Interaction between filaggrin null mutations and tobacco smoking in relation to asthma

Journal of Allergy and Clinical Immunology

Volumn 129, Issue 2, 2012, Pages

  Berg, Nikolaj Drimer ^a   Husemoen, Lise Lotte N ^a   Thuesen, Betina Heinsbæk ^a   Hersoug, Lars Georg ^a   Elberling, Jesper ^b   Thyssen, Jacob Pontoppidan ^b   Carlsen, Berit Christina ^b   Johansen, Jeanne Duus ^b   Menné, Torkil ^b   Bønnelykke, Klaus ^c   Stender, Steen ^b   Meldgaard, Michael ^b   Szecsi, Pal Bela ^b   Linneberg, Allan ^a  

^a GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

^b GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

2282del4; Asthma; filaggrin; gene environment interaction; genotype; health examination; Health2006; population based; R501X; tobacco smoking

Indexed keywords

FILAGGRIN; IMMUNOGLOBULIN E; NITRIC OXIDE;

ARTICLE; ASTHMA; ATOPIC DERMATITIS; ATOPY; COUGHING; DENMARK; DISEASE ASSOCIATION; ENVIRONMENTAL EXPOSURE; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; GENOTYPE PHENOTYPE CORRELATION; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; LUNG FUNCTION TEST; MAJOR CLINICAL STUDY; MALE; NULL ALLELE; PRIORITY JOURNAL; SMOKING; SPIROMETRY; TOBACCO; WHEEZING;

EID: 84856460075     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2011.08.045     Document Type: Article

References (44)

1. E. Proksch, J.M. Brandner, and J.M. Jensen The skin: an indispensable barrier Exp Dermatol 17 2008 1063 1072
2. A. Sandilands, C. Sutherland, A.D. Irvine, and W.H. McLean Filaggrin in the frontline: role in skin barrier function and disease J Cell Sci 122 2009 1285 1294
3. D. Mischke, B.P. Korge, I. Marenholz, A. Volz, and A. Ziegler Genes encoding structural proteins of epidermal cornification and S100 calcium-binding proteins form a gene complex ("epidermal differentiation complex") on human chromosome 1q21 J Invest Dermatol 106 1996 989 992
4. F.J. Smith, A.D. Irvine, A. Terron-Kwiatkowski, A. Sandilands, L.E. Campbell, and Y. Zhao Loss-of-function mutations in the gene encoding filaggrin cause ichthyosis vulgaris Nat Genet 38 2006 337 342
5. P.G. Fallon, T. Sasaki, A. Sandilands, L.E. Campbell, S.P. Saunders, and N.E. Mangan A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming Nat Genet 41 2009 602 608
6. M.K. Oyoshi, G.F. Murphy, and R.S. Geha Filaggrin-deficient mice exhibit TH17-dominated skin inflammation and permissiveness to epicutaneous sensitization with protein antigen J Allergy Clin Immunol 124 2009 485 493
7. T.C. Scharschmidt, M.Q. Man, Y. Hatano, D. Crumrine, R. Gunathilake, and J.P. Sundberg Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens J Allergy Clin Immunol 124 2009 496 506
8. A. Sandilands, A. Terron-Kwiatkowski, P.R. Hull, G.M. O'Regan, T.H. Clayton, and R.M. Watson Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema Nat Genet 39 2007 650 654
9. C.N. Palmer, A.D. Irvine, A. Terron-Kwiatkowski, Y. Zhao, H. Liao, and S.P. Lee Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis Nat Genet 38 2006 441 446
10. E. Rodriguez, H. Baurecht, E. Herberich, S. Wagenpfeil, S.J. Brown, and H.J. Cordell Meta-analysis of filaggrin polymorphisms in eczema and asthma: robust risk factors in atopic disease J Allergy Clin Immunol 123 2009 1361 1370
11. R.A. van den Oord, and A. Sheikh Filaggrin gene defects and risk of developing allergic sensitisation and allergic disorders: systematic review and meta-analysis BMJ 339 2009 b2433
12. C.N. Palmer, T. Ismail, S.P. Lee, A. Terron-Kwiatkowski, Y. Zhao, and H. Liao Filaggrin null mutations are associated with increased asthma severity in children and young adults J Allergy Clin Immunol 120 2007 64 68
13. I. Kimber The role of the skin in the development of chemical respiratory hypersensitivity Toxicol Lett 86 1996 89 92
14. C.A. Redlich Skin exposure and asthma: is there a connection? Proc Am Thorac Soc 7 2010 134 137
15. E.L. Petsonk, M.L. Wang, D.M. Lewis, P.D. Siegel, and B.J. Husberg Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate Chest 118 2000 1183 1193
16. K. Shahzad, S. Akhtar, and S. Mahmud Prevalence and determinants of asthma in adult male leather tannery workers in Karachi, Pakistan: a cross sectional study BMC Public Health 6 2006 292
17. H. Bisgaard, A. Simpson, C.N. Palmer, K. Bonnelykke, I. McLean, and S. Mukhopadhyay Gene-environment interaction in the onset of eczema in infancy: filaggrin loss-of-function mutations enhanced by neonatal cat exposure PLoS Med 5 2008 e131
18. M.L. Schuttelaar, M. Kerkhof, M.F. Jonkman, G.H. Koppelman, B. Brunekreef, and J.C. de Jongste Filaggrin mutations in the onset of eczema, sensitization, asthma, hay fever and the interaction with cat exposure Allergy 64 2009 1758 1765
19. A.C. McLeish, and M.J. Zvolensky Asthma and cigarette smoking: a review of the empirical literature J Asthma 47 2010 345 361
20. F. Reno, V. Rocchetti, M. Migliario, M. Rizzi, and M. Cannas Chronic exposure to cigarette smoke increases matrix metalloproteinases and Filaggrin mRNA expression in oral keratinocytes: role of nicotine stimulation Oral Oncol 47 2011 827 830
21. L.G. Hersoug, L.L. Husemoen, T. Sigsgaard, F. Madsen, and A. Linneberg Indoor exposure to environmental cigarette smoke, but not other inhaled particulates associates with respiratory symptoms and diminished lung function in adults Respirology 15 2010 993 1000
22. M.R. Miller, J. Hankinson, V. Brusasco, F. Burgos, R. Casaburi, and A. Coates Standardisation of spirometry Eur Respir J 26 2005 319 338
23. O.F. Pedersen, N. Naeraa, S. Lyager, C. Hilberg, and L. Larsen A device for evaluation of flow recording equipment Bull Eur Physiopathol Respir 19 1983 515 520
24. P.H. Quanjer, G.J. Tammeling, J.E. Cotes, O.F. Pedersen, R. Peslin, and J.C. Yernault Lung volumes and forced ventilatory flows. Report of the Working Party Standardization of Lung Function Tests, European Community for Steel and Coal. Official Statement of the European Respiratory Society Eur Respir J Suppl 16 1993 5 40
25. American Thoracic Society, European Respiratory Society American Thoracic Society/European Respiratory Society recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005 Am J Respir Crit Care Med 171 2005 912 930
26. A.B. Petersen, P. Gudmann, P. Milvang-Gronager, R. Morkeberg, S. Bogestrand, and A. Linneberg Performance evaluation of a specific IgE assay developed for the ADVIA centaur immunoassay system Clin Biochem 37 2004 882 892
27. J. Pekkanen, J. Sunyer, J.M. Anto, and P. Burney Operational definitions of asthma in studies on its aetiology Eur Respir J 26 2005 28 35
28. J. Sunyer, D. Jarvis, J. Pekkanen, S. Chinn, C. Janson, and B. Leynaert Geographic variations in the effect of atopy on asthma in the European Community Respiratory Health Study J Allergy Clin Immunol 114 2004 1033 1039
29. H.C. Williams, P.G. Burney, R.J. Hay, C.B. Archer, M.J. Shipley, and J.J. Hunter The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis Br J Dermatol 131 1994 383 396
30. H.C. Williams, P.G. Burney, A.C. Pembroke, and R.J. Hay The U.K. Working Party's Diagnostic Criteria for Atopic Dermatitis. III. Independent hospital validation Br J Dermatol 131 1994 406 416
31. A. Linneberg, N.H. Nielsen, T. Menne, F. Madsen, and T. Jorgensen Smoking might be a risk factor for contact allergy J Allergy Clin Immunol 111 2003 980 984
32. J. Eugen-Olsen, O. Andersen, A. Linneberg, S. Ladelund, T.W. Hansen, and A. Langkilde Circulating soluble urokinase plasminogen activator receptor predicts cancer, cardiovascular disease, diabetes and mortality in the general population J Intern Med 268 2010 296 308
33. M. Raymond, and F. Rousset Genepop (Version-1.2) - population-genetics software for exact tests and ecumenicism J Hered 86 1995 248 249
34. F. Rousset GENEPOP'007: a complete re-implementation of the GENEPOP software for Windows and Linux Mol Ecol Resources 8 2008 103 106
35. T.J. Hudson Skin barrier function and allergic risk Nat Genet 38 2006 399 400
36. Z. Wu, B. Hansmann, U. Meyer-Hoffert, R. Glaser, and J.M. Schroder Molecular identification and expression analysis of filaggrin-2, a member of the S100 fused-type protein family PLoS One 4 2009 e5227
37. R.B. Presland, and B.A. Dale Epithelial structural proteins of the skin and oral cavity: function in health and disease Crit Rev Oral Biol Med 11 2000 383 408
38. K. Bonnelykke, C.B. Pipper, R. Tavendale, C.N. Palmer, and H. Bisgaard Filaggrin gene variants and atopic diseases in early childhood assessed longitudinally from birth Pediatr Allergy Immunol 21 2010 954 961
39. A. Linneberg, N.H. Nielsen, F. Madsen, L. Frolund, A. Dirksen, and T. Jorgensen Smoking and the development of allergic sensitization to aeroallergens in adults: a prospective population-based study. The Copenhagen Allergy Study Allergy 56 2001 328 332
40. S. Karrasch, K. Ernst, J. Behr, J. Heinrich, R.M. Huber, and D. Nowak Exhaled nitric oxide and influencing factors in a random population sample Respir Med 105 2011 713 718
41. J. McGrath, J.W. McDonald, and J.K. Macdonald Transdermal nicotine for induction of remission in ulcerative colitis Cochrane Database Syst Rev 4 2004 CD004722
42. S.J. Chanock, T. Manolio, M. Boehnke, E. Boerwinkle, D.J. Hunter, and G. Thomas Replicating genotype-phenotype associations Nature 447 2007 655 660
43. J.N. Hirschhorn, K. Lohmueller, E. Byrne, and K. Hirschhorn A comprehensive review of genetic association studies Genet Med 4 2002 45 61
44. N.D. Berg, A. Linneberg, A. Dirksen, and J. Elberling Prevalence of self-reported symptoms and consequences related to inhalation of airborne chemicals in a Danish general population Int Arch Occup Environ Health 81 2008 881 887