Propagation of spinal nociceptive activity in the spatial and temporal domains

Neuroscientist

Volumn 18, Issue 1, 2012, Pages 8-14

  Jongen, Joost L M ^a   Holstege, Jan C ^a  

^a ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

flavoprotein; imaging; nociception; pain; spinal cord

Indexed keywords

FLAVOPROTEIN; NEUROKININ 1 RECEPTOR; NITRATE REDUCTASE (NADH); PROTEIN KINASE C;

ANTINOCICEPTION; ARTICLE; AUTOFLUORESCENCE IMAGING; BLOOD OXYGENATION; BRAIN CORTEX; BRAIN REGION; CHRONIC PAIN; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GLIA CELL; HEMODYNAMICS; HUMAN; HYPERALGESIA; MOTOR NERVE CONDUCTION; NEUROIMAGING; NEUROPATHIC PAIN; NOCICEPTIVE STIMULATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSTSYNAPTIC POTENTIAL; PRIORITY JOURNAL; PSYCHOPHYSIOLOGY; SPINAL CORD DORSAL HORN;

AFFERENT PATHWAYS; ANIMALS; CENTRAL NERVOUS SYSTEM SENSITIZATION; CHRONIC PAIN; NEURALGIA; NEUROIMAGING; NOCICEPTORS; PAIN; RATS; SPINAL CORD; SYNAPTIC TRANSMISSION;

EID: 84856429967     PISSN: 10738584     EISSN: 10894098     Source Type: Journal    
DOI: 10.1177/1073858410391813     Document Type: Article

References (37)

1. Basbaum AI, Bautista DM, Scherrer G, Julius D. Cellular and molecular mechanisms of pain. Cell. 2009 ; 139 (2). 267-84
2. Brieu N, Beaumont E, Dubeau S, Cohen-Adad J, Lesage F. Characterization of the hemodynamic response in the rat lumbar spinal cord using intrinsic optical imaging and laser speckle. J Neurosci Methods. 2010 ; 191 (2). 151-7
3. Coggeshall RE. Fos, nociception and the dorsal horn. Prog Neurobiol. 2005 ; 77 (5). 299-352 (Pubitemid 41815592)
4. Costigan M, Befort K, Karchewski L, Griffin RS, D'Urso D, Allchorne A. Replicate high-density rat genome oligonucleotide microarrays reveal hundreds of regulated genes in the dorsal root ganglion after peripheral nerve injury. BMC Neurosci. 2002 ; 3: 16
5. Craig AD. How do you feel? Interoception: the sense of the physiological condition of the body. Nat Rev Neurosci. 2002 ; 3 (8). 655-66 (Pubitemid 135706673)
6. Devor M, Merrill EG, Wall PD. Dorsal horn cells that respond to stimulation of distant dorsal roots. J Physiol. 1977 ; 270 (2). 519-31 (Pubitemid 8167848)
7. Devor M, Wall PD. Effect of peripheral nerve injury on receptive fields of cells in the cat spinal cord. J Comp Neurol. 1981 ; 199 (2). 277-91 (Pubitemid 11122897)
8. Gao W, Chen G, Reinert KC, Ebner TJ. Cerebellar cortical molecular layer inhibition is organized in parasagittal zones. J Neurosci. 2006 ; 26 (32). 8377-87 (Pubitemid 44309852)
9. Grinvald A, Lieke E, Frostig RD, Gilbert CD, Wiesel TN. Functional architecture of cortex revealed by optical imaging of intrinsic signals. Nature. 1986 ; 324 (6095). 361-4 (Pubitemid 17180109)
10. Hossaini M, Jongen JL, Biesheuvel K, Kuhl D, Holstege JC. Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin. Mol Pain. 2010 ; 6: 43
11. Hudspith MJ, Harrisson S, Smith G, Bountra C, Elliot PJ, Birch PJ. Effect of post-injury NMDA antagonist treatment on long-term Fos expression and hyperalgesia in a model of chronic neuropathic pain. Brain Res. 1999 ; 822 (1-2). 220-7 (Pubitemid 29222845)
12. Hughes DI, Scott DT, Todd AJ, Riddell JS. Lack of evidence for sprouting of Abeta afferents into the superficial laminas of the spinal cord dorsal horn after nerve section. J Neurosci. 2003 ; 23 (29). 9491-9 (Pubitemid 37352049)
13. Ikeda H, Stark J, Fischer H, Wagner M, Drdla R, Jager T. Synaptic amplifier of inflammatory pain in the spinal dorsal horn. Science. 2006 ; 312 (5780). 1659-62 (Pubitemid 43902666)
14. Johannssen HC, Helmchen F. In vivo Ca2+ imaging of dorsal horn neuronal populations in mouse spinal cord. J Physiol. 2010 ; 588: 3397-402
15. Jongen JL, Jaarsma D, Hossaini M, Natarajan D, Haasdijk ED, Holstege JC. Distribution of RET immunoreactivity in the rodent spinal cord and changes after nerve injury. J Comp Neurol. 2007 ; 500 (6). 1136-53 (Pubitemid 46106471)
16. Jongen JL, Pederzani T, Koekkoek SK, Shapiro J, van der Burg J, De Zeeuw CI. Autofluorescent flavoprotein imaging of spinal nociceptive activity. J Neurosci. 2010 ; 30 (11). 4081-7
17. Koerber HR, Mendell LM. Functional specialization of central projections from identified primary afferent fibers. J Neurophysiol. 1988 ; 60 (5). 1597-614
18. Koerber HR, Mirnics K, Brown PB, Mendell LM. Central sprouting and functional plasticity of regenerated primary afferents. J Neurosci. 1994 ; 14 (6). 3655-71 (Pubitemid 24174114)
19. Latremoliere A, Woolf CJ. Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J Pain. 2009 ; 10 (9). 895-926
20. Lewis T Pain. New York: Macmillan ; 1942 :
21. Light AR, Perl ER. Reexamination of the dorsal root projection to the spinal dorsal horn including observations on the differential termination of coarse and fine fibers. J Comp Neurol. 1979 ; 186 (2). 117-31
22. Malmberg AB, Chen C, Tonegawa S, Basbaum AI. Preserved acute pain and reduced neuropathic pain in mice lacking PKCgamma. Science. 1997 ; 278 (5336). 279-83 (Pubitemid 27450873)
23. Mantyh PW, Rogers SD, Honore P, Allen BJ, Ghilardi JR, Li J. Inhibition of hyperalgesia by ablation of lamina I spinal neurons expressing the substance P receptor. Science. 1997 ; 278: 275-9 (Pubitemid 27450872)
24. Melzack R, Wall PD. Pain mechanisms: a new theory. Science. 1965 ; 150 (699). 971-9
25. Neumann S, Braz JM, Skinner K, Llewellyn-Smith IJ, Basbaum AI. Innocuous, not noxious, input activates PKCgamma interneurons of the spinal dorsal horn via myelinated afferent fibers. J Neurosci. 2008 ; 28 (32). 7936-44
26. Price DD, Greenspan JD, Dubner R. Neurons involved in the exteroceptive function of pain. Pain. 2003 ; 106 (3). 215-9 (Pubitemid 37505869)
27. Rexed B. The cytoarchitectonic organization of the spinal cord in the cat. J Comp Neurol. 1952 ; 96 (3). 414-95
28. Ro LS, Li HY, Huang KF, Chen ST. Territorial and extra-territorial distribution of Fos protein in the lumbar spinal dorsal horn neurons in rats with chronic constriction nerve injuries. Brain Res. 2004 ; 1004 (1-2). 177-87
29. Sasaki S, Yazawa I, Miyakawa N, Mochida H, Shinomiya K, Kamino K. Optical imaging of intrinsic signals induced by peripheral nerve stimulation in the in vivo rat spinal cord. Neuroimage. 2002 ; 17 (3). 1240-55 (Pubitemid 35333845)
30. Seal RP, Wang X, Guan Y, Raja SN, Woodbury CJ, Basbaum AI. Injury-induced mechanical hypersensitivity requires C-low threshold mechanoreceptors. Nature. 2009 ; 462 (7273). 651-5
31. Shibuki K, Hishida R, Murakami H, Kudoh M, Kawaguchi T, Watanabe M. Dynamic imaging of somatosensory cortical activity in the rat visualized by flavoprotein autofluorescence. J Physiol. 2003 ; 549 (Pt 3). 919-27 (Pubitemid 36889779)
32. Simone DA, Sorkin LS, Oh U, Chung JM, Owens C, LaMotte RH. Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neurons. J Neurophysiol. 1991 ; 66 (1). 228-46
33. Snider WD, McMahon SB. Tackling pain at the source: new ideas about nociceptors. Neuron. 1998 ; 20 (4). 629-32 (Pubitemid 28199043)
34. Tsuda M, Inoue K, Salter MW. Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci. 2005 ; 28 (2). 101-7 (Pubitemid 40178927)
35. Woolf CJ. Evidence for a central component of post-injury pain hypersensitivity. Nature. 1983 ; 306 (5944). 686-8 (Pubitemid 14201852)
36. Woolf CJ, Shortland P, Coggeshall RE. Peripheral nerve injury triggers central sprouting of myelinated afferents. Nature. 1992 ; 355: 75-8
37. Zhao F, Williams M, Meng X, Welsh DC, Coimbra A, Crown ED. BOLD and blood volume-weighted fMRI of rat lumbar spinal cord during non-noxious and noxious electrical hindpaw stimulation. Neuroimage. 2008 ; 40 (1). 133-47