-
1
-
-
0035000004
-
Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line TT
-
Zatelli MC, Tagliati F, Taylor JE et al. Somatostatin receptor subtypes 2 and 5 differentially affect proliferation in vitro of the human medullary thyroid carcinoma cell line TT. J Clin Endocrinol Metab 2001; 86: 2161-9.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 2161-2169
-
-
Zatelli, M.C.1
Tagliati, F.2
Taylor, J.E.3
-
2
-
-
0035989072
-
Somatostatin, but not somatostatin receptor subtypes 2 and 5 selective agonists, inhibits calcitonin secretion and gene expression in the human medullary thyroid carcinoma cell line, TT
-
Zatelli MC, Tagliati F, Taylor JE et al. Somatostatin, but not somatostatin receptor subtypes 2 and 5 selective agonists, inhibits calcitonin secretion and gene expression in the human medullary thyroid carcinoma cell line, TT. Horm Metab Res 2002; 5: 229-33.
-
(2002)
Horm Metab Res
, vol.5
, pp. 229-233
-
-
Zatelli, M.C.1
Tagliati, F.2
Taylor, J.E.3
-
3
-
-
0031784575
-
Somatostatin and somatostatin receptor subtype gene expression in medullary thyroid carcinoma
-
Mato E, Matias-Guiu X, Chico A et al. Somatostatin and somatostatin receptor subtype gene expression in medullary thyroid carcinoma. J Clini Endocrinol Metab 1998; 83: 2417-20.
-
(1998)
J Clini Endocrinol Metab
, vol.83
, pp. 2417-2420
-
-
Mato, E.1
Matias-Guiu, X.2
Chico, A.3
-
4
-
-
30344439815
-
Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer
-
Strock CJ, Park JI, Rosen DM et al. Activity of irinotecan and the tyrosine kinase inhibitor CEP-751 in medullary thyroid cancer. J Clin Endocrinol Metab 2006; 91: 79-84.
-
(2006)
J Clin Endocrinol Metab
, vol.91
, pp. 79-84
-
-
Strock, C.J.1
Park, J.I.2
Rosen, D.M.3
-
5
-
-
77956114179
-
Combination of RET siRNA and irinotecan inhibited the growth of medullary thyroid carcinoma TT cells and xenografts via apoptosis
-
Koga K, Hattori Y, Komori M et al. Combination of RET siRNA and irinotecan inhibited the growth of medullary thyroid carcinoma TT cells and xenografts via apoptosis. Cancer Sci 2010; 101: 941-7.
-
(2010)
Cancer Sci
, vol.101
, pp. 941-947
-
-
Koga, K.1
Hattori, Y.2
Komori, M.3
-
6
-
-
0025996996
-
Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11
-
Kawato Y, Aonuma M, Hirota Y et al. Intracellular roles of SN-38, a metabolite of the camptothecin derivative CPT-11, in the antitumor effect of CPT-11. Cancer Res 1991; 51: 4187-91.
-
(1991)
Cancer Res
, vol.51
, pp. 4187-4191
-
-
Kawato, Y.1
Aonuma, M.2
Hirota, Y.3
-
7
-
-
0025785082
-
Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice
-
Kawato Y, Furuta T, Aonuma M et al. Antitumor activity of a camptothecin derivative, CPT-11, against human tumor xenografts in nude mice. Cancer Chemother Pharmacol 1991; 28: 192-8.
-
(1991)
Cancer Chemother Pharmacol
, vol.28
, pp. 192-198
-
-
Kawato, Y.1
Furuta, T.2
Aonuma, M.3
-
8
-
-
0024010012
-
Topoisomerases: novel therapeutic targets in cancer chemotherapy
-
Hsiang YH, Wu HY, Liu LF. Topoisomerases: novel therapeutic targets in cancer chemotherapy. Biochem Pharmacol 1988; 37: 1801-2.
-
(1988)
Biochem Pharmacol
, vol.37
, pp. 1801-1802
-
-
Hsiang, Y.H.1
Wu, H.Y.2
Liu, L.F.3
-
9
-
-
0023924786
-
Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin
-
Hsiang YH, Liu LF. Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin. Cancer Res 1988; 48: 1722-6.
-
(1988)
Cancer Res
, vol.48
, pp. 1722-1726
-
-
Hsiang, Y.H.1
Liu, L.F.2
-
10
-
-
0024420685
-
Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin
-
Hsiang YH, Lihou MG, Liu LF. Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin. Cancer Res 1989; 49: 5077-82.
-
(1989)
Cancer Res
, vol.49
, pp. 5077-5082
-
-
Hsiang, Y.H.1
Lihou, M.G.2
Liu, L.F.3
-
11
-
-
0029931995
-
Preclinical evaluation of CPT-11 and its active metabolite SN-38
-
Lavelle F, Bissery MC, Andre S et al. Preclinical evaluation of CPT-11 and its active metabolite SN-38. Semin Oncol 1996; 23: 11-20.
-
(1996)
Semin Oncol
, vol.23
, pp. 11-20
-
-
Lavelle, F.1
Bissery, M.C.2
Andre, S.3
-
12
-
-
53849134827
-
Somatostatin analogues in the control of neuroendocrine tumours: efficacy and mechanisms
-
Grozinsky-Glasberg S, Shimon I, Korbonits M et al. Somatostatin analogues in the control of neuroendocrine tumours: efficacy and mechanisms. Endocr-Relat Cancer 2008; 15: 701-20.
-
(2008)
Endocr-Relat Cancer
, vol.15
, pp. 701-720
-
-
Grozinsky-Glasberg, S.1
Shimon, I.2
Korbonits, M.3
-
13
-
-
79953821130
-
Octreotide-targeted liposomes loaded with CPT-11 enhanced cytotoxicity for the treatment of medullary thyroid carcinoma
-
Iwase Y, Maitani Y. Octreotide-targeted liposomes loaded with CPT-11 enhanced cytotoxicity for the treatment of medullary thyroid carcinoma. Mol Pharm 2011; 8: 330-7.
-
(2011)
Mol Pharm
, vol.8
, pp. 330-337
-
-
Iwase, Y.1
Maitani, Y.2
-
14
-
-
0022858683
-
New concept for macromolecular therapeutics in cancer chemotherapy mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs
-
Matsumura Y, Maeda HA. New concept for macromolecular therapeutics in cancer chemotherapy mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res 1986; 46: 6387-92.
-
(1986)
Cancer Res
, vol.46
, pp. 6387-6392
-
-
Matsumura, Y.1
Maeda, H.A.2
-
15
-
-
42449118823
-
Octreotide and the mTOR inhibitor RAD001 (Everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumor cell line
-
Grozinsky-Glasberg S, Franchi G, Teng M et al. Octreotide and the mTOR inhibitor RAD001 (Everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumor cell line. Neuroendocrinolgy 2008; 87: 168-81.
-
(2008)
Neuroendocrinolgy
, vol.87
, pp. 168-181
-
-
Grozinsky-Glasberg, S.1
Franchi, G.2
Teng, M.3
-
16
-
-
48849104242
-
A synthetic method for peptide-PEG-lipid conjugates: application of Octreotide-PEG-DSPE synthesis
-
Su JC, Tseng CL, Chang TG et al. A synthetic method for peptide-PEG-lipid conjugates: application of Octreotide-PEG-DSPE synthesis. Bioorg Med Chem Let 2008; 18: 4593-6.
-
(2008)
Bioorg Med Chem Let
, vol.18
, pp. 4593-4596
-
-
Su, J.C.1
Tseng, C.L.2
Chang, T.G.3
-
17
-
-
67349152765
-
Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors
-
Hattori Y, Shi L, Ding W et al. Novel irinotecan-loaded liposome using phytic acid with high therapeutic efficacy for colon tumors. J Control Release 2009; 136: 30-7.
-
(2009)
J Control Release
, vol.136
, pp. 30-37
-
-
Hattori, Y.1
Shi, L.2
Ding, W.3
-
18
-
-
0032926512
-
CPT-11 converting carboxylesterase and topoisomerase activities in tumour and normal colon and liver tissues
-
Guichard S, Terret C, Hennebelle I et al. CPT-11 converting carboxylesterase and topoisomerase activities in tumour and normal colon and liver tissues. Br J Cancer 1999; 80: 364-70.
-
(1999)
Br J Cancer
, vol.80
, pp. 364-370
-
-
Guichard, S.1
Terret, C.2
Hennebelle, I.3
-
19
-
-
57349096726
-
NaCl induced high cationic hydroxyethylated cholesterol-based nanoparticle-mediated synthetic small interfering RNA transfer into prostate carcinoma PC-3 cells
-
Hattori Y, Yoshizawa T, Koga K et al. NaCl induced high cationic hydroxyethylated cholesterol-based nanoparticle-mediated synthetic small interfering RNA transfer into prostate carcinoma PC-3 cells. Biol Pharm Bull 2008; 31: 2294-301.
-
(2008)
Biol Pharm Bull
, vol.31
, pp. 2294-2301
-
-
Hattori, Y.1
Yoshizawa, T.2
Koga, K.3
-
20
-
-
27844445642
-
Perturbations of the AKT signaling pathway in human cancer
-
Altomare DA, Testa JR. Perturbations of the AKT signaling pathway in human cancer. Oncogene 2005; 24: 7455-64.
-
(2005)
Oncogene
, vol.24
, pp. 7455-7464
-
-
Altomare, D.A.1
Testa, J.R.2
-
21
-
-
0001457668
-
Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA
-
Cheng JQ, Ruggeri B, Klein WM et al. Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA. Proc Natl Acad Sci USA 1996; 93: 3636-41.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 3636-3641
-
-
Cheng, J.Q.1
Ruggeri, B.2
Klein, W.M.3
-
22
-
-
12144288657
-
Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer
-
Vasko V, Saji M, Hardy E et al. Akt activation and localisation correlate with tumour invasion and oncogene expression in thyroid cancer. J Med Genet 2004; 41: 161-70.
-
(2004)
J Med Genet
, vol.41
, pp. 161-170
-
-
Vasko, V.1
Saji, M.2
Hardy, E.3
-
23
-
-
23944526062
-
Activation of AKT kinases in cancer: implications for therapeutic targeting
-
Bellacosa A, Kumar CC, Di Cristofano A et al. Activation of AKT kinases in cancer: implications for therapeutic targeting. Adv Cancer Res 2005; 94: 29-86.
-
(2005)
Adv Cancer Res
, vol.94
, pp. 29-86
-
-
Bellacosa, A.1
Kumar, C.C.2
Di Cristofano, A.3
-
24
-
-
33947538812
-
Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway is essential for neuroendocrine differentiation of prostate cancer
-
Wu C, Huang J. Phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway is essential for neuroendocrine differentiation of prostate cancer. J Biol Chem 2007; 282: 3571-83.
-
(2007)
J Biol Chem
, vol.282
, pp. 3571-3583
-
-
Wu, C.1
Huang, J.2
-
25
-
-
0036712741
-
TSC1-TSC2: a complex tale of PKB-mediated S6K regulation
-
McManus EJ, Alessi DR. TSC1-TSC2: a complex tale of PKB-mediated S6K regulation. Nature Cell Biol 2002; 4: E214-16.
-
(2002)
Nature Cell Biol
, vol.4
-
-
McManus, E.J.1
Alessi, D.R.2
-
26
-
-
0030580064
-
Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase
-
Rivory LP, Bowles MR, Robert J et al. Conversion of irinotecan (CPT-11) to its active metabolite, 7-ethyl-10-hydroxycamptothecin (SN-38), by human liver carboxylesterase. Biochem Pharmacol 1996; 52: 1103-11.
-
(1996)
Biochem Pharmacol
, vol.52
, pp. 1103-1111
-
-
Rivory, L.P.1
Bowles, M.R.2
Robert, J.3
-
28
-
-
9144233506
-
Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells
-
Boulay A, Zumstein-Mecker S, Stephan C et al. Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells. Cancer Res 2004; 64: 252-61.
-
(2004)
Cancer Res
, vol.64
, pp. 252-261
-
-
Boulay, A.1
Zumstein-Mecker, S.2
Stephan, C.3
-
29
-
-
0026505393
-
Results of long-term continuous subcutaneous octreotide administration in 14 patients with medullary thyroid carcinoma
-
Modigliani E, Cohen R, Joannidis S et al. Results of long-term continuous subcutaneous octreotide administration in 14 patients with medullary thyroid carcinoma. Clin Endocrinol 1992; 36: 183-6.
-
(1992)
Clin Endocrinol
, vol.36
, pp. 183-186
-
-
Modigliani, E.1
Cohen, R.2
Joannidis, S.3
-
30
-
-
0029794479
-
Treatment of advanced medullary thyroid carcinoma with a combination of recombinant interferon alpha-2b and octreotide
-
Lupoli G, Cascone E, Arlotta F et al. Treatment of advanced medullary thyroid carcinoma with a combination of recombinant interferon alpha-2b and octreotide. Cancer 1996; 78: 1114-8.
-
(1996)
Cancer
, vol.78
, pp. 1114-1118
-
-
Lupoli, G.1
Cascone, E.2
Arlotta, F.3
|