Stimulation of peripheral Kappa opioid receptors inhibits inflammatory hyperalgesia via activation of the PI3Kγ/AKT/nNOS/NO signaling pathway

Molecular Pain

Volumn 8, Issue , 2012, Pages

  Cunha, Thiago M ^a   Souza, Guilherme R ^a   Domingues, Andressa C ^a   Carreira, Eleonora U ^a   Lotufo, Celina M ^a,b   Funez, Mani I ^a,c   Verri Jr, Waldiceu A ^a,d   Cunha, Fernando Q ^a   Ferreira, Sergio H ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF UBERLÂNDIA   (Brazil)

^c UNIVERSITY OF BRASILIA   (Brazil)

^d STATE UNIVERSITY OF LONDRINA   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE; 5 (6 QUINOXALINYLMETHYLENE) 2,4 THIAZOLIDINEDIONE; KAPPA OPIATE RECEPTOR; N(G) METHYLARGININE; NEURONAL NITRIC OXIDE SYNTHASE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PROSTAGLANDIN E2; PROTEIN KINASE B; WORTMANNIN; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE;

ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DRUG ANTAGONISM; ENZYME ACTIVATION; HYPERALGESIA; IMMUNOFLUORESCENCE; INCUBATION TIME; MALE; MOUSE; NOCICEPTIVE RECEPTOR; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; TREATMENT RESPONSE; ANIMAL; C57BL MOUSE; DRUG EFFECT; DRUG POTENTIATION; ENZYMOLOGY; INFLAMMATION; METABOLISM; NOCICEPTION; PATHOLOGY; PERIPHERAL NERVOUS SYSTEM;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; ANIMALS; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; DINOPROSTONE; ENZYME ACTIVATION; HYPERALGESIA; INFLAMMATION; MALE; MICE; MICE, INBRED C57BL; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE I; NOCICEPTION; PERIPHERAL NERVOUS SYSTEM; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RECEPTORS, OPIOID, KAPPA; SIGNAL TRANSDUCTION;

EID: 84856612053     PISSN: None     EISSN: 17448069     Source Type: Journal    
DOI: 10.1186/1744-8069-8-10     Document Type: Article

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