The effect of irritant dermatitis on cutaneous bioavailability of a metronidazole formulation, investigated by microdialysis and dermatopharmacokinetic method

Contact Dermatitis

Volumn 59, Issue 1, 2008, Pages 23-30

  García Ortiz, Patricia ^a,b   Hansen, Steen Honoré ^b   Shah, Vinod P ^c,d   Menné, Torkil ^a   Benfeldt, Eva ^a  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^d NONE

Author keywords

Irritant dermatitis; Metronidazole; Microdialysis; Tape strip sampling; Topical penetration

Indexed keywords

LIDOCAINE; METRONIDAZOLE;

ADULT; ARTICLE; CLINICAL ARTICLE; CREAM; DRUG BIOAVAILABILITY; DRUG PENETRATION; FEMALE; HUMAN; HUMAN EXPERIMENT; IRRITANT DERMATITIS; MALE; MICRODIALYSIS; NORMAL HUMAN;

ADMINISTRATION, CUTANEOUS; ADULT; ANALYSIS OF VARIANCE; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; DERMATITIS, IRRITANT; DERMATOLOGIC AGENTS; ERYTHEMA; FEMALE; HUMANS; LINEAR MODELS; MALE; METRONIDAZOLE; MICRODIALYSIS; MIDDLE AGED; SKIN; SKIN ABSORPTION; SODIUM DODECYL SULFATE; WATER LOSS, INSENSIBLE;

EID: 47249137391     PISSN: 01051873     EISSN: 16000536     Source Type: Journal    
DOI: 10.1111/j.1600-0536.2008.01348.x     Document Type: Article

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