Activation of a Tip60/E2F1/ERCC1 network in human lung adenocarcinoma cells exposed to cisplatin

Carcinogenesis

Volumn 33, Issue 2, 2012, Pages 320-325

  Van Den Broeck, Arnaud ^a,b   Nissou, Damien ^a,b   Brambilla, Elisabeth ^a,b   Eymin, Beatrice ^a,b   Gazzeri, Sylvie ^a,b  

^a INSTITUT ALBERT BONNIOT   (France)

^b UNIV GRENOBLE ALPES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; PROTEIN P300; TIP60 PROTEIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CARCINOMA CELL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG ADENOCARCINOMA; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SITE DIRECTED MUTAGENESIS; TRANSLATION INITIATION;

EID: 84856582016     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgr292     Document Type: Article

References (34)

1. Kamine, J. et al. (1996) Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivator. Virology, 216, 357-366.
2. Kimura, A. et al. (1998) Tip60 acetylates six lysines of a specific class in core histones in vitro. Genes Cells, 3, 789-800.
3. Squatrito, M. et al. (2006) Tip60 in DNA damage response and growth control: many tricks in one HAT. Trends Cell Biol., 16, 433-442.
4. Charvet, C. et al. (2011) Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Mol. Cell, 42, 584-596.
5. Tang, Y. et al. (2006) Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol. Cell, 24, 827-839.
6. Sun, Y. et al. (2005) A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM. Proc. Natl Acad. Sci. U S A, 102, 13182-13187.
7. Lin, W.C. et al. (2001) Selective induction of E2F1 in response to DNA damage, mediated by ATM-dependent phosphorylation. Genes Dev., 15, 1833-1844.
8. Stevens, C. et al. (2003) Chk2 activates E2F-1 in response to DNA damage. Nat. Cell Biol., 5, 401-409.
9. Blattner, C. et al. (1999) Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53. Mol. Cell Biol., 19, 3704-3713.
10. Stevens, C. et al. (2004) The emerging role of E2F-1 in the DNA damage response and checkpoint control. DNA Repair (Amst), 3, 1071-1079.
11. Maser, R.S. et al. (2001) Mre11 complex and DNA replication: linkage to E2F and sites of DNA synthesis. Mol. Cell Biol., 21, 6006-6016.
12. Liu, K. et al. (2003) Regulation of E2F1 by BRCT domain-containing protein TopBP1. Mol. Cell Biol., 23, 3287-3304.
13. Guo, R. et al. (1930) E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair. J. Biol. Chem., 285, 8-15.
14. Guo, R. et al. (2011) GCN5 and E2F1 stimulate nucleotide excision repair by promoting H3K9 acetylation at sites of damage. Nucleic Acids Res., 39, 1390-1397.
15. Pediconi, N. et al. (2003) Differential regulation of E2F1 apoptotic target genes in response to DNA damage. Nat. Cell Biol., 5, 552-558.
16. Ianari, A. et al. (2004) Specific role for p300/CREB-binding protein-associated factor activity in E2F1 stabilization in response to DNA damage. J. Biol. Chem., 279, 30830-30835.
17. Salon, C. et al. (2007) E2F-1, Skp2 and cyclin E oncoproteins are upregulated and directly correlated in high-grade neuroendocrine lung tumors. Oncogene, 26, 6927-6936.
18. Leduc, C. et al. (2006) p14ARF promotes RB accumulation through inhibition of its Tip60-dependent acetylation. Oncogene, 25, 4147-4154.
19. Eymin, B. et al. (2001) Human ARF binds E2F1 and inhibits its transcriptional activity. Oncogene, 20, 1033-1041.
20. Van Den Broeck, A. et al. (2008) Loss of histone H4K20 trimethylation occurs in preneoplasia and influences prognosis of non-small cell lung cancer. Clin. Cancer Res., 14, 7237-7245.
21. Taubert, S. et al. (2004) E2F-dependent histone acetylation and recruitment of the Tip60 acetyltransferase complex to chromatin in late G1. Mol. Cell Biol., 24, 4546-4556.
22. Martinez-Balbas, M.A. et al. (2000) Regulation of E2F1 activity by acetylation. EMBO J., 19, 662-671.
23. Lemercier, C. et al. (2003) Tip60 acetyltransferase activity is controlled by phosphorylation. J. Biol. Chem., 278, 4713-4718.
24. Ikura, T. et al. (2000) Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosis. Cell, 102, 463-473.
25. Hofferer, M. et al. (1999) Increased levels of E2F-1-dependent DNA binding activity after UV- or gamma-irradiation. Nucleic Acids Res., 27, 491-495.
26. Marzio, G. et al. (2000) E2F family members are differentially regulated by reversible acetylation. J. Biol. Chem., 275, 10887-10892.
27. Zamble, D.B. et al. (1996) Repair of cisplatin-DNA adducts by the mammalian excision nuclease. Biochemistry, 35, 10004-10013.
28. Sancar, A. (1994) Mechanisms of DNA excision repair. Science, 266, 1954-1956.
29. Mu, D. et al. (1996) Reaction mechanism of human DNA repair excision nuclease. J. Biol. Chem., 271, 8285-8294.
30. Westerveld, A. et al. (1984) Molecular cloning of a human DNA repair gene. Nature, 310, 425-429.
31. Takenaka, T. et al. (2007) Combined evaluation of Rad51 and ERCC1 expressions for sensitivity to platinum agents in non-small cell lung cancer. Int. J. Cancer, 121, 895-900.
32. Olaussen, K.A. et al. (2006) DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N. Engl. J. Med., 355, 983-991.
33. Miyamoto, N. et al. (2008) Tip60 is regulated by circadian transcription factor clock and is involved in cisplatin resistance. J. Biol. Chem., 283, 18218-18226.
34. Hirano, G. et al. (2011) Enhanced expression of PCAF endows apoptosis resistance in cisplatin-resistant cells. Mol. Cancer Res., 8, 864-872.