Synthesis and evaluation of a novel series of indoloisoquinolines as small molecule anti-malarial leads

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1770-1773

  Horrocks, Paul ^a   Fallon, Samantha ^a   Denman, Laura ^a   Devine, Oliver ^a   Duffy, Liam J ^a   Harper, Anthony ^a   Meredith, Emma Louise ^a   Hasenkamp, Sandra ^a   Sidaway, Adam ^a   Monnery, Daniel ^a   Phillips, Theresa R ^a   Allin, Steven M ^a  

^a KEELE UNIVERSITY   (United Kingdom)

Author keywords

Anti malarial; Dihydrousambarensine; Indoloisoquinoline; Malaria; Natural product

Indexed keywords

ANTIMALARIAL AGENT; DIHYDROUSAMBARENSINE; INDOLOISOQUINOLINE; ISOQUINOLINE DERIVATIVE; TRYPTOPHAN; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; CHIRALITY; DRUG SCREENING; DRUG SYNTHESIS; IC 50; NONHUMAN; PLASMODIUM FALCIPARUM; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

EID: 84856658685     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.071     Document Type: Article

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