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Volumn 27, Issue 4, 2012, Pages 1245-1250

Synergistic cytotoxic effect of sulindac and pyrrolidine dithiocarbamate against ovarian cancer cells

Author keywords

Apoptosis; Ovarian cancer; Pyrrolidine dithiocarbamate; Sulindac

Indexed keywords

PROSTAGLANDIN SYNTHASE; PYRROLIDINE DITHIOCARBAMATE; SULINDAC;

EID: 84856562693     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.1639     Document Type: Article
Times cited : (5)

References (40)
  • 2
    • 74249089783 scopus 로고    scopus 로고
    • Phase II study of gefitinib in combination with paclitaxel (P) and carboplatin (C) as second-line therapy for ovarian, tubal or peritoneal adenocarcinoma (1839IL/0074)
    • Pautier P, Joly F, Kerbrat P, Bougnoux P, Fumoleau P, Petit T, Rixe O, Ringeisen F, Tisseron Carrasco A and Lhomme C: Phase II study of gefitinib in combination with paclitaxel (P) and carboplatin (C) as second-line therapy for ovarian, tubal or peritoneal adenocarcinoma (1839IL/0074). Gynecol Oncol 116: 157-162, 2010.
    • (2010) Gynecol Oncol , vol.116 , pp. 157-162
    • Pautier, P.1    Joly, F.2    Kerbrat, P.3    Bougnoux, P.4    Fumoleau, P.5    Petit, T.6    Rixe, O.7    Ringeisen, F.8    Tisseron Carrasco, A.9    Lhomme, C.10
  • 3
    • 77953478466 scopus 로고    scopus 로고
    • Carboplatin/gemcitabine alternating with carboplatin/pegylated liposomal doxorubicin and carboplatin/cyclophosphamide in platinum-refractory/resistant paclitaxel-pretreated ovarian carcinoma
    • Pectasides D, Pectasides E, Papaxoinis G, Psyrri A, Pliarchopoulou K, Koumarianou A, Macheras A, Athanasas G, Xiros N and Economopoulos T: Carboplatin/gemcitabine alternating with carboplatin/pegylated liposomal doxorubicin and carboplatin/cyclophosphamide in platinum-refractory/resistant paclitaxel-pretreated ovarian carcinoma. Gynecol Oncol 118: 52-57, 2010.
    • (2010) Gynecol Oncol , vol.118 , pp. 52-57
    • Pectasides, D.1    Pectasides, E.2    Papaxoinis, G.3    Psyrri, A.4    Pliarchopoulou, K.5    Koumarianou, A.6    Macheras, A.7    Athanasas, G.8    Xiros, N.9    Economopoulos, T.10
  • 4
    • 77956648238 scopus 로고    scopus 로고
    • Targeted trials in ovarian cancer
    • Ledermann JA and Raja FA: Targeted trials in ovarian cancer. Gynecol Oncol 119: 151-156, 2010.
    • (2010) Gynecol Oncol , vol.119 , pp. 151-156
    • Ledermann, J.A.1    Raja, F.A.2
  • 7
    • 55549143635 scopus 로고    scopus 로고
    • Concomitant DFMO and sulindac chemoprevention of colorectal adenomas: A major clinical advance
    • Sporn MB and Hong WK: Concomitant DFMO and sulindac chemoprevention of colorectal adenomas: a major clinical advance. Nat Clin Pract Oncol 5: 628-629, 2008.
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 628-629
    • Sporn, M.B.1    Hong, W.K.2
  • 8
    • 0032889225 scopus 로고    scopus 로고
    • Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits
    • DOI 10.1038/sj.bjc.6690020
    • Verheul HMW, Panigrahy D, Yuan J and D'Amato RJ: Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits. Br J Cancer 79: 114-118, 1999. (Pubitemid 28566935)
    • (1999) British Journal of Cancer , vol.79 , Issue.1 , pp. 114-118
    • Verheul, H.M.W.1    Panigrahy, D.2    Yuan, J.3    D'Amato, R.J.4
  • 10
    • 0036154835 scopus 로고    scopus 로고
    • Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: Preclinical evaluation of NSAIDs as chemopreventive agents
    • Rodriguez-Burford C, Barnes MN, Oelschlager DK, Myers RB, Talley LI, Partridge EE and Grizzle WE: Effects of non-steroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents. Clin Cancer Res 8: 202-209, 2002. (Pubitemid 34101479)
    • (2002) Clinical Cancer Research , vol.8 , Issue.1 , pp. 202-209
    • Rodriguez-Burford, C.1    Barnes, M.N.2    Oelschlager, D.K.3    Myers, R.B.4    Talley, L.I.5    Partridge, E.E.6    Grizzle, W.E.7
  • 11
    • 0037374468 scopus 로고    scopus 로고
    • Cyclooxygenase-1 is overexpressed and promotes angiogenic growth factor production in ovarian cancer
    • Gupta RA, Tejada LV, Tong BJ, Das SK, Morrow JD, Dey SK and DuBois RN: Cyclooxygenase-1 is overexpressed and promotes angiogenic factor production in ovarian cancer. Cancer Res 63: 906-911, 2003. (Pubitemid 36278417)
    • (2003) Cancer Research , vol.63 , Issue.5 , pp. 906-911
    • Gupta, R.A.1    Tejada, L.V.2    Tong, B.J.3    Das, S.K.4    Morrow, J.D.5    Dey, S.K.6    DuBois, R.N.7
  • 13
    • 36349003399 scopus 로고    scopus 로고
    • A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro
    • DOI 10.1007/s00280-007-0462-3
    • Andrews P, Zhao X, Allen J, Li F and Chang M: A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro. Cancer Chemother Pharmacol 61: 203-214, 2008. (Pubitemid 350160319)
    • (2008) Cancer Chemotherapy and Pharmacology , vol.61 , Issue.2 , pp. 203-214
    • Andrews, P.1    Zhao, X.2    Allen, J.3    Li, F.4    Chang, M.5
  • 15
    • 51049124324 scopus 로고    scopus 로고
    • Antiproliferative effect of sulindac in colonic neoplasia prevention: Role of COOH-terminal Src kinase
    • Kunte DP, Wali RK, Koetsier JL and Roy HK: Antiproliferative effect of sulindac in colonic neoplasia prevention: role of COOH-terminal Src kinase. Mol Cancer Ther 7: 1797-1806, 2008.
    • (2008) Mol Cancer Ther , vol.7 , pp. 1797-1806
    • Kunte, D.P.1    Wali, R.K.2    Koetsier, J.L.3    Roy, H.K.4
  • 16
    • 33747125836 scopus 로고    scopus 로고
    • Differential targeting of protein kinase B in cell death induced by sulindac and its metabolite sulindac sulfide
    • Marotta A, Parhar K, Hundal R, Duronio V and Salh B: Differential targeting of protein kinase B in cell death induced by sulindac and its metabolite sulindac sulfide. Int J Oncol 28: 1471-1479, 2006.
    • (2006) Int J Oncol , vol.28 , pp. 1471-1479
    • Marotta, A.1    Parhar, K.2    Hundal, R.3    Duronio, V.4    Salh, B.5
  • 17
    • 33845627233 scopus 로고    scopus 로고
    • Sulindac induces specific degradation of the HPV oncoprotein E7 and causes growth arrest and apoptosis in cervical carcinoma cells
    • DOI 10.1016/j.canlet.2005.12.034, PII S0304383506000048
    • Karl T, Seibert N, Stohr M, Osswald H, Rosl F and Finzer P: Sulindac induces specific degradation of the HPV oncoprotein E7 and causes growth arrest and apoptosis in cervical carcinoma cells. Cancer Lett 245: 103-111, 2007. (Pubitemid 44959344)
    • (2007) Cancer Letters , vol.245 , Issue.1-2 , pp. 103-111
    • Karl, T.1    Seibert, N.2    Stohr, M.3    Osswald, H.4    Rosl, F.5    Finzer, P.6
  • 18
    • 33847363510 scopus 로고    scopus 로고
    • JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo
    • DOI 10.1016/j.ejphar.2007.01.020, PII S0014299907000374
    • Song Z, Tong C, Liang J, Dockendorff A, Huang C, Augenlicht LH and Yang W: JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo. Eur J Pharmacol 560: 95-100, 2007. (Pubitemid 46341306)
    • (2007) European Journal of Pharmacology , vol.560 , Issue.2-3 , pp. 95-100
    • Song, Z.1    Tong, C.2    Liang, J.3    Dockendorff, A.4    Huang, C.5    Augenlicht, L.H.6    Yang, W.7
  • 19
    • 15944422900 scopus 로고    scopus 로고
    • The conventional nonsteroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15
    • Kim JS, Baek SJ, Sali T and Eling TE: The conventional non-steroidal anti-inflammatory drug sulindac sulfide arrests ovarian cancer cell growth via the expression of NAG-1/MIC-1/GDF-15. Mol Cancer Ther 4: 487-493, 2005. (Pubitemid 40443934)
    • (2005) Molecular Cancer Therapeutics , vol.4 , Issue.3 , pp. 487-493
    • Kim, J.-S.1    Baek, S.J.2    Sali, T.3    Eling, T.E.4
  • 20
    • 0037139924 scopus 로고    scopus 로고
    • PPARγ-mediated antineoplastic effect of NSAID sulindac on human oral squamous carcinoma cells
    • DOI 10.1002/ijc.10278
    • Nikitakis NG, Hebert C, Lopes MA, Reynolds MA and Sauk JJ: PPARγ-mediated antineoplastic effect of NSAID sulindac on human oral squamous carcinoma cells. Int J Cancer 98: 817-823, 2002. (Pubitemid 34286675)
    • (2002) International Journal of Cancer , vol.98 , Issue.6 , pp. 817-823
    • Nikitakis, N.G.1    Hebert, C.2    Lopes, M.A.3    Reynolds, M.A.4    Sauk, J.J.5
  • 21
    • 48749127647 scopus 로고    scopus 로고
    • Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases
    • Park JH, Kim EJ, Jang HY, Shim H, Lee KK, Jo HJ, Kim HJ, Yang SH, Jeong ET and Kim HR: Combination treatment with arsenic trioxide and sulindac enhances apoptotic cell death in lung cancer cells via activation of oxidative stress and mitogen-activated protein kinases. Oncol Rep 20: 379-384, 2008.
    • (2008) Oncol Rep , vol.20 , pp. 379-384
    • Park, J.H.1    Kim, E.J.2    Jang, H.Y.3    Shim, H.4    Lee, K.K.5    Jo, H.J.6    Kim, H.J.7    Yang, S.H.8    Jeong, E.T.9    Kim, H.R.10
  • 22
    • 61449117031 scopus 로고    scopus 로고
    • Inhibitory effects of 5-fluorouracil and oxaliplatin on human colorectal cancer cell survival are synergistically enhanced by sulindac sulfide
    • Flis S and Spławiński J: Inhibitory effects of 5-fluorouracil and oxaliplatin on human colorectal cancer cell survival are synergistically enhanced by sulindac sulfide. Anticancer Res 29: 435-442, 2009.
    • (2009) Anticancer Res , vol.29 , pp. 435-442
    • Flis, S.1    Spławiński, J.2
  • 23
    • 33846398570 scopus 로고    scopus 로고
    • Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells
    • DOI 10.1016/j.ygyno.2006.08.008, PII S0090825806006159
    • Barnes AP, Miller BE and Kucera GL: Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells. Gynecol Oncol 104: 443-450, 2007. (Pubitemid 46135645)
    • (2007) Gynecologic Oncology , vol.104 , Issue.2 , pp. 443-450
    • Barnes, A.P.1    Miller, B.E.2    Kucera, G.L.3
  • 24
    • 65649128221 scopus 로고    scopus 로고
    • A phase II study of carboplatin, etoposide, and exisulind in patients with extensive small cell lung cancer: CALGB 3014
    • Cancer and Leukemia Group B
    • Govindan R, Wang X, Baggstrom MQ, Burdette-Radoux S, Hodgson L, Vokes EE, Green MR and Cancer and Leukemia Group B: A phase II study of carboplatin, etoposide, and exisulind in patients with extensive small cell lung cancer: CALGB 3014. J Thorac Oncol 4: 220-226, 2009.
    • (2009) J Thorac Oncol , vol.4 , pp. 220-226
    • Govindan, R.1    Wang, X.2    Baggstrom, M.Q.3    Burdette-Radoux, S.4    Hodgson, L.5    Vokes, E.E.6    Green, M.R.7
  • 26
    • 78049278346 scopus 로고    scopus 로고
    • Fetal bovine serum requirement for pyrrolidine dithiocarbamate-induced apoptotic cell death of MCF-7 breast tumor cells
    • Oh DH, Bang JS, Choi HM, Yang HI, Yoo MC and Kim KS: Fetal bovine serum requirement for pyrrolidine dithiocarbamate-induced apoptotic cell death of MCF-7 breast tumor cells. Eur J Pharmacol 649: 135-139, 2010.
    • (2010) Eur J Pharmacol , vol.649 , pp. 135-139
    • Oh, D.H.1    Bang, J.S.2    Choi, H.M.3    Yang, H.I.4    Yoo, M.C.5    Kim, K.S.6
  • 27
    • 21344440550 scopus 로고    scopus 로고
    • Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis
    • Chen D, Peng F, Cui QC, Danie KG, Orlu S, Liu J and Dou QP: Inhibition of prostate cancer cellular proteasome activity by a pyrrolidine dithiocarbamate-copper complex is associated with suppression of proliferation and induction of apoptosis. Front Biosc 10: 2932-2939, 2005. (Pubitemid 40910532)
    • (2005) Frontiers in Bioscience , vol.10 , Issue.SUPPL. 3 , pp. 2932-2939
    • Chen, D.1    Peng, F.2    Cui, Q.C.3    Daniel, K.G.4    Orlu, S.5    Liu, J.6    Dou, Q.P.7
  • 28
    • 0030663670 scopus 로고    scopus 로고
    • Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: A p53-independent induction of p21(WAF1/CIP1) via C/EBPβ
    • Chinery R, Brockman JA, Peeler MO, Shyr Y, Beauchamp RD and Coffey RJ: Antioxidants enhance the cytotoxicity of chemotherapeutic agents in colorectal cancer: a p53-independent induction of p21WAF1/CIP1 via C/EBPβ. Nat Med 3: 1233-1241, 1997. (Pubitemid 27508824)
    • (1997) Nature Medicine , vol.3 , Issue.11 , pp. 1233-1241
    • Chinery, R.1    Brockman, J.A.2    Peeler, M.O.3    Shyr, Y.4    Beauchamp, R.D.5    Coffey, R.J.6
  • 29
    • 77951667799 scopus 로고    scopus 로고
    • Inhibition of nuclear factor kappa B transcription activity drives a synergistic effect of pyrrolidine dithiocarbamate and cisplatin for treatment of renal cell carcinoma
    • Morais C, Gobe G, Johnson DW and Healy H: Inhibition of nuclear factor kappa B transcription activity drives a synergistic effect of pyrrolidine dithiocarbamate and cisplatin for treatment of renal cell carcinoma. Apoptosis 14: 412-425, 2010.
    • (2010) Apoptosis , vol.14 , pp. 412-425
    • Morais, C.1    Gobe, G.2    Johnson, D.W.3    Healy, H.4
  • 30
    • 33749143836 scopus 로고    scopus 로고
    • Inhibition of nuclear factor-κB by an antioxidant enhances paclitaxel sensitivity in ovarian carcinoma cell line
    • DOI 10.1111/j.1525-1438.2006.00652.x
    • Liu GH, Wang SR, Wang B and Kong BH: Inhibition of nuclear factor-κB by an antioxidant enhances paclitaxel sensitivity in ovarian carcinoma cell line. Int J Gynecol Cancer 16: 1777-1782, 2006. (Pubitemid 44470035)
    • (2006) International Journal of Gynecological Cancer , vol.16 , Issue.5 , pp. 1777-1782
    • Liu, G.H.1    Wang, S.R.2    Wang, B.3    Kong, B.H.4
  • 31
    • 66149153421 scopus 로고    scopus 로고
    • Oral administration of pyrrolidine dithiocarbamate (PDTC) inhibits VEGF expression, tumor angiogenesis and growth of breast cancer in female mice
    • Gu JW, Young E, Busby B, Covington J, Tan W and Johnson JW: Oral administration of pyrrolidine dithiocarbamate (PDTC) inhibits VEGF expression, tumor angiogenesis and growth of breast cancer in female mice. Cancer Biol Ther 8: 514-521, 2009.
    • (2009) Cancer Biol Ther , vol.8 , pp. 514-521
    • Gu, J.W.1    Young, E.2    Busby, B.3    Covington, J.4    Tan, W.5    Johnson, J.W.6
  • 32
    • 79955422412 scopus 로고    scopus 로고
    • Antitumor effects of sulindac in ovarian cancer cell cultures
    • In Polish
    • Jakubowska-Mucka A, Sienko J, Switaj T, Golab J and Lasek W: Antitumor effects of sulindac in ovarian cancer cell cultures. Ginekol Pol 82: 195-199, 2011 (In Polish).
    • (2011) Ginekol Pol , vol.82 , pp. 195-199
    • Jakubowska-Mucka, A.1    Sienko, J.2    Switaj, T.3    Golab, J.4    Lasek, W.5
  • 33
    • 0021118703 scopus 로고
    • Quantitive analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou TC and Talalay P: Quantitive analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv Enzyme Regul 22: 27-55, 1984.
    • (1984) Adv Enzyme Regul , vol.22 , pp. 27-55
    • Chou, T.C.1    Talalay, P.2
  • 34
    • 67649586668 scopus 로고    scopus 로고
    • Sulindac induces apoptotic cell death in susceptible human breast cancer cells through, at least in part, inhibition of IKKβ
    • Seo AM, Hong SW, Shin JS, Park IC, Hong NJ, Kim DJ, Lee WK, Lee WJ, Jin DH and Lee MS: Sulindac induces apoptotic cell death in susceptible human breast cancer cells through, at least in part, inhibition of IKKβ. Apoptosis 14: 913-922, 2009.
    • (2009) Apoptosis , vol.14 , pp. 913-922
    • Seo, A.M.1    Hong, S.W.2    Shin, J.S.3    Park, I.C.4    Hong, N.J.5    Kim, D.J.6    Lee, W.K.7    Lee, W.J.8    Jin, D.H.9    Lee, M.S.10
  • 35
    • 0033578879 scopus 로고    scopus 로고
    • Sulindac inhibition activation of the NF-κB pathway
    • Yamamoto Y, Yin MJ, Lin KM and Gaynor RB: Sulindac inhibition activation of the NF-κB pathway. J Biol Chem 274: 27307-27314, 1999.
    • (1999) J Biol Chem , vol.274 , pp. 27307-27314
    • Yamamoto, Y.1    Yin, M.J.2    Lin, K.M.3    Gaynor, R.B.4
  • 36
    • 16844366650 scopus 로고    scopus 로고
    • Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
    • DOI 10.1038/nrc1588
    • Nakanishi C and Toi M: Nuclear factor κB inhibitors as sensitizers to anticancer drugs. Nature Rev Cancer 5: 297-309, 2005. (Pubitemid 40488635)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.4 , pp. 297-309
    • Nakanishi, C.1    Toi, M.2
  • 37
  • 39
    • 0032953411 scopus 로고    scopus 로고
    • Effect of taxol and taxotere on gene expression in macrophages: Induction of the prostaglandin H synthase-2 isoenzyme
    • Moos PJ, Muskardin DT and Fitzpatrick FA: Effect of taxol and taxotere on gene expression in macrophages: induction of the prostaglandin H synthase-2 isoenzyme. J Immunol 162: 467-473, 1999. (Pubitemid 29018955)
    • (1999) Journal of Immunology , vol.162 , Issue.1 , pp. 467-473
    • Moos, P.J.1    Muskardin, D.T.2    Fitzpatrick, F.A.3
  • 40
    • 71249149845 scopus 로고    scopus 로고
    • Anti-angiogenic actions of pyrrolidine dithiocarbamate, a nuclear factor kappa B inhibitor
    • Morais C, Gobe G, Johnson DW and Healy H: Anti-angiogenic actions of pyrrolidine dithiocarbamate, a nuclear factor kappa B inhibitor. Angiogenesis 12: 365-379, 2009.
    • (2009) Angiogenesis , vol.12 , pp. 365-379
    • Morais, C.1    Gobe, G.2    Johnson, D.W.3    Healy, H.4


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