Effect of endovenous morphine vs. ketorolac on proinflammatory cytokines during postoperative analgesia in laparoscopic cholecystectomy;Efecto de la analgesia posoperatoria de la morfina endovenosa versus el ketorolaco en citocinas proinflamatorias en colecistectomía laparoscópica

Cirugia y Cirujanos

Volumn 80, Issue 1, 2012, Pages 56-62

  Gómez Vázquez, María Elena ^a   Hernández Salazar, Eduardo ^a   Novelo Otañez, Jorge Daniel ^b   Cabrera Pivaral, Carlos Enrique ^b   Dávalos Rodríguez, Ingrid Patricia ^c   Salazar Páramo, Mario ^b  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^b HOSPITAL DE ESPECIALIDADES   (Mexico)

^c CENTRO DE INVESTIGACIÓN BIOMÉDICA DE OCCIDENTE   (Mexico)

Author keywords

Cytokines; Ketorolac; Morphine; Postoperative analgesia

Indexed keywords

ANALGESIC AGENT; INTERLEUKIN 1BETA; KETOROLAC; MORPHINE; NARCOTIC AGENT; NONSTEROID ANTIINFLAMMATORY AGENT; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD; CHEMICALLY INDUCED DISORDER; CHOLECYSTECTOMY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; INFLAMMATION; INTRAVENOUS DRUG ADMINISTRATION; MIDDLE AGED; PAIN ASSESSMENT; PATHOPHYSIOLOGY; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FAILURE; SECRETION;

ADULT; ANALGESICS, NON-NARCOTIC; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHOLECYSTECTOMY, LAPAROSCOPIC; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INFLAMMATION; INFUSIONS, INTRAVENOUS; INTERLEUKIN-1BETA; KETOROLAC; MIDDLE AGED; MORPHINE; NARCOTICS; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; POSTOPERATIVE COMPLICATIONS; POSTOPERATIVE HEMORRHAGE; POSTOPERATIVE NAUSEA AND VOMITING; RESPIRATORY INSUFFICIENCY; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84856682216     PISSN: 00097411     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. Mehigan BJ, Hartley JE, Drew PJ, Sale A, Dore PC, Lee PW, et al. Changes in cell subsets, interleukin-6 and C-reactive protein after laparoscopic and open colorectal resection for malignancy. Surg Endosc 2001; 5:1289-1293. (Pubitemid 33035405)
2. Roth-Isikeit A, Borstel TV, Seyfarth M. Perioperative serum levels of tumor necrosis factor alpha (TNF-α), IL1β, IL-6, IL-10 and soluble IL-2 receptor in patients undergoing cardiac surgery with cardiopulmonary bypass without and with correction for haemodilution. Clin Exp Immnol 1999; 118:242-246. (Pubitemid 29519254)
3. Beuder B, Cerami A. Cachectin: more than a tumor necrosis factor. N Engl J Med 1987; 316:379-385. (Pubitemid 17034263)
4. García V, López-Briz E. Morphine remains gold standard in breakthrough cancer pain. BMJ 2008; 316:379-385.
5. Chen JY, Wu GH, Mok MS, Chou YH, Sun WZ, Chen PL, et al. Effect of adding ketorolac to intravenous morphine patient-controlled analgesia on bowel function in colorectal surgery patients a prospective, randomized, double-blind study. Acta Anaesth Scand 2005; 49:546-551. (Pubitemid 40488579)
6. Lichtor J, Sevarino F. The relative potency of oral transmucosal fentanyl citrate compared with intravenous morphine in the treatment of moderate to severe postoperative pain. Anesth Analg 1999; 89:732-736.
7. Yoshida S, Ohta J, Yamasaki K, Kamei H, Harada Y, Yahara T, et al. Effect of surgical stress on endogenous morphine and cytokine levels in the plasma after laparoscopic or open cholecystectomy. Surg Endosc 2000; 14:137-140. (Pubitemid 30080262)
8. Ishizuka B, Kuribayashi Y, Hamada N, Abe Y, Amemiya A, Aoki T, et al. Stress responses during laparoscopy with CO2 insufflation and with mechanical elevation of the abdominal wall. J Am Assoc Gynecol Laparosc 2000; 3:363-371. (Pubitemid 32661603)
9. Mayburd E, Smirnov G, Dekel A, Yarden, Yehuda I. Effects of preemptive analgesia on pain and cytokine production in the postoperative period. Anesthesiology 2003; 98:151-155. (Pubitemid 36043421)
10. Bravo-Cuéllar A, Rodríguez-Romero JE, Hernández- Flores G, Romo-Pérez FJ. Comparación de dos técnicas anestésicas sobre los niveles plasmáticos de marcadores inflamatorios. Cir Cir 2007; 75:99-105.
11. Helmy AK, Ahhby MA, Nawaway E. The effect of anaesthesia and surgery on plasma cytokine production. Anaesthesia 1999; 54:733-738.
12. Hutchinson MR, Coats B, Lewis S, Sprunger Y, Rezvani N, Baker E, et al. Proinflammatory cytokines oppose opiod-induced acute and chronic analgesia. Brain Behav 2008; 22:1178-1189.
13. Schietroma M, Carlei F, Lezoche E, Agnifili A, Enang GN, Mattucci S, et al. Evaluation of immune response in patients after open or laparoscopic cholecystectomy. Hepatogastroenterology 2001; 48:6452-6646.
14. Schietroma M, Giuliani A, Agnifili A, Lely L, Carlei F, Pescosolido A, Amicucci G. Changes in blood coagulation, fibrinolysis, and cytokine profile during laparoscopic and open cholecystectomy. Surg Endosc 2004; 18:1090-1096. (Pubitemid 38918023)
15. Keats A. The ASA classification of physical statusA recapitulation. Anesthesiology 1978; 49:233-235.
16. Aldrete JA, Kroulik D. A postanesthesic store. Anesth Analg 1979; 49:294.
17. Revill SI, Robinson JO, Roses M. The reability of a linear analogue scale for evaluating pain. Anaesthesia 1976; 31:1191-1194.
18. Fletcher D, Pinaud M, Scherpereel, Clyti N, Chauvin M. The efficacy of intravenous 0.15 versus 0.25 mg/kg intraoperative morphine for inmediate postoperative analgesia after remifentanyl-based anesthesia for major surgery. Anesth Analg 2000; 90:666-671. (Pubitemid 30117529)
19. Buckley MM, Brogden RN. Ketorolac: a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential. Drugs 1990; 39:86-109.
20. Ramsay M, Sawage T, Simpson BR. Ramsay scale. Crit Care 2000; 4:225-227.
21. Daniel WW. Tablas Estadísticas. 4th ed. Mexico, D.F.: Limusa-Wiley; 2002. p. A-39.
22. Celis A. Tamaño de Muestra para Variables Dependientes Cuantitativas. México, D.F.: El Manual Moderno, 2005. pp. 185-189.
23. Sales VF. Cálculo del tamaño de la muestra. In: Moreno L, Cano F, Garcia H, eds. Epidemiología Clínica. 2nd ed. México: Interamericana McGraw-Hill, 1994. pp. 261-274.
24. Ley General de Salud en materia de investigación para la salud articulo Diario Oficial de la Federación México 2005. Disponible en www.leygeneralsalud.com.mx
25. Cann C, Curran J, Milner T. Unwanted effects of morphine-6-glucoronide and morphine. Anaesthesia 2002; 57:1200-1203.
26. Olofsen E, Van Dorp E, Teppema L, Aarts L, Smith T, Dahan A, et al. Naloxone reversal of morphine-6-glucoronide induced respiratory depression in healthy volunteers: a mechanism-based pharmacokinetic-pharmacodynamic modeling study. Anesthesiology 2010; 12:1417-1427.
27. Dahan A, Aarts L, Smith T. Incidence, reversal, and prevention of opiod-induced respiratory depression. Anesthesiology 2010; 12:226-238.
28. Arain S, Ruehlow R, Uhrich T, Ebert T. the efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg 2004:153-158. (Pubitemid 38029869)
29. Jacobbi CA, Ordemann J, Halle E, Volk HD, Muller JM A. Impact of laparoscopy with CO2 versus helium on local and systemic inflammation in an animal model of peritonitis J Laparoendosc Adv Surg Tech A 1999; 9:305-312.
30. Jakeways MS, Mitchel V, Hashim JA, Chadwick SJ, Shenkin A, Green CJ, et al. Metabolic and inflammatory responses after open or laparoscopic cholecystectomy. Br J Surg 1994; 6:127-131. (Pubitemid 24048963)
31. Sari R, Sevinc A. The effects of laparoscopic cholecystectomy operation on C-reactive protein, hormones and cytokines. J Endocrinol Invest 2004; 27:106-110. (Pubitemid 38514800)
32. Ordemann J, Jacobi CA, Schwenk W, Stösslein R, Müller JM. Cellular and humoral inflammatory response after laparoscopic and conventional colorectal resections. Surg Endosc 2001; 15:600-608. (Pubitemid 32500130)
33. Sáenz Medina J, Asuero de Lis MS, Villafruela Sánz J, Corres Gorospe C, Cuevas B, Galindo Alvarez J, et al. Immune response during laparoscopic and open living donor nephrectomy. An experimental pig model. Acta Urol Esp 2008; 32:435-442.
34. Lausten SB, Ibrahim TM, El-Sefi T, Jensen LS, Gesser B, Laersen CG, et al. Systemic and cell-mediated immune response after laparoscopic and open cholecystectomy in patients with chronic liver disease. Dig Surg 1999; 16:471-477. (Pubitemid 30072155)
35. Matsumoto ED, Margulis V, Tunc L, Taylor GD, Duchene D, Johnson DB, et al. Cytokine response to surgical stress. Comparison of pure laparoscopic, hand-assisted laparoscopic and open nephrectomy. J Endourol 2005; 19:1140-1145. (Pubitemid 41691731)
36. Clark JD, Shi X, Li X, Quiao Y, Lang D, Angst MS, et al. Morphine reduces local cytokine expression and neutrophil infiltration after incision. Mol Pain 2007; 3:28.
37. Bonnet MP, Beloeil H, Benhamou D, Mazoit JX, Asehnoune K. The mu opiod receptor mediates morphine-induced tumor necrosis factor and interleukin-6 inhibition in toll-like receptor 2-stimulated monocytes. Anesth Analg 2008; 106:1142-1149. (Pubitemid 351450539)
38. Johnston IN, Milligan ED, Wieseler-Frank J, Frank MG, Zapata V, Campisi J, et al. A role for proinflammatory cytokines and fractalkine in analgesia, tolerance, and subsequent pain facilitation induced by chronic intrathecal morphine. J Neurosci 2004; 24:7353-7365. (Pubitemid 39100704)
39. Raghavendra V, Tanga FY, DeLeo JA. Attenuation of morphine tolerance, withdrawal-induced hyperalgesia, and associated spinal inflammatory immune responses by propentofylline in rats. Neuropsychopharmacology 2004; 29:327-334. (Pubitemid 38175151)
40. Kim MH, Hahm TS. Plasma levels of interleukin-6 and interleukin-10 are affected by ketorolac as an adjunct to patient-controlled morphine after abdominal hysterectomy. Clin J Pain 2001; 17:72-77. (Pubitemid 32225168)