Exogenous hydrogen sulfide (H 2S) reduces blood pressure and prevents the progression of diabetic nephropathy in spontaneously hypertensive rats

Renal Failure

Volumn 34, Issue 2, 2012, Pages 203-210

  Ahmad, Fiaz Ud Din ^a   Sattar, Munavvar Abdul ^a   Rathore, Hassaan Anwer ^a   Abdullah, Mohammed Hadi ^a   Tan, Samual ^a   Abdullah, Nor Azizan ^b   Johns, Edward James ^c  

^a SCHOOL OF PHARMACEUTICAL SCIENCES   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

Hydrogen sulfide; Nephropathy; Spontaneously hypertensive rats; Streptozotocin

Indexed keywords

CREATININE; ELECTROLYTE; HYDROGEN SULFIDE;

ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE; BLOOD PRESSURE MEASUREMENT; BODY WEIGHT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; DIABETIC NEPHROPATHY; DISEASE COURSE; ESSENTIAL HYPERTENSION; FLUID INTAKE; KIDNEY DYSFUNCTION; NONHUMAN; PRIORITY JOURNAL; RAT; RENAL PROTECTION; STREPTOZOCIN DIABETES; URINE FLOW RATE;

ANIMALS; BLOOD PRESSURE; DIABETIC NEPHROPATHIES; DISEASE PROGRESSION; HYDROGEN SULFIDE; HYPERTENSION; RATS; RATS, INBRED SHR; RATS, INBRED WKY;

EID: 84856630877     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.3109/0886022X.2011.643365     Document Type: Article

References (52)

1. National High Blood Pressure Education Program Working Group. Hypertension. 1994;23:145-158.
2. Contreras F, Rivera M, Vasquez J, De la Parte MA, Velasco M. Endothelial dysfunction in arterial hypertension. J Hum Hypertens. 2000;14:S20-S25. (Pubitemid 30406515)
3. Ogihara T, Asano T, Ando K, et al. Angiotensin II-induced insulin resistance is associated with enhanced insulin signaling. Hypertension. 2002;40:872-879. (Pubitemid 35434909)
4. Blendea MC, Jacobs D, Stump CS, et al. Abrogation of oxidative stress improves insulin sensitivity in the Ren-2 rat model of tissue angiotensin II overexpression. Am J Physiol Endocrinol Metab. 2005;288:E353-E359. (Pubitemid 40110643)
5. Sowers JR. Insulin resistance and hypertension. Am J Physiol Heart Circ Physiol. 2004;286:H1597-H1602. (Pubitemid 38525443)
6. McFarlane SI, Sowers JR. Special features- CARDIOVASCULAR ENDOCRINOLOGY 1: aldosterone function in diabetes mellitus-effects on cardiovascular and renal disease. J Clin Endocrinol Metab. 2003;88:516-523. (Pubitemid 36207783)
7. Wolf G. New insights into the pathophysiology of diabetic nephropathy: From hemodynamics to molecular pathology. Eur J Clin Invest. 2004;34:785-796. (Pubitemid 39657924)
8. Tesch GH, Allen TJ. Rodent models of streptozotocin induced diabetic nephropathy (methods in renal research). Nephrology. 2007;12:261-266. (Pubitemid 46718209)
9. Allen TJ, Cao Z, Youssef S, Hulthen UL, Cooper ME. Role of angiotensin II and bradykinin in experimental diabetic nephropathy. Functional and structural studies. Diabetes. 1997;46:1612-1618.
10. Cooper ME, Allen TJ, Jerums G, Doyle AE. Accelerated progression of diabetic nephropathy in the spontaneously hypertensive streptozotocin diabetic rat. Clin Exp Pharmacol Physiol. 1986;13:655-662. (Pubitemid 17229404)
11. Wang RUI. Twos company, threes a crowd: Can H2S be the third endogenous gaseous transmitter? FASEB J. 2002;16:1792-1798.
12. Zhao W, Zhang J, Lu Y, Wang R. The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener. EMBO J. 2001;20:6008-6016. (Pubitemid 33049276)
13. Stipanuk MH, Beck PW. Characterization of the enzymic capacity for cysteine desulphhydration in liver and kidney of the rat. Biochem J. 1982;206:267-277.
14. Levonen AL, Lapatto R, Saksela M, Raivio KO. Human cystathionine gamma-lyase: Developmental and in vitro expression of two isoforms. Biochem J. 2000;347:291-295. (Pubitemid 30199069)
15. Yan H, Du J, Tang C. The possible role of hydrogen sulfide on the pathogenesis of spontaneous hypertension in rats. Biochem Biophys Res Commun. 2004;313:22-27. (Pubitemid 37524019)
16. Yang Y, Geng X, Tang C. Hydrogen sulfide system in the pathogenesis of renovascular hypertension in rats. J Geriatr Cardiol. 2008;5:1-5.
17. Zhong GZ, Chen FR, Cheng YQ, Tang CS, Du JB. The role of hydrogen sulfide generation in the pathogenesis of hypertension in rats induced by inhibition of nitric oxide synthase. J Hypertens. 2003;21:1879-1885.
18. Yuan P, Xue H, Zhou L, et al. Rescue of mesangial cells from high glucose-induced over-proliferation and extracellular matrix secretion by hydrogen sulfide. Nephrol Dial Transplant. 2011;26(7):2119-2126.
19. Ramesh B, Pugalendi KV. Antioxidant role of umbelliferone in STZ-diabetic rats. Life Sci. 2006;79:306-310. (Pubitemid 43782543)
20. Suckow MA, Weisbroth SH, Franklin CL. The Laboratory Rat. Washington, DC: Academic Press; 2006:655.
21. Lee TN, Alborn WE, Knierman MD, Konrad RJ. The diabetogenic antibiotic streptozotocin modifies the tryptic digest pattern for peptides of the enzyme O-GlcNAc-selective N-acetyl-[beta]-d-glucosaminidase that contain amino acid residues essential for enzymatic activity. Biochem Pharmacol. 2006;72:710-718. (Pubitemid 44233547)
22. Wong KK, Tzeng ES. Appearance of different diabetic symptoms after streptozocin administration: A comparison study. Biochem Mol Biol Int. 1993;30:1035-1041. (Pubitemid 23276069)
23. XiaM, Chen L,Muh RW, Li PL, Li N. Production and actions of hydrogen sulfide, a novel gaseous bioactive substance, in the kidneys. J Pharmacol Exp Ther. 2009;329:1056-1062.
24. Thomson SC, Vallon V, Blantz RC. Kidney function in early diabetes: The tubular hypothesis of glomerular filtration. Am J Physiol Renal Physiol. 2004;286:8-15.
25. Montilla P, Barcos M, Munoz MC, Bujalance I, Munoz- Castaneda JR, Tunez I. Red wine prevents brain oxidative stress and nephropathy in streptozotocin-induced diabetic rats. J Biochem Mol Biol. 2005;38:539-544. (Pubitemid 43240987)
26. Chen H, Brahmbhatt S, Gupta A, Sharma AC. Duration of streptozotocin-induced diabetes differentially affects p 38- mitogen-activated protein kinase (MAPK) phosphorylation in renal and vascular dysfunction. Cardiovasc Diabetol. 2005;4:3.
27. Khan MAH, Sattar MA, Abdullah NA, et al. Functional subtypes of renal-adrenoceptor in spontaneously hypertensive rats with streptozotocin- induced experimental diabetic nephropathy. Kidney Blood Press Res. 2009;32:349-359.
28. Casey RG, Joyce M, Roche-Nagle G, Chen G, Bouchier- Hayes D. Pravastatin modulates early diabetic nephropathy in an experimental model of diabetic renal disease. J Surg Res. 2005;123:176-181. (Pubitemid 40186894)
29. Vallon V, Osswald H. Dipyridamole prevents diabetes-induced alterations of kidney function in rats. Naunyn Schmied Arch Pharmacol. 1994;349:217-222. (Pubitemid 24059769)
30. Hostetter TH. Hyperfiltration and glomerulosclerosis. Semin Nephrol. 2003;23:194-199. (Pubitemid 36397101)
31. Ruggenenti P, Schieppati A, Remuzzi G. Progression, remission, regression of chronic renal diseases. Lancet. 2001;357:1601-1608. (Pubitemid 32488830)
32. Arima S, Ito S. The mechanisms underlying altered vascular resistance of glomerular afferent and efferent arterioles in diabetic nephropathy. Nephrol Dial Transplant. 2003;18: 1966-1969. (Pubitemid 37220296)
33. Wolf G, Ziyadeh FN. The role of angiotensin II in diabetic nephropathy: Emphasis on nonhemodynamic mechanisms? 1. Am J Kidney Dis. 1997;29:153-163. (Pubitemid 27020811)
34. Vidotti DB, Casarini DE, Cristovam PC, Leite CA, Schor N, Boim MA. High glucose concentration stimulates intracellular renin activity and angiotensin II generation in rat mesangial cells. Am J Physiol Renal Physiol. 2004;286:F1039-F1045. (Pubitemid 38656357)
35. Singh R, Singh AK, Alavi N, Leehey DJ. Mechanism of increased angiotensin II levels in glomerular mesangial cells cultured in high glucose. J Am Soc Nephrol. 2003;14: 873-880. (Pubitemid 36359269)
36. Hsieh TJ, Zhang SL, Filep JG, Tang SS, Ingelfinger JR, Chan JSD. High glucose stimulates angiotensinogen gene expression via reactive oxygen species generation in rat kidney proximal tubular cells. Endocrinology. 2002;143:2975-2986.
37. Zhang SL, To C, Chen X, et al. Essential role (s) of the intrarenal renin-angiotensin system in transforming growth factor-1 gene expression and induction of hypertrophy of rat kidney proximal tubular cells in high glucose. J Am Soc Nephrol. 2002;13:302-312. (Pubitemid 34106271)
38. Alexander WD, Branch RA, Levine DF, Hartog M. The urinary sodium: Potassium ratio and response to diuretics in resistant oedema. Postgrad Med J. 1977;53:117-121. (Pubitemid 8057384)
39. Edmonds CJ, Wilson GM. The action of hydroflumethiazide in relation to adrenal steroids and potassium loss. Lancet. 1960;1:505-509.
40. Laggner H, Hermann M, Esterbauer H, et al. The novel gaseous vasorelaxant hydrogen sulfide inhibits angiotensinconverting enzyme activity of endothelial cells. J Hypertens. 2007;25:2100-2104. (Pubitemid 47476307)
41. Raij L. Workshop: Hypertension and cardiovascular risk factors. Role of the angiotensin II-nitric oxide interaction. Hypertension. 2001;37:767-773. (Pubitemid 32199064)
42. Li L, Moore PK. Putative biological roles of hydrogen sulfide in health and disease: A breath of not so fresh air? Trends Pharmacol Sci. 2008;29:84-90.
43. Wong WT,Wong SL, Tian XY, Huang Y. Endothelial dysfunction: The common consequence in diabetes and hypertension. J Cardiovasc Pharmacol. 2010;55:300-307.
44. Laight DW, Carrier MJ, Änggård EE. Antioxidants, diabetes and endothelial dysfunction. Cardiovasc Res. 2000; 47: 457-464. (Pubitemid 30646068)
45. Vlassara H, Fuh H, Makita Z, Krungkrai S, Cerami A, Bucala R. Exogenous advanced glycosylation end products induce complex vascular dysfunction in normal animals: A model for diabetic and aging complications. Proc Natl Acad Sci USA. 1992;89:12043-12047. (Pubitemid 23004781)
46. Hink U, Li H, Mollnau H, et al. Mechanisms underlying endothelial dysfunction in diabetes mellitus. Circ Res. 2001;88:e14-e22.
47. Shibuya N, Mikami Y, Kimura Y, Nagahara N, Kimura H. Vascular endothelium expresses 3-mercaptopyruvate sulfurtransferase and produces hydrogen sulfide. J Biochem. 2009;146:623-626.
48. Jain SK, Bull R, Rains JL, et al. Low levels of hydrogen sulfide in the blood of diabetes patients and streptozotocintreated rats causes vascular inflammation? Antioxid Redox Signal. 2010;12:1333-1337.
49. De Vriese AS, Verbeuren TJ, Van de Voorde J, Lameire NH, Vanhoutte PM. Endothelial dysfunction in diabetes. Br J Pharmacol. 2000;130:963-974. (Pubitemid 30453529)
50. Chunyu Z, Junbao D, Dingfang B, Hui Y, Xiuying T, Chaoshu T. The regulatory effect of hydrogen sulfide on hypoxic pulmonary hypertension in rats? 1. Biochem Biophys Res Commun. 2003;302:810-816.
51. Kimura Y, Kimura H. Hydrogen sulfide protects neurons from oxidative stress. FASEB J. 2004;18:1165-1167. (Pubitemid 39561558)
52. Hong-ling WEI, Zhang CY, Hong-fang JIN, Chao-Shu T, Jun-bao DU. Hydrogen sulfide regulates lung tissue-oxidized glutathione and total antioxidant capacity in hypoxic pulmonary hypertensive rats. Acta Pharmacol Sin. 2008;29: 670-676. (Pubitemid 351799470)