Optimization of human tendon tissue engineering: Synergistic effects of growth factors for use in tendon scaffold repopulation

Plastic and Reconstructive Surgery

Volumn 129, Issue 2, 2012, Pages 479-489

  Raghavan, Shyam S ^a   Woon, Colin Y L ^a   Kraus, Armin ^a   Megerle, Kai ^a   Pham, Hung ^a   Chang, James ^a  

^a STANFORD UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; PLATELET DERIVED GROWTH FACTOR B; PLATELET DERIVED GROWTH FACTOR BB; PLATELET-DERIVED GROWTH FACTOR BB; SOMATOMEDIN C; TISSUE SCAFFOLD;

ADIPOSE TISSUE; ARTICLE; CELL CULTURE; CYTOLOGY; DRUG EFFECT; DRUG POTENTIATION; FIBROBLAST; HUMAN; METHODOLOGY; STEM CELL; TENDON; TISSUE ENGINEERING;

ADIPOSE TISSUE; CELLS, CULTURED; DRUG SYNERGISM; FIBROBLAST GROWTH FACTOR 2; FIBROBLASTS; HUMANS; INSULIN-LIKE GROWTH FACTOR I; PROTO-ONCOGENE PROTEINS C-SIS; STEM CELLS; TENDONS; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84856692220     PISSN: 00321052     EISSN: None     Source Type: Journal    
DOI: 10.1097/PRS.0b013e31823aeb94     Document Type: Article

References (42)

1. Zhang AY, Bates SJ, Morrow E, Pham H, Pham B, Chang J. Tissue-engineered intrasynovial tendons: Optimization of acellularization and seeding. J Rehabil Res Dev. 2009;46:489-498.
2. Zhang AY, Chang J. Tissue engineering of flexor tendons. Clin Plast Surg. 2003;30:565-572.
3. Chong AK, Chang J. Tissue engineering for the hand surgeon: A clinical perspective. J Hand Surg Am. 2006;31:349-358.
4. Leversedge FJ, Zelouf D, Williams C, Gelberman RH, Seiler JG III. Flexor tendon grafting to the hand: An assessment of the intrasynovial donor tendon-A preliminary single-cohort study. J Hand Surg Am. 2000;25:721-730.
5. Rosberg HE, Carlsson KS, Höjgård S, Lindgren B, Lundborg G, Dahlin LB. What determines the costs of repair and rehabilitation of flexor tendon injuries in zone II? A multiple regression analysis of data from southern Sweden. J Hand Surg Br. 2003;28:106-112.
6. Pridgen B, Woon C, Kim M, et al. Flexor tendon tissue engineering: Acellularization of human flexor tendons with preservation of biomechanical properties and biocompatibility. Tissue Eng Part C Methods 2011;17:819-828.
7. Chong AK, Riboh J, Smith RL, Lindsey DP, Pham HM, Chang J. Flexor tendon tissue engineering: Acellularized and reseeded tendon constructs. Plast Reconstr Surg. 2009;123:1759-1766.
8. Woon CY, Pridgen BC, Kraus A, Bari S, Pham H, Chang J. Optimization of human tendon tissue engineering: Peracetic acid oxidation for enhanced reseeding of acellularized intrasynovial tendon. Plast Reconstr Surg. 2011;127:1107-1117.
9. Saber S, Zhang AY, Ki SH, et al. Flexor tendon tissue engineering: Bioreactor cyclic strain increases construct strength. Tissue Eng Part A 2010;16:2085-2090.
10. Butler DL, Juncosa-Melvin N, Boivin GP, et al. Functional tissue engineering for tendon repair: A multidisciplinary strategy using mesenchymal stem cells, bioscaffolds, and mechanical stimulation. J Orthop Res. 2008;26:1-9.
11. Angelidis IK, Thorfinn J, Connolly ID, Lindsey D, Pham HM, Chang J. Tissue engineering of flexor tendons: The effect of a tissue bioreactor on adipoderived stem cell-seeded and fibroblast-seeded tendon constructs. J Hand Surg Am. 2010; 35:1466-1472.
12. James R, Kesturu G, Balian G, Chhabra AB. Tendon: Biology, biomechanics, repair, growth factors, and evolving treatment options. J Hand Surg Am. 2008;33:102-112.
13. Riboh J, Chong AK, Pham H, Longaker M, Jacobs C, Chang J. Optimization of flexor tendon tissue engineering with a cyclic strain bioreactor. J Hand Surg Am. 2008;33:1388-1396.
14. Kryger GS, Chong AK, Costa M, Pham H, Bates SJ, Chang J. A comparison of tenocytes and mesenchymal stem cells for use in flexor tendon tissue engineering. J Hand Surg Am. 2007;32:597-605.
15. Thorfinn J, Saber S, Angelidis IK, et al. Flexor tendon tissue engineering: Temporal distribution of donor tenocytes versus recipient cells. Plast Reconstr Surg. 2009;124:2019-2026.
16. Issa RI, Engebretson B, Rustom L, McFetridge PS, Sikavitsas VI. The effect of cell seeding density on the cellular and mechanical properties of a mechanostimulated tissue-engineered tendon. Tissue Eng Part A 2011;17:1479-1487.
17. Liu CF, Aschbacher-Smith L, Barthelery NJ, Dyment N, Butler D, Wylie C. What we should know before using tissue engineering techniques to repair injured tendons: A developmental biology perspective. Tissue Eng Part B Rev. 2011; 17:165-176.
18. Hsu C, Chang J. Clinical implications of growth factors in flexor tendon wound healing. J Hand Surg Am. 2004;29:551-563.
19. Molloy T, Wang Y, Murrell G. The roles of growth factors in tendon and ligament healing. Sports Med. 2003;33:381-394.
20. Chang J, Most D, Thunder R, Mehrara B, Longaker MT, Lineaweaver WC. Molecular studies in flexor tendon wound healing: The role of basic fibroblast growth factor gene expression. J Hand Surg Am. 1998;23:1052-1058.
21. Chan BP, Chan KM, Maffulli N, Webb S, Lee KK. Effect of basic fibroblast growth factor: An in vitro study of tendon healing. Clin Orthop Relat Res. 1997;342:239-247.
22. Thomopoulos S, Harwood FL, Silva MJ, Amiel D, Gelberman RH. Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro. J Hand Surg Am. 2005;30:441-447.
23. Wang XT, Liu PY, Xin KQ, Tang JB. Tendon healing in vitro: BFGF gene transfer to tenocytes by adeno-associated viral vectors promotes expression of collagen genes. J Hand Surg Am. 2005;30:1255-1261.
24. Thomopoulos S, Das R, Sakiyama-Elbert S, Silva MJ, Charlton N, Gelberman RH. bFGF and PDGF-BB for tendon repair: Controlled release and biologic activity by tendon fibroblasts in vitro. Ann Biomed Eng. 2010;38:225-234.
25. Tang JB, Cao Y, Zhu B, Xin KQ, Wang XT, Liu PY. Adenoassociated virus-2-mediated bFGF gene transfer to digital flexor tendons significantly increases healing strength: An in vivo study. J Bone Joint Surg Am. 2008;90:1078-1089.
26. Ide J, Kikukawa K, Hirose J, et al. The effect of a local application of fibroblast growth factor-2 on tendon-to-bone remodeling in rats with acute injury and repair of the supraspinatus tendon. J Shoulder Elbow Surg. 2009;18:391-398.
27. Ide J, Kikukawa K, Hirose J, Iyama K, Sakamoto H, Mizuta H. The effects of fibroblast growth factor-2 on rotator cuff reconstruction with acellular dermal matrix grafts. Arthroscopy 2009;25:608-616.
28. Mueller RV, Hunt TK, Tokunaga A, Spencer EM. The effect of insulinlike growth factor I on wound healing variables and macrophages in rats. Arch Surg. 1994;129:262-265.
29. Banes AJ, Tsuzaki M, Hu P, et al. PDGF-BB, IGF-I and mechanical load stimulate DNA synthesis in avian tendon fibroblasts in vitro. J Biomech. 1995;28:1505-1513.
30. Tsuzaki M, Brigman BE, Yamamoto J, et al. Insulin-like growth factor-I is expressed by avian flexor tendon cells. J Orthop Res. 2000;18:546-556.
31. Dahlgren LA, Mohammed HO, Nixon AJ. Expression of insulin-like growth factor binding proteins in healing tendon lesions. J Orthop Res. 2006;24:183-192.
32. Suwalski A, Dabboue H, Delalande A, et al. Accelerated Achilles tendon healing by PDGF gene delivery with mesoporous silica nanoparticles. Biomaterials 2010;31:5237-5245.
33. Thomopoulos S, Das R, Silva MJ, et al. Enhanced flexor tendon healing through controlled delivery of PDGF-BB. J Orthop Res. 2009;27:1209-1215.
34. Klein MB, Yalamanchi N, Pham H, Longaker MT, Chang J. Flexor tendon healing in vitro: Effects of TGF-beta on tendon cell collagen production. J Hand Surg Am. 2002;27:615-620.
35. Bates SJ, Morrow E, Zhang AY, Pham H, Longaker MT, Chang J. Mannose-6-phosphate, an inhibitor of transforming growth factor-beta, improves range of motion after flexor tendon repair. J Bone Joint Surg Am. 2006;88:2465-2472.
36. Costa MA, Wu C, Pham BV, Chong AK, Pham HM, Chang J. Tissue engineering of flexor tendons: Optimization of tenocyte proliferation using growth factor supplementation. Tissue Eng. 2006;12:1937-1943.
37. Thomopoulos S, Das R, Sakiyama-Elbert S, Silva MJ, Charlton N, Gelberman RH. bFGF and PDGF-BB for tendon repair: Controlled release and biologic activity by tendon fibroblasts in vitro. Ann Biomed Eng. 2009;38:225-234.
38. Costa MA, Wu C, Pham BV, Chong AK, Pham HM, Chang J. Tissue engineering of flexor tendons: Optimization of tenocyte proliferation using growth factor supplementation. Tissue Eng. 2006;12:1937-1943.
39. Ingram JH, Korossis S, Howling G, Fisher J, Ingham E. The use of ultrasonication to aid recellularization of acellular natural tissue scaffolds for use in anterior cruciate ligament reconstruction. Tissue Eng. 2007;13:1561-1572.
40. Wendt D, Marsano A, Jakob M, Heberer M, Martin I. Oscillating perfusion of cell suspensions through three-dimensional scaffolds enhances cell seeding efficiency and uniformity. Biotechnol Bioeng. 2003;84:205-214.
41. de Mos M, van der Windt AE, Jahr H, et al. Can platelet-rich plasma enhance tendon repair? A cell culture study. Am J Sports Med. 2008;36:1171-1178.
42. Schnabel LV, Mohammed HO, Miller BJ, et al. Platelet rich plasma (PRP) enhances anabolic gene expression patterns in flexor digitorum superficialis tendons. J Orthop Res. 2007;25: 230-240.