A new in-situ experimental method to evaluate the cutaneous disposition of flurbiprofen after topical application in hairless rats

Pharmacy and Pharmacology Communications

Volumn 4, Issue 5, 1998, Pages 261-265

  Yanagimoto, G ^a   Hayashi, T ^a   Seki, T ^a   Juni, K ^a   Sugibayashi, K ^a   Morimoto, Y ^a  

^a JOSAI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AGAR; FLURBIPROFEN;

ANIMAL EXPERIMENT; ARTICLE; BOLUS INJECTION; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG FORMULATION; DRUG INFUSION; INTRAVENOUS DRUG ADMINISTRATION; MALE; METHODOLOGY; NONHUMAN; RAT; TOPICAL DRUG ADMINISTRATION;

EID: 0031745231     PISSN: 14608081     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

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2. Ault, J. M., Lunte, C. E., Meltzer, N. M., Riley, C. M. (1992) Microdialysis sampling for the investigation of dermal drug transport. Pharm. Res. 9: 1256-1261
3. Guy, R. H., Maibach, H. I. (1983) Drug delivery to local subcutaneous structures following topical administration. J. Pharm. Sci. 72: 1375-1380
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8. Singh, P., Roberts, M. S. (1994a) Skin permeability and local tissue concentrations of nonsteroidal anti-inflammatory drugs after topical application. J. Pharmacol. Exp. Ther. 268: 144-151
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