HOXC4 homeoprotein efficiently expands human hematopoietic stem cells and triggers similar molecular alterations as HOXB4

Haematologica

Volumn 97, Issue 2, 2012, Pages 168-178

  Auvray, Céline ^a,b   Delahaye, Andrée ^a,c   Pflumio, Françoise ^d   Haddad, Rima ^e   Amsellem, Sophie ^f   Miri Nezhad, Ayda ^a,b   Broix, Loïc ^a,b   Yacia, Azzedine ^a,b   Bulle, Frédérique ^a,b   Fichelson, Serge ^a,b   Vigon, Isabelle ^a,b  

^a INSTITUT COCHIN   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c UNIVERSITÉ PARIS 13   (France)

^d Universite Paris Sud   (France)

^e Centre National de la Recherche Scientifique   (France)

^f INSTITUT GUSTAVE ROUSSY   (France)

Author keywords

Cell therapy; Hematopoiesis; Hematopoietic stem cell; Stem cell transplantation

Indexed keywords

HEMOPROTEIN; PROTEIN HOXB4; PROTEIN HOXC4; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BPTF GENE; CD34 SELECTION; CEBPB GENE; CELL FATE; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; EGR1 GENE; GATA3 GENE; GENE; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENE TARGETING; HBP1 GENE; HEMATOPOIETIC STEM CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HNRPDL GENE; HNRPK GENE; HOXA9 GENE; HOXB4 GENE; HOXC4 GENE; HUMAN; HUMAN CELL; IKZF1 GENE; IN VITRO STUDY; KLF10 GENE; LYAR GENE; MARKER GENE; MEF2C GENE; MOLECULAR CLONING; MOUSE; NCL GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN SECRETION; RNF10 GENE; RNPS1 GENE; SIGNAL TRANSDUCTION; STEM CELL EXPANSION; STROMA CELL; SUPT16H GENE; SYF2 GENE; TES GENE; TRANSCRIPTION REGULATION; TRIM28 GENE; TSC22D1 GENE; UPREGULATION; ZMYND11 GENE;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; HEK293 CELLS; HEMATOPOIETIC STEM CELLS; HOMEODOMAIN PROTEINS; HUMANS; MICE; MICE, INBRED NOD; MICE, SCID; TRANSCRIPTION FACTORS;

EID: 84856455188     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2011.051235     Document Type: Article

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