Implications of phosphoinositide 3-kinase in the μ- and δ-opioid receptor-mediated supraspinal antinociception in the mouse

Neuroscience

Volumn 113, Issue 3, 2002, Pages 647-652

  Narita, M ^a   Ohnishi, O ^a   Nemoto, M ^a   Yajima, Y ^a   Suzuki, T ^a  

^a HOSHI UNIVERSITY   (Japan)

Author keywords

Antinociception; Mouse; Opioid; Phosphoinositide 3 kinase; Phospholipase C

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTOMORPHIN II[2 DEXTRO ALANINE]; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; MORPHINE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; UNCLASSIFIED DRUG; WORTMANNIN; NARCOTIC ANALGESIC AGENT;

ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DOSE RESPONSE; IMMUNOASSAY; IMMUNOBLOTTING; MALE; MEDULLA OBLONGATA; MOUSE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; ANIMAL; DRUG POTENTIATION; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; METABOLISM; PAIN; SIGNAL TRANSDUCTION; TIME; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANALGESICS, OPIOID; ANIMAL; BLOTTING, WESTERN; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; ENKEPHALIN, D-PENICILLAMINE (2,5)-; INJECTIONS, INTRAVENTRICULAR; MALE; MICE; PAIN; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T; TIME FACTORS; ANIMALS;

EID: 0037008883     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(02)00197-5     Document Type: Article

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