everything! Am J Hum Genet 82, 849-858.
-
(2008)
Am J Hum Genet
, vol.82
, pp. 849-858
-
-
Lasky-Su, J.1
Lyon, H.N.2
Emilsson, V.3
Heid, I.M.4
Molony, C.5
Raby, B.A.6
Lazarus, R.7
Klanderman, B.8
Soto-Quiros, M.E.9
Avila, L.10
Silverman, E.K.11
Thorleifsson, G.12
Thorsteinsdottir, U.13
Kronenberg, F.14
Vollmert, C.15
Illig, T.16
Fox, C.S.17
Levy, D.18
Laird, N.19
Ding, X.20
McQueen, M.B.21
Butler, J.22
Ardlie, K.23
Papoutsakis, C.24
Dedoussis, G.25
O'Donnell, C.J.26
Wichmann, H.E.27
Celedón, J.C.28
Schadt, E.29
Hirschhorn, J.30
Weiss, S.T.31
Stefansson, K.32
Lange, C.33
more..
-
18
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller, K. E., Pearce, C. L., Pike, M., Lander, E. S. & Hirschhorn, J. N. (2003) Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33, 177-182.
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
19
-
-
42349112088
-
Genome-wide association studies for complex traits: Consensus, uncertainty and challenges
-
McCarthy, M. I., Abecasis, G. R., Cardon, L. R., Goldstein, D. B., Little, J., Ioannidis, J. P. & Hirschhorn, J. N. (2008). Genome-wide association studies for complex traits: Consensus, uncertainty and challenges. Nat Rev Genet 9, 356-369.
-
(2008)
Nat Rev Genet
, vol.9
, pp. 356-369
-
-
McCarthy, M.I.1
Abecasis, G.R.2
Cardon, L.R.3
Goldstein, D.B.4
Little, J.5
Ioannidis, J.P.6
Hirschhorn, J.N.7
-
20
-
-
34247144499
-
Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study
-
Morgan, T. M., Krumholz, H. M., Lifton, R. P. & Spertus, J. A. (2007) Nonvalidation of reported genetic risk factors for acute coronary syndrome in a large-scale replication study. JAMA 297, 1551-1561.
-
(2007)
JAMA
, vol.297
, pp. 1551-1561
-
-
Morgan, T.M.1
Krumholz, H.M.2
Lifton, R.P.3
Spertus, J.A.4
-
21
-
-
34249997024
-
Replicating genotype-phenotype associations
-
NCI-NHGRI Working Group on Replication in Association Studies
-
NCI-NHGRI Working Group on Replication in Association Studies, Chanock, S. J., Manolio, T., Boehnke, M., Boerwinkle, E., Hunter, D. J., Thomas, G., Hirschhorn, J. N., Abecasis, G., Altshuler, D., Bailey-Wilson, J. E., Brooks, L. D., Cardon, L. R., Daly, M., Donnelly, P., Fraumeni, J. F. Jr., Freimer, N. B., Gerhard, D. S., Gunter, C., Guttmacher, A. E., Guyer, M. S., Harris, E. L., Hoh, J., Hoover, R., Kong, C. A., Merikangas, K. R., Morton, C. C., Palmer, L. J., Phimister, E. G., Rice, J. P., Roberts, J., Rotimi, C., Tucker, M. A., Vogan, K. J., Wacholder, S., Wijsman, E. M., Winn, D. M. & Collins, F. S. (2007) Replicating genotype-phenotype associations. Nature 447, 655-660.
-
(2007)
Nature
, vol.447
, pp. 655-660
-
-
Chanock, S.J.1
Manolio, T.2
Boehnke, M.3
Boerwinkle, E.4
Hunter, D.J.5
Thomas, G.6
Hirschhorn, J.N.7
Abecasis, G.8
Altshuler, D.9
Bailey-Wilson, J.E.10
Brooks, L.D.11
Cardon, L.R.12
Daly, M.13
Donnelly, P.14
Fraumeni Jr., J.F.15
Freimer, N.B.16
Gerhard, D.S.17
Gunter, C.18
Guttmacher, A.E.19
Guyer, M.S.20
Harris, E.L.21
Hoh, J.22
Hoover, R.23
Kong, C.A.24
Merikangas, K.R.25
Morton, C.C.26
Palmer, L.J.27
Phimister, E.G.28
Rice, J.P.29
Roberts, J.30
Rotimi, C.31
Tucker, M.A.32
Vogan, K.J.33
Wacholder, S.34
Wijsman, E.M.35
Winn, D.M.36
Collins, F.S.37
more..
-
22
-
-
40949127393
-
How to interpret a genome-wide association study
-
Pearson, T. A. & Manolio, T. A. (2008) How to interpret a genome-wide association study. JAMA 299, 1335-1344.
-
(2008)
JAMA
, vol.299
, pp. 1335-1344
-
-
Pearson, T.A.1
Manolio, T.A.2
-
23
-
-
33749017409
-
The human obesity gene map: The 2005 update
-
Rankinen, T., Zuberi, A., Chagnon, Y. C., Weisnagel, S. J., Argyropoulos, G., Walts, B., Pérusse, L. & Bouchard, C. (2006) The human obesity gene map: The 2005 update. Obesity(Silver.Spring) 14, 529-644.
-
(2006)
Obesity(Silver.Spring)
, vol.14
, pp. 529-644
-
-
Rankinen, T.1
Zuberi, A.2
Chagnon, Y.C.3
Weisnagel, S.J.4
Argyropoulos, G.5
Walts, B.6
Pérusse, L.7
Bouchard, C.8
-
24
-
-
31544449191
-
Using linkage genome scans to improve power of association in genome scans
-
Roeder, K., Bacanu, S. A., Wasserman, L. & Devlin, B. (2006) Using linkage genome scans to improve power of association in genome scans. Am J Hum Genet 78, 243-252.
-
(2006)
Am J Hum Genet
, vol.78
, pp. 243-252
-
-
Roeder, K.1
Bacanu, S.A.2
Wasserman, L.3
Devlin, B.4
-
25
-
-
0030966815
-
Empirical genomewide significance levels established by whole genome simulations
-
Sawcer, S., Jones, H. B., Judge, D., Visser, F., Compston, A., Goodfellow, P. N. & Clayton, D. (1997) Empirical genomewide significance levels established by whole genome simulations. Genet Epidemiol 14, 223-229.
-
(1997)
Genet Epidemiol
, vol.14
, pp. 223-229
-
-
Sawcer, S.1
Jones, H.B.2
Judge, D.3
Visser, F.4
Compston, A.5
Goodfellow, P.N.6
Clayton, D.7
-
26
-
-
0035173378
-
dbSNP: The NCBI database of genetic variation
-
Sherry, S. T., Ward, M. H., Kholodov, M., Baker, J., Phan, L., Smigielski, E. M. & Sirotkin, K. (2001) dbSNP: The NCBI database of genetic variation. Nucleic Acids Res 29, 308-311.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 308-311
-
-
Sherry, S.T.1
Ward, M.H.2
Kholodov, M.3
Baker, J.4
Phan, L.5
Smigielski, E.M.6
Sirotkin, K.7
-
27
-
-
40249113345
-
Commonality of functional annotation: A method for prioritization of candidate genes from genome-wide linkage studies
-
Shriner, D., Baye, T. M., Padilla, M. A., Zhang, S., Vaughan, L. K. & Loraine, A. E. (2008) Commonality of functional annotation: A method for prioritization of candidate genes from genome-wide linkage studies. Nucleic Acids Res 36, e26.
-
(2008)
Nucleic Acids Res
, vol.36
-
-
Shriner, D.1
Baye, T.M.2
Padilla, M.A.3
Zhang, S.4
Vaughan, L.K.5
Loraine, A.E.6
-
28
-
-
34347408099
-
Problems with genome-wide association studies
-
Shriner, D., Vaughan, L. K., Padilla, M. A. & Tiwari, H. K. (2007) Problems with genome-wide association studies. Science 316, 1840-1842.
-
(2007)
Science
, vol.316
, pp. 1840-1842
-
-
Shriner, D.1
Vaughan, L.K.2
Padilla, M.A.3
Tiwari, H.K.4
-
29
-
-
79959503826
-
-
The International HapMap Project
-
The International HapMap Project. (2003) Nature 426, 789-796.
-
(2003)
Nature
, vol.426
, pp. 789-796
-
-
-
30
-
-
38649091333
-
A navigator for human genome epidemiology
-
Yu, W., Gwinn, M., Clyne, M., Yesupriya, A. & Khoury, M. J. (2008) A navigator for human genome epidemiology. Nat Genet 40, 124-125.
-
(2008)
Nat Genet
, vol.40
, pp. 124-125
-
-
Yu, W.1
Gwinn, M.2
Clyne, M.3
Yesupriya, A.4
Khoury, M.J.5
-
31
-
-
34548187288
-
Genome-wide scans meta-analysis for pulse pressure
-
Zintzaras, E., Kitsios, G., Kent, D., Camp, N. J., Atwood, L., Hopkins, P. N. & Hunt, S. C. (2007) Genome-wide scans meta-analysis for pulse pressure. Hypertension 50, 557-564.
-
(2007)
Hypertension
, vol.50
, pp. 557-564
-
-
Zintzaras, E.1
Kitsios, G.2
Kent, D.3
Camp, N.J.4
Atwood, L.5
Hopkins, P.N.6
Hunt, S.C.7
-
32
-
-
39149139125
-
Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches
-
Zintzaras, E. & Lau, J. (2008) Synthesis of genetic association studies for pertinent gene-disease associations requires appropriate methodological and statistical approaches. J Clin Epidemiol 61, 634-645.
-
(2008)
J Clin Epidemiol
, vol.61
, pp. 634-645
-
-
Zintzaras, E.1
Lau, J.2
|