Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain

Anesthesiology

Volumn 116, Issue 2, 2012, Pages 372-384

  Brambrink, Ansgar M ^a   Evers, Alex S ^a   Avidan, Michael S ^a   Farber, Nuri B ^b   Smith, Derek J ^b   Martin, Lauren D ^c   Dissen, Gregory A ^d   Creeley, Catherine E ^b   Olney, John W ^c  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; GLUCOSE; HEMOGLOBIN; KETAMINE; LACTIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN; BRAIN DEVELOPMENT; BRAIN NERVE CELL; CARBON DIOXIDE TENSION; ENZYME ACTIVATION; FEMALE; FETUS; HEART RATE; HEMOGLOBIN BLOOD LEVEL; MACACA; MEAN ARTERIAL PRESSURE; NERVE DEGENERATION; NEUROTOXICITY; NEWBORN; NONHUMAN; PERINATAL PERIOD; PH; PRIORITY JOURNAL; VENOUS OXYGEN TENSION;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BRAIN; FEMALE; FETUS; INFUSIONS, INTRAVENOUS; KETAMINE; MACACA MULATTA; NERVE DEGENERATION; PREGNANCY; RANDOM ALLOCATION;

EID: 84856506100     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e318242b2cd     Document Type: Article

References (47)

1. Ikonomidou C, Bosch F, Miksa M, Bittigau P, Vöckler J, Dikranian K, Tenkova TI, Stefovska V, Turski L, Olney JW: Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain. Science 1999; 283:70-4 (Pubitemid 29044848)
2. Ikonomidou C, Bittigau P, Ishimaru MJ, Wozniak DF, Koch C, Genz K, Price MT, Stefovska V, Hörster F, Tenkova T, Dikranian K, Olney JW: Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome. Science 2000; 287: 1056-60 (Pubitemid 30094364)
3. Olney JW, Tenkova T, Dikranian K, Qin YQ, Labruyere J, Ikonomidou C: Ethanol-induced apoptotic neurodegeneration in the developing C57BL/6 mouse brain. Brain Res Dev Brain Res 2002; 133:115-26 (Pubitemid 34211997)
4. Bittigau P, Sifringer M, Genz K, Reith E, Pospischil D, Govindarajalu S, Dzietko M, Pesditschek S, Mai I, Dikranian K, Olney JW, Ikonomidou C: Antiepileptic drugs and apoptotic neurodegeneration in the developing brain. Proc Natl Acad Sci USA 2002; 99:15089-94 (Pubitemid 35334614)
5. Jevtovic-Todorovic V, Hartman RE, Izumi Y, Benshoff ND, Dikranian K, Zorumski CF, Olney JW, Wozniak DF: Early exposure to common anesthetic agents causes widespread neurodegeneration in the developing rat brain and persistent learning deficits. J Neurosci 2003; 23:876-82 (Pubitemid 36206178)
6. Dobbing J, Sands J: Comparative aspects of the brain growth spurt. Early Hum Dev 1979; 3:79-83 (Pubitemid 9141710)
7. Dikranian K, Ishimaru MJ, Tenkova T, Labruyere J, Qin YQ, Ikonomidou C, Olney JW: Apoptosis in the in vivo mammalian forebrain. Neurobiol Dis 2001; 8:359-79 (Pubitemid 32566129)
8. Dikranian K, Qin YQ, Labruyere J, Nemmers B, Olney JW: Ethanol-induced neuroapoptosis in the developing rodent cerebellum and related brain stem structurE.S. Brain Res Dev Brain Res 2005; 155:1-13 (Pubitemid 40342947)
9. Olney JW, Tenkova T, Dikranian K, Muglia LJ, Jermakowicz WJ, D'Sa C, Roth KA: Ethanol-induced caspase-3 activation in the in vivo developing mouse brain. Neurobiol Dis 2002; 9:205-19 (Pubitemid 34261215)
10. Young C, Klocke BJ, Tenkova T, Choi J, Labruyere J, Qin YQ, Holtzman DM, Roth KA, Olney JW: Ethanol-induced neuronal apoptosis in vivo requires BAX in the developing mouse brain. Cell Death Differ 2003; 10:1148-55 (Pubitemid 37258580)
11. Young C, Roth KA, Klocke BJ, West T, Holtzman DM, Labruyere J, Qin YQ, Dikranian K, Olney JW: Role of caspase-3 in ethanol-induced developmental neurodegeneration. Neurobiol Dis 2005; 20:608-14 (Pubitemid 41476286)
12. Tenkova T, Young C, Dikranian K, Labruyere J, Olney JW: Ethanol-induced apoptosis in the developing visual system during synaptogenesis. Invest Ophthalmol Vis Sci 2003; 44: 2809-17 (Pubitemid 36759739)
13. Young C, Jevtovic-Todorovic V, Qin YQ, Tenkova T, Wang H, Labruyere J, Olney JW: Potential of ketamine and midazolam, individually or in combination, to induce apoptotic neurodegeneration in the infant mouse brain. Br J Pharmacol 2005; 146:189-97 (Pubitemid 43079958)
14. Cattano D, Young C, Straiko MM, Olney JW: Subanesthetic doses of propofol induce neuroapoptosis in the infant mouse brain. Anesth Analg 2008; 106:1712-4
15. Ma D, Williamson P, Januszewski A, Nogaro MC, Hossain M, Ong LP, Shu Y, Franks NP, Maze M: Xenon mitigates isoflurane-induced neuronal apoptosis in the developing rodent brain. Anesthesiology 2007; 106:746-53 (Pubitemid 46555618)
16. Johnson SA, Young C, Olney JW: Isoflurane-induced neuroapoptosis in the developing brain of non-hypoglycemic mice. J Neurosurg Anesth 2008; 20:21-8 (Pubitemid 351628035)
17. Zhang X, Xue Z, Sun A: Subclinical concentration of sevoflurane potentiates neuronal apoptosis in the developing C57BL/6 mouse brain. Neurosci Lett 2008; 447:109-14
18. Cattano D, Straiko MMW, Olney JW: Chloral hydrate induces and lithium prevents neuroapoptosis in the infant mouse brain. Presented at the Annual Meeting of American Society of Anesthesiologists, October 17, 2008, Orlando, Florida, #A315
19. Wozniak DF, Hartman RE, Boyle MP, Vogt SK, Brooks AR, Tenkova T, Young C, Olney JW, Muglia LJ: Apoptotic neurodegeneration induced by ethanol in neonatal mice is associated with profound learning/memory deficits in juveniles followed by progressive functional recovery in adults. Neurobiol Dis 2004; 17:403-14 (Pubitemid 39574874)
20. Slikker W Jr, Zou X, Hotchkiss CE, Divine RL, Sadovova N, Twaddle NC, Doerge DR, Scallet AC, Patterson TA, Hanig JP, Paule MG, Wang C: Ketamine-induced neuronal cell death in the perinatal rhesus monkey. Toxicol Sci 2007; 98:145-58 (Pubitemid 47073827)
21. Zou X, Patterson TA, Divine RL, Sadovova N, Zhang X, Hanig JP, Paule MG, Slikker W Jr, Wang C: Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain. Int J Dev Neurosci 2009; 27:727-31
22. Straiko MMW, Young C, Cattano D, Creeley CE, Wang H, Smith DJ, Johnson SA, Li ES, Olney JW: Lithium protects against anesthesia-induced developmental neuroapoptosis. Anesthesiology 2009; 110:662-8
23. Sanders RD, Xu J, Shu Y, Fidalgo A, Ma D, Maze M: General anesthetics induce apoptotic neurodegeneration in the neonatal rat spinal cord. Anesth Analg 2008; 106:1708-11
24. Zhong J, Yang X, Yao W, Lee W: Lithium protects ethanolinduced neuronal apoptosis. Biochem Biophys Res Commun 2006; 350:905-10 (Pubitemid 44596222)
25. Young C, Straiko MM, Johnson SA, Creeley C, Olney JW: Ethanol causes and lithium prevents neuroapoptosis and suppression of pERK in the infant mouse brain. Neurobiol Dis 2008; 31:355-60
26. Satomoto M, Satoh Y, Terui K, Miyao H, Takishima K, Ito M, Imaki J: Neonatal exposure to sevoflurane induces abnormal social behaviors and deficits in fear conditioning in mice. Anesthesiology 2009; 110:628-37
27. Brambrink AM, Evers AS, Avidan MS, Farber NB, Smith DJ, Zhang X, Dissen GA, Creeley CE, Olney JW: Isoflurane-induced neuroapoptosis in the neonatal rhesus macaque brain. Anesthesiology 2010; 112:834-41
28. Su PH, Chang YZ, Chen JY: Infant with in utero ketamine exposure: Quantitative measurement of residual dosage in hair. Pediatr Neonatol 2010; 51:279-84
29. Albright BB, Rayburn WF: Substance abuse among reproductive age women. Obstet Gynecol Clin North Am 2009; 36: 891-906
30. Moore DG, Turner JD, Parrott AC, Goodwin JE, Fulton SE, Min MO, Fox HC, Braddick FM, Axelsson EL, Lynch S, Ribeiro H, Frostick CJ, Singer LT: During pregnancy, recreational drug-using women stop taking ecstasy (3,4-methylenedioxy-N-methylamphetamine) and reduce alcohol consumption, but continue to smoke tobacco and cannabis: Initial findings from the Development and Infancy Study. J Psychopharmacol 2010; 24:1403-10
31. Fredriksson A, Pontén E, Gordh T, Eriksson P: Neonatal exposure to a combination of N-methyl-D-aspartate and gamma-aminobutyric acid type A receptor anesthetic agents potentiates apoptotic neurodegeneration and persistent behavioral deficits. Anesthesiology 2007; 107:427-36 (Pubitemid 47329541)
32. Fredriksson A, Archer T, Alm H, Gordh T, Eriksson P: Neurofunctional deficits and potentiated apoptosis by neonatal NMDA antagonist administration. Behav Brain Res 2004; 153: 367-76 (Pubitemid 38953110)
33. Fredriksson A, Archer T: Neurobehavioural deficits associated with apoptotic neurodegeneration and vulnerability for ADHD. Neurotox Res 2004; 6:435-56
34. Stratmann G, Sall JW, May LD, Bell JS, Magnusson KR, Rau V, Visrodia KH, Alvi RS, Ku B, Lee MT, Dai R: Isoflurane differentially affects neurogenesis and long-term neurocognitive function in 60-day-old and 7-day-old rats. Anesthesiology 2009; 110:834-48
35. DiMaggio C, Sun LS, Kakavouli A, Byrne MW, Li G: A retrospective cohort study of the association of anesthesia and hernia repair surgery with behavioral and developmental disorders in young children. J Neurosurg Anesthesiol 2009; 21:286-91
36. DiMaggio C, Sun LS, Li G: Early childhood exposure to anesthesia and risk of developmental and behavioral disorders in a birth cohort of 5824 twin pairs. Presented at The IARS and SAFEKIDS International Science Symposium, International Anesthesiology Research Society 2010 Annual Meeting, March 20, 2010, Honolulu, Hawaii, #ISS-A1
37. Kalkman CJ, Peelen L, Moons KG, Veenhuizen M, Bruens M, Sinnema G, de Jong TP: Behavior and development in children and age at the time of first anesthetic exposure. Anesthesiology 2009; 110:805-12
38. Thomas JJ, Choi JW, Bayman EO, Kimble KK, Todd MM, Block RI: Does anesthesia exposure in infancy affect academic performance in childhood? Presented at The IARS and SAFEKIDS International Science Symposium, International Anesthesiology Research Society 2010 Annual Meeting, March 20, 2010, Honolulu, Hawaii, #ISS-A4
39. Wilder RT, Flick RP, Sprung J, Katusic SK, Barbaresi WJ, Mickelson C, Gleich SJ, Schroeder DR, Weaver AL, Warner DO: Early exposure to anesthesia and learning disabilities in a population-based birth cohort. Anesthesiology 2009; 110: 796-804
40. Paule MG, Li M, Allen RR, Liu F, Zou X, Hotchkiss C, Hanig JP, Patterson TA, Slikker W Jr, Wang C: Ketamine anesthesia during the first week of life can cause long-lasting cognitive deficits in rhesus monkeys. Neurotoxicol Teratol 2011; 33: 220-30
41. Williams GD, Maan H, Ramamoorthy C, Kamra K, Bratton SL, Bair E, Kuan CC, Hammer GB, Feinstein JA: Perioperative complications in children with pulmonary hypertension undergoing general anesthesia with ketamine. Paediatr Anaesth 2010; 20:28-37
42. Hall RW, Shbarou RM: Drugs of choice for sedation and analgesia in the neonatal ICU. Clin Perinatol 2009; 36:15-26
43. Joselyn AS, Cherian VT, Joel S: Ketamine for labour analgesia. Int J Obstet Anesth 2010; 19:122-3
44. Farber NB, Creeley CE, Olney JW: Alcohol-induced neuroapoptosis in the fetal macaque brain. Neurobiol Dis 2010; 40:200-6
45. Mattson SN, Riley EP, Sowell ER, Jernigan TL, Sobel DF, Jones KL: A decrease in the size of the basal ganglia in children with fetal alcohol syndrome. Alcohol Clin Exp Res 1996; 20:1088-93 (Pubitemid 26314836)
46. Riley EP, McGee CL: Fetal alcohol spectrum disorders: An overview with emphasis on changes in brain and behavior. Exp Biol Med 2005; 230:357-65 (Pubitemid 40827700)
47. Ikonomidou C, Scheer I, Wilhelm T, Juengling FD, Titze K, Stöver B, Lehmkuhl U, Koch S, Kassubek J: Brain morphology alterations in the basal ganglia and the hypothalamus following prenatal exposure to antiepileptic drugs. Eur J Paediatr Neurol 2007; 11:297-301 (Pubitemid 47194447)