The use of an artificial skin model to study transdermal absorption of drugs in inflamed skin

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 2, 2012, Pages 203-209

  Oshima, Shinji ^a   Suzuki, Chihiro ^a   Yajima, Rina ^a   Egawa, Yuya ^a   Hosoya, Osamu ^a   Juni, Kazuhiko ^a   Seki, Toshinobu ^a  

^a JOSAI UNIVERSITY   (Japan)

Author keywords

Flurbiprofen; Inflamed skin; Model skin system; Protein binding; Skin absorption

Indexed keywords

BOVINE SERUM ALBUMIN; CARRAGEENAN; CASEIN; FLURBIPROFEN; SILICONE; ZYMOSAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL SKIN; CONTROLLED STUDY; DIALYSIS MEMBRANE; DRUG ABSORPTION; DRUG CLEARANCE; FLOW RATE; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; SKIN INFLAMMATION; SKIN IRRITATION; STRATUM CORNEUM;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; DERMATITIS, IRRITANT; FLURBIPROFEN; IRRITANTS; MALE; MEMBRANES, ARTIFICIAL; MODELS, BIOLOGICAL; RATS; RATS, HAIRLESS; SILICONES; SKIN; SKIN ABSORPTION;

EID: 84856576785     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.35.203     Document Type: Article

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