-
1
-
-
0031827634
-
Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types
-
Srinivasan R., Poulsom R., Hurst H.C., Gullick W.J. Expression of the c-erbB-4/HER4 protein and mRNA in normal human fetal and adult tissues and in a survey of nine solid tumour types. J. Pathol. 1998, 185:236-245.
-
(1998)
J. Pathol.
, vol.185
, pp. 236-245
-
-
Srinivasan, R.1
Poulsom, R.2
Hurst, H.C.3
Gullick, W.J.4
-
2
-
-
0037429722
-
ErbB-4: mechanism of action and biology
-
Carpenter G. ErbB-4: mechanism of action and biology. Exp. Cell Res. 2003, 284:66-77.
-
(2003)
Exp. Cell Res.
, vol.284
, pp. 66-77
-
-
Carpenter, G.1
-
3
-
-
0028785406
-
Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor
-
Gassmann M., Casagranda F., Orioli D., Simon H., Lai C., Klein R., Lemke G. Aberrant neural and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 1995, 378:390-394.
-
(1995)
Nature
, vol.378
, pp. 390-394
-
-
Gassmann, M.1
Casagranda, F.2
Orioli, D.3
Simon, H.4
Lai, C.5
Klein, R.6
Lemke, G.7
-
4
-
-
23944477855
-
Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle
-
Garcia-Rivello H., Taranda J., Said M., Cabeza-Meckert P., Vila-Petroff M., Scaglione J., Ghio S., Chen J., Lai C., Laguens R.P., Lloyd K.C., Hertig C.M. Dilated cardiomyopathy in Erb-b4-deficient ventricular muscle. Am. J. Physiol. Heart Circ. Physiol. 2005, 289:H1153-H1160.
-
(2005)
Am. J. Physiol. Heart Circ. Physiol.
, vol.289
-
-
Garcia-Rivello, H.1
Taranda, J.2
Said, M.3
Cabeza-Meckert, P.4
Vila-Petroff, M.5
Scaglione, J.6
Ghio, S.7
Chen, J.8
Lai, C.9
Laguens, R.P.10
Lloyd, K.C.11
Hertig, C.M.12
-
5
-
-
0344924865
-
Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt
-
Fukazawa R., Miller T.A., Kuramochi Y., Frantz S., Kim Y.D., Marchionni M.A., Kelly R.A., Sawyer D.B. Neuregulin-1 protects ventricular myocytes from anthracycline-induced apoptosis via erbB4-dependent activation of PI3-kinase/Akt. J. Mol. Cell. Cardiol. 2003, 35:1473-1479.
-
(2003)
J. Mol. Cell. Cardiol.
, vol.35
, pp. 1473-1479
-
-
Fukazawa, R.1
Miller, T.A.2
Kuramochi, Y.3
Frantz, S.4
Kim, Y.D.5
Marchionni, M.A.6
Kelly, R.A.7
Sawyer, D.B.8
-
6
-
-
10944236872
-
Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling
-
Kuramochi Y., Cote G.M., Guo X., Lebrasseur N.K., Cui L., Liao R., Sawyer D.B. Cardiac endothelial cells regulate reactive oxygen species-induced cardiomyocyte apoptosis through neuregulin-1beta/erbB4 signaling. J. Biol. Chem. 2004, 279:51141-51147.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 51141-51147
-
-
Kuramochi, Y.1
Cote, G.M.2
Guo, X.3
Lebrasseur, N.K.4
Cui, L.5
Liao, R.6
Sawyer, D.B.7
-
7
-
-
0030685131
-
A novel juxta membrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester
-
Elenius K., Corfas G., Paul S., Choi C.J., Rio C., Plowman G.D., Klagsbrun M. A novel juxta membrane domain isoform of HER4/ErbB4. Isoform-specific tissue distribution and differential processing in response to phorbol ester. J. Biol. Chem. 1997, 272:26761-26768.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 26761-26768
-
-
Elenius, K.1
Corfas, G.2
Paul, S.3
Choi, C.J.4
Rio, C.5
Plowman, G.D.6
Klagsbrun, M.7
-
8
-
-
0037155219
-
Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4
-
Lee H.J., Jung K.M., Huang Y.Z., Bennett L.B., Lee J.S., Mei L., Kim T.W. Presenilin-dependent gamma-secretase-like intramembrane cleavage of ErbB4. J. Biol. Chem. 2002, 277:6318-6323.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 6318-6323
-
-
Lee, H.J.1
Jung, K.M.2
Huang, Y.Z.3
Bennett, L.B.4
Lee, J.S.5
Mei, L.6
Kim, T.W.7
-
9
-
-
0029764504
-
Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation
-
Vecchi M., Baulida J., Carpenter G. Selective cleavage of the heregulin receptor ErbB-4 by protein kinase C activation. J. Biol. Chem. 1996, 271:18989-18995.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 18989-18995
-
-
Vecchi, M.1
Baulida, J.2
Carpenter, G.3
-
10
-
-
24744450988
-
Secretase-dependent tyrosine phosphorylation of Mdm2 by the ErbB-4 intracellular domain fragment
-
Arasada R.R., Carpenter G. Secretase-dependent tyrosine phosphorylation of Mdm2 by the ErbB-4 intracellular domain fragment. J. Biol. Chem. 2005, 280:30783-30787.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 30783-30787
-
-
Arasada, R.R.1
Carpenter, G.2
-
11
-
-
0035824391
-
Gamma-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase
-
Ni C.Y., Murphy M.P., Golde T.E., Carpenter G. Gamma-Secretase cleavage and nuclear localization of ErbB-4 receptor tyrosine kinase. Science 2001, 294:2179-2181.
-
(2001)
Science
, vol.294
, pp. 2179-2181
-
-
Ni, C.Y.1
Murphy, M.P.2
Golde, T.E.3
Carpenter, G.4
-
12
-
-
21244487829
-
Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities
-
Vidal G.A., Naresh A., Marrero L., Jones F.E. Presenilin-dependent gamma-secretase processing regulates multiple ERBB4/HER4 activities. J. Biol. Chem. 2005, 280:19777-19783.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 19777-19783
-
-
Vidal, G.A.1
Naresh, A.2
Marrero, L.3
Jones, F.E.4
-
13
-
-
0035736487
-
HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation
-
Zhou B.P., Liao Y., Xia W., Zou Y., Spohn B., Hung M.C. HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation. Nat. Cell Biol. 2001, 3:973-982.
-
(2001)
Nat. Cell Biol.
, vol.3
, pp. 973-982
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Zou, Y.4
Spohn, B.5
Hung, M.C.6
-
14
-
-
0032578406
-
Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway
-
Communal C., Singh K., Pimentel D.R., Colucci W.S. Norepinephrine stimulates apoptosis in adult rat ventricular myocytes by activation of the beta-adrenergic pathway. Circulation 1998, 98:1329-1334.
-
(1998)
Circulation
, vol.98
, pp. 1329-1334
-
-
Communal, C.1
Singh, K.2
Pimentel, D.R.3
Colucci, W.S.4
-
15
-
-
0027468890
-
Isolation and characterization of human and rat cardiac microvascular endothelial cells
-
Nishida M., Carley W.W., Gerritsen M.E., Ellingsen O., Kelly R.A., Smith T.W. Isolation and characterization of human and rat cardiac microvascular endothelial cells. Am. J. Physiol. 1993, 264:H639-H652.
-
(1993)
Am. J. Physiol.
, vol.264
-
-
Nishida, M.1
Carley, W.W.2
Gerritsen, M.E.3
Ellingsen, O.4
Kelly, R.A.5
Smith, T.W.6
-
16
-
-
33745714207
-
The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells
-
Naresh A., Long W., Vidal G.A., Wimley W.C., Marrero L., Sartor C.I., Tovey S., Cooke T.G., Bartlett J.M., Jones F.E. The ERBB4/HER4 intracellular domain 4ICD is a BH3-only protein promoting apoptosis of breast cancer cells. Cancer Res. 2006, 66:6412-6420.
-
(2006)
Cancer Res.
, vol.66
, pp. 6412-6420
-
-
Naresh, A.1
Long, W.2
Vidal, G.A.3
Wimley, W.C.4
Marrero, L.5
Sartor, C.I.6
Tovey, S.7
Cooke, T.G.8
Bartlett, J.M.9
Jones, F.E.10
-
17
-
-
3242880238
-
H2AX: the histone guardian of the genome
-
Fernandez-Capetillo O., Lee A., Nussenzweig M., Nussenzweig A. H2AX: the histone guardian of the genome. DNA Repair (Amst.) 2004, 3:959-967.
-
(2004)
DNA Repair (Amst.)
, vol.3
, pp. 959-967
-
-
Fernandez-Capetillo, O.1
Lee, A.2
Nussenzweig, M.3
Nussenzweig, A.4
-
18
-
-
20444391346
-
Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair
-
Thiriet C., Hayes J.J. Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. Mol. Cell 2005, 18:617-622.
-
(2005)
Mol. Cell
, vol.18
, pp. 617-622
-
-
Thiriet, C.1
Hayes, J.J.2
-
19
-
-
0030667702
-
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
-
Shieh S.Y., Ikeda M., Taya Y., Prives C. DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 1997, 91:325-334.
-
(1997)
Cell
, vol.91
, pp. 325-334
-
-
Shieh, S.Y.1
Ikeda, M.2
Taya, Y.3
Prives, C.4
-
20
-
-
0031435944
-
DNA damage induces phosphorylation of the amino terminus of p53
-
Siliciano J.D., Canman C.E., Taya Y., Sakaguchi K., Appella E., Kastan M.B. DNA damage induces phosphorylation of the amino terminus of p53. Genes Dev. 1997, 11:3471-3481.
-
(1997)
Genes Dev.
, vol.11
, pp. 3471-3481
-
-
Siliciano, J.D.1
Canman, C.E.2
Taya, Y.3
Sakaguchi, K.4
Appella, E.5
Kastan, M.B.6
-
21
-
-
0033118933
-
DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization
-
Shieh S.Y., Taya Y., Prives C. DNA damage-inducible phosphorylation of p53 at N-terminal sites including a novel site, Ser20, requires tetramerization. Embo J. 1999, 18:1815-1823.
-
(1999)
Embo J.
, vol.18
, pp. 1815-1823
-
-
Shieh, S.Y.1
Taya, Y.2
Prives, C.3
-
22
-
-
0032530486
-
DNA damage activates p53 through a phosphorylation-acetylation cascade
-
Sakaguchi K., Herrera J.E., Saito S., Miki T., Bustin M., Vassilev A., Anderson C.W., Appella E. DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev. 1998, 12:2831-2841.
-
(1998)
Genes Dev.
, vol.12
, pp. 2831-2841
-
-
Sakaguchi, K.1
Herrera, J.E.2
Saito, S.3
Miki, T.4
Bustin, M.5
Vassilev, A.6
Anderson, C.W.7
Appella, E.8
-
23
-
-
0032508504
-
Enhanced phosphorylation of p53 by ATM in response to DNA damage
-
Banin S., Moyal L., Shieh S., Taya Y., Anderson C.W., Chessa L., Smorodinsky N.I., Prives C., Reiss Y., Shiloh Y., Ziv Y. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 1998, 281:1674-1677.
-
(1998)
Science
, vol.281
, pp. 1674-1677
-
-
Banin, S.1
Moyal, L.2
Shieh, S.3
Taya, Y.4
Anderson, C.W.5
Chessa, L.6
Smorodinsky, N.I.7
Prives, C.8
Reiss, Y.9
Shiloh, Y.10
Ziv, Y.11
-
24
-
-
0033572746
-
Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2
-
Dumaz N., Meek D.W. Serine15 phosphorylation stimulates p53 transactivation but does not directly influence interaction with HDM2. Embo J. 1999, 18:7002-7010.
-
(1999)
Embo J.
, vol.18
, pp. 7002-7010
-
-
Dumaz, N.1
Meek, D.W.2
-
25
-
-
0037329056
-
The p53-Mdm2 module and the ubiquitin system
-
Michael D., Oren M. The p53-Mdm2 module and the ubiquitin system. Semin. Cancer Biol. 2003, 13:49-58.
-
(2003)
Semin. Cancer Biol.
, vol.13
, pp. 49-58
-
-
Michael, D.1
Oren, M.2
-
26
-
-
0030905284
-
Mdm2 promotes the rapid degradation of p53
-
Haupt Y., Maya R., Kazaz A., Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997, 387:296-299.
-
(1997)
Nature
, vol.387
, pp. 296-299
-
-
Haupt, Y.1
Maya, R.2
Kazaz, A.3
Oren, M.4
-
27
-
-
0037077230
-
Akt enhances Mdm2-mediated ubiquitination and degradation of p53
-
Ogawara Y., Kishishita S., Obata T., Isazawa Y., Suzuki T., Tanaka K., Masuyama N., Gotoh Y. Akt enhances Mdm2-mediated ubiquitination and degradation of p53. J. Biol. Chem. 2002, 277:21843-21850.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21843-21850
-
-
Ogawara, Y.1
Kishishita, S.2
Obata, T.3
Isazawa, Y.4
Suzuki, T.5
Tanaka, K.6
Masuyama, N.7
Gotoh, Y.8
-
28
-
-
0028827104
-
Multiple essential functions of neuregulin in development
-
Meyer D., Birchmeier C. Multiple essential functions of neuregulin in development. Nature 1995, 378:386-390.
-
(1995)
Nature
, vol.378
, pp. 386-390
-
-
Meyer, D.1
Birchmeier, C.2
-
29
-
-
0032562770
-
Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes
-
Zhao Y.Y., Sawyer D.R., Baliga R.R., Opel D.J., Han X., Marchionni M.A., Kelly R.A. Neuregulins promote survival and growth of cardiac myocytes. Persistence of ErbB2 and ErbB4 expression in neonatal and adult ventricular myocytes. J. Biol. Chem. 1998, 273:10261-10269.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10261-10269
-
-
Zhao, Y.Y.1
Sawyer, D.R.2
Baliga, R.R.3
Opel, D.J.4
Han, X.5
Marchionni, M.A.6
Kelly, R.A.7
-
30
-
-
0034616385
-
Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4
-
Rio C., Buxbaum J.D., Peschon J.J., Corfas G. Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4. J. Biol. Chem. 2000, 275:10379-10387.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 10379-10387
-
-
Rio, C.1
Buxbaum, J.D.2
Peschon, J.J.3
Corfas, G.4
-
31
-
-
0042858208
-
WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus
-
Komuro A., Nagai M., Navin N.E., Sudol M. WW domain-containing protein YAP associates with ErbB-4 and acts as a co-transcriptional activator for the carboxyl-terminal fragment of ErbB-4 that translocates to the nucleus. J. Biol. Chem. 2003, 278:33334-33341.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 33334-33341
-
-
Komuro, A.1
Nagai, M.2
Navin, N.E.3
Sudol, M.4
-
32
-
-
0037445982
-
Nuclear trafficking of FGFR1: a role for the transmembrane domain
-
Myers J.M., Martins G.G., Ostrowski J., Stachowiak M.K. Nuclear trafficking of FGFR1: a role for the transmembrane domain. J. Cell. Biochem. 2003, 88:1273-1291.
-
(2003)
J. Cell. Biochem.
, vol.88
, pp. 1273-1291
-
-
Myers, J.M.1
Martins, G.G.2
Ostrowski, J.3
Stachowiak, M.K.4
-
33
-
-
0029082963
-
Acinar and cellular distribution and mRNA expression of the epidermal growth factor receptor are changed during liver regeneration
-
Marti U., Hug M. Acinar and cellular distribution and mRNA expression of the epidermal growth factor receptor are changed during liver regeneration. J. Hepatol. 1995, 23:318-327.
-
(1995)
J. Hepatol.
, vol.23
, pp. 318-327
-
-
Marti, U.1
Hug, M.2
-
34
-
-
28444453967
-
Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity
-
Dittmann K., Mayer C., Rodemann H.P. Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity. Radiother. Oncol. 2005, 76:157-161.
-
(2005)
Radiother. Oncol.
, vol.76
, pp. 157-161
-
-
Dittmann, K.1
Mayer, C.2
Rodemann, H.P.3
-
35
-
-
24744449739
-
Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase
-
Dittmann K., Mayer C., Fehrenbacher B., Schaller M., Raju U., Milas L., Chen D.J., Kehlbach R., Rodemann H.P. Radiation-induced epidermal growth factor receptor nuclear import is linked to activation of DNA-dependent protein kinase. J. Biol. Chem. 2005, 280:31182-31189.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 31182-31189
-
-
Dittmann, K.1
Mayer, C.2
Fehrenbacher, B.3
Schaller, M.4
Raju, U.5
Milas, L.6
Chen, D.J.7
Kehlbach, R.8
Rodemann, H.P.9
-
36
-
-
33846479961
-
Stimulated ErbB4 internalization is necessary for neuregulin signaling in neurons
-
Liu Y., Tao Y.M., Woo R.S., Xiong W.C., Mei L. Stimulated ErbB4 internalization is necessary for neuregulin signaling in neurons. Biochem. Biophys. Res. Commun. 2007, 354:505-510.
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.354
, pp. 505-510
-
-
Liu, Y.1
Tao, Y.M.2
Woo, R.S.3
Xiong, W.C.4
Mei, L.5
-
37
-
-
28544448741
-
Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor
-
Giri D.K., Ali-Seyed M., Li L.Y., Lee D.F., Ling P., Bartholomeusz G., Wang S.C., Hung M.C. Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor. Mol. Cell. Biol. 2005, 25:11005-11018.
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 11005-11018
-
-
Giri, D.K.1
Ali-Seyed, M.2
Li, L.Y.3
Lee, D.F.4
Ling, P.5
Bartholomeusz, G.6
Wang, S.C.7
Hung, M.C.8
-
38
-
-
33947118714
-
Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression
-
Liao H.J., Carpenter G. Role of the Sec61 translocon in EGF receptor trafficking to the nucleus and gene expression. Mol. Biol. Cell 2007, 18:1064-1072.
-
(2007)
Mol. Biol. Cell
, vol.18
, pp. 1064-1072
-
-
Liao, H.J.1
Carpenter, G.2
-
39
-
-
62649116580
-
The role of Neuregulin-1beta/ErbB signaling in the heart
-
Pentassuglia L., Sawyer D.B. The role of Neuregulin-1beta/ErbB signaling in the heart. Exp. Cell Res. 2009, 315:627-637.
-
(2009)
Exp. Cell Res.
, vol.315
, pp. 627-637
-
-
Pentassuglia, L.1
Sawyer, D.B.2
-
40
-
-
1942434712
-
Cip/Kip proteins: more than just CDKs inhibitors
-
Denicourt C., Dowdy S.F. Cip/Kip proteins: more than just CDKs inhibitors. Genes Dev. 2004, 18:851-855.
-
(2004)
Genes Dev.
, vol.18
, pp. 851-855
-
-
Denicourt, C.1
Dowdy, S.F.2
-
41
-
-
0023858067
-
Abrogation of etoposide-mediated cytotoxicity by cycloheximide
-
Chow K.C., King C.K., Ross W.E. Abrogation of etoposide-mediated cytotoxicity by cycloheximide. Biochem. Pharmacol. 1988, 37:1117-1122.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 1117-1122
-
-
Chow, K.C.1
King, C.K.2
Ross, W.E.3
-
42
-
-
0026576779
-
Abrogation of adriamycin toxicity in vivo by cycloheximide
-
Thakkar N.S., Potten C.S. Abrogation of adriamycin toxicity in vivo by cycloheximide. Biochem. Pharmacol. 1992, 43:1683-1691.
-
(1992)
Biochem. Pharmacol.
, vol.43
, pp. 1683-1691
-
-
Thakkar, N.S.1
Potten, C.S.2
-
43
-
-
0027255657
-
Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose
-
Thakkar N.S., Potten C.S. Inhibition of doxorubicin-induced apoptosis in vivo by 2-deoxy-D-glucose. Cancer Res. 1993, 53:2057-2060.
-
(1993)
Cancer Res.
, vol.53
, pp. 2057-2060
-
-
Thakkar, N.S.1
Potten, C.S.2
|