Effect of inspired CO 2 on the ventilatory response to high intensity exercise

Respiratory Physiology and Neurobiology

Volumn 180, Issue 2-3, 2012, Pages 283-288

  Fan, Jui Lin ^a   Leiggener, Christian ^a   Rey, Florian ^a   Kayser, Bengt ^a  

^a UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

CO 2; Exercise; Ventilatory control

Indexed keywords

CARBON DIOXIDE;

ADULT; ARTICLE; BREATHING; CARBON DIOXIDE BREATHING; EXERCISE; GAS EXCHANGE; HIGH INTENSITY EXERCISE; HUMAN; HUMAN EXPERIMENT; INSPIRATORY CAPACITY; LUNG VENTILATION; MALE; NORMAL HUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT PARAMETERS; TIDAL VOLUME;

ADMINISTRATION, INHALATION; ADULT; ANAEROBIC THRESHOLD; BICYCLING; CARBON DIOXIDE; DATA INTERPRETATION, STATISTICAL; EXERCISE; EXERCISE TEST; HEART RATE; HUMANS; HYPOCAPNIA; MALE; OXYGEN CONSUMPTION; PERCEPTION; PHYSICAL EXERTION; PULMONARY GAS EXCHANGE; PULMONARY VENTILATION; TIDAL VOLUME; YOUNG ADULT;

EID: 84856480499     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2011.12.004     Document Type: Article

References (44)

1. 2. Respir. Physiol. 1997, 109:15-28.
2. 2. J. Appl. Physiol. 1997, 82:746-754.
3. Babb T.G., Wood H.E., Mitchell G.S. Short- and long-term modulation of the exercise ventilatory response. Med. Sci. Sports Exerc. 2010, 42:1681-1687.
4. Beaver W.L., Wasserman K., Whipp B.J. A new method for detecting anaerobic threshold by gas exchange. J. Appl. Physiol. 1986, 60:2020-2027.
5. Bisgard G.E., Forster H.V., Mesina J., Sarazin R.G. Role of the carotid body in hyperpnea of moderate exercise in goats. J. Appl. Physiol. 1982, 52:1216-1222.
6. Borg G.A. Psychophysical bases of perceived exertion. Med. Sci. Sports Exerc. 1982, 14:377-381.
7. Clark J.M., Sinclair R.D., Lenox J.B. Chemical and nonchemical components of ventilation during hypercapnic exercise in man. J. Appl. Physiol. 1980, 48:1065-1076.
8. Cunningham D.J. Studies on arterial chemoreceptors in man. J. Physiol. 1987, 384:1-26.
9. Dejours P., Labrousse Y., Raynaud J., Girard F., Teillac A. [Oxygen stimulation of respiration at rest and during muscular exercise at low altitude (50meters) in man]. Rev. Fr. Etud. Clin. Biol. 1958, 3:105-123.
10. Essfeld D., Hoffmann U., Stegemann J. Ventilatory effects of hypercapnic end-tidal PCO2 clamps during aerobic exercise of varying intensity. Eur. J. Appl. Physiol. Occup. Physiol. 1990, 60:412-417.
11. 2 during exercise. Annu. Rev. Physiol. 1983, 45:415-426.
12. Forster H.V. Exercise hyperpnea: where do we go from here?. Exerc. Sport Sci. Rev. 2000, 28:133-137.
13. 2 on the ventilatory sensitivity to rising body temperature during exercise. J. Appl. Physiol. 2011.
14. Honda Y., Myojo S., Hasegawa S., Hasegawa T., Severinghaus J.W. Decreased exercise hyperpnea in patients with bilateral carotid chemoreceptor resection. J. Appl. Physiol. 1979, 46:908-912.
15. Ide K., Horn A., Secher N.H. Cerebral metabolic response to submaximal exercise. J. Appl. Physiol. 1999, 87:1604-1608.
16. Jeyaranjan R., Goode R., Beamish S., Duffin J. The contribution of peripheral chemoreceptors to ventilation during heavy exercise. Respir. Physiol. 1987, 68:203-213.
17. Jones N.L., Robertson D.G., Kane J.W. Difference between end-tidal and arterial PCO2 in exercise. J. Appl. Physiol. 1979, 47:954-960.
18. Kobayashi T., Sakakibara Y., Masuda A., Ohdaira T., Honda Y. Contribution of peripheral chemoreceptor drive in exercise hyperpnea in humans. Appl. Human Sci. 1996, 15:259-266.
19. Koehle M.S., Giles L.V., Curtis A.N., Walsh M.L., White M.D. Performance of a compact end-tidal forcing system. Respir. Physiol. Neurobiol. 2009, 167:155-161.
20. Lugliani R., Whipp B.J., Seard C., Wasserman K. Effect of bilateral carotid-body resection on ventilatory control at rest and during exercise in man. New Engl. J. Med. 1971, 285:1105-1111.
21. 2 uptake during dynamic exercise. J. Appl. Physiol. 1993, 74:245-250.
22. Mateika J.H., Duffin J. A review of the control of breathing during exercise. Eur. J. Appl. Physiol. Occup. Physiol. 1995, 71:1-27.
23. 2 relationship during exercise in goats: role of carotid bodies. J. Appl. Physiol. 1984, 57:1894-1900.
24. Miyamoto Y., Niizeki K. Ventilatory responses during incremental exercise in men under hyperoxic conditions. Jpn. J. Physiol. 1995, 45:59-68.
25. Olin J.T., Dimmen A.C., Subudhi A.W., Roach R.C. Cerebral blood flow and oxygenation at maximal exercise: the effect of clamping carbon dioxide. Respir. Physiol. Neurobiol. 2010.
26. Olin J.T., Dimmen A.C., Subudhi A.W., Roach R.C. Cerebral blood flow and oxygenation at maximal exercise: the effect of clamping carbon dioxide. Respir. Physiol. Neurobiol. 2011, 175:176-180.
27. Pan L.G., Forster H.V., Bisgard G.E., Murphy C.L., Lowry T.F. Independence of exercise hyperpnea and acidosis during high-intensity exercise in ponies. J. Appl. Physiol. 1986, 60:1016-1024.
28. 2 and exercise hyperventilation: a critical reappraisal. Respir. Physiol. Neurobiol. 2006, 150:4-18.
29. Pianosi P., Marchione T. Hypoxic response is inversely related to degree of exercise hyperventilation. Respir. Physiol. 1995, 101:71-78.
30. Poon C.S., Greene J.G. Control of exercise hyperpnea during hypercapnia in humans. J. Appl. Physiol. 1985, 59:792-797.
31. Poon C.S., Tin C., Yu Y. Homeostasis of exercise hyperpnea and optimal sensorimotor integration: the internal model paradigm. Respir. Physiol. Neurobiol. 2007, 159:1-13. discussion 14-20.
32. Rasmussen P., Nielsen J., Overgaard M., Krogh-Madsen R., Gjedde A., Secher N.H., Petersen N.C. Reduced muscle activation during exercise related to brain oxygenation and metabolism in humans. J. Physiol. 2010, 588:1985-1995.
33. +] on ventilatory responses to exercise in the awake goat. J. Appl. Physiol. 1988, 65:921-927.
34. Smith S.A., Gallagher K.M., Norton K.H., Querry R.G., Welch-O'Connor R.M., Raven P.B. Ventilatory responses to dynamic exercise elicited by intramuscular sensors. Med. Sci. Sports Exerc. 1999, 31:277-286.
35. St Croix C.M., Cunningham D.A., Paterson D.H., Kowalchuk J.M. Peripheral chemoreflex drive in moderate-intensity exercise. Can. J. Appl. Physiol. 1996, 21:285-300.
36. Subudhi A.W., Lorenz M.C., Fulco C.S., Roach R.C. Cerebrovascular responses to incremental exercise during hypobaric hypoxia: effect of oxygenation on maximal performance. Am. J. Physiol. Heart Circ. Physiol. 2008, 294:H164-H171.
37. Takano N. Respiratory compensation point during incremental exercise as related to hypoxic ventilatory chemosensitivity and lactate increase in man. Jpn. J. Physiol. 2000, 50:449-455.
38. Tansley J.G., Clar C., Pedersen M.E., Robbins P.A. Human ventilatory response to acute hyperoxia during and after 8h of both isocapnic and poikilocapnic hypoxia. J. Appl. Physiol. 1997, 82:513-519.
39. Ward S.A. Control of the exercise hyperpnoea in humans: a modeling perspective. Respir. Physiol. 2000, 122:149-166.
40. Wasserman K. Testing regulation of ventilation with exercise. Chest 1976, 70:173-178.
41. + regulation during exercise in humans. Respir. Physiol. Neurobiol. 2011, 178:191-195.
42. Wasserman K., Whipp B.J., Koyal S.N., Cleary M.G. Effect of carotid body resection on ventilatory and acid-base control during exercise. J. Appl. Physiol. 1975, 39:354-358.
43. Weil J.V., Byrne-Quinn E., Sodal I.E., Kline J.S., McCullough R.E., Filley G.F. Augmentation of chemosensitivity during mild exercise in normal man. J. Appl. Physiol. 1972, 33:813-819.
44. Williamson J.W., Raven P.B., Foresman B.H., Whipp B.J. Evidence for an intramuscular ventilatory stimulus during dynamic exercise in man. Respir. Physiol. 1993, 94:121-135.