Novel pathway of centrosome amplification that does not require DNA lesions

Cancer Science

Volumn 103, Issue 2, 2012, Pages 191-196

  Tsuda, Masataka ^a,b,c   Tanaka, Masakazu ^b   Mushiake, Masatoshi ^a,b   Takahashi, Jun ^a   Tanaka, Koji ^a   Watase, Joji ^a,d   Fujisawa, Jun Ichi ^b   Miwa, Masanao ^a  

^a NAGAHAMA INSTITUTE OF BIO SCIENCE AND TECHNOLOGY   (Japan)

^b KANSAI MEDICAL UNIVERSITY   (Japan)

^c KYOTO UNIVERSITY   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

3 AMINOBENZAMIDE; ALKALINE CERAMIDASE; HISTONE H2AX; METHYLNITRONITROSOGUANIDINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE;

ANIMAL CELL; ARTICLE; ATAXIA TELANGIECTASIA; CARCINOGENESIS; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL EXPANSION; CELL VIABILITY; CENTROSOME; CHO CELL; COMET ASSAY; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; FIBROBLAST; MUTAGENICITY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ANIMALS; AZULENES; BENZAMIDES; BENZODIAZEPINES; CELL CYCLE; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL PROLIFERATION; CENTROSOME; CHO CELLS; CRICETINAE; DNA; DNA DAMAGE; DNA-BINDING PROTEINS; HISTONES; METHYLNITRONITROSOGUANIDINE; MITOSIS; MUTAGENESIS; POLY ADENOSINE DIPHOSPHATE RIBOSE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 84856426047     PISSN: 13479032     EISSN: 13497006     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2011.02152.x     Document Type: Article

References (36)

1. Bornens M. Centrosome composition and microtubule anchoring mechanisms. Curr Opin Cell Biol 2002; 14: 25-34.
2. Robbins E, Jentzsch G, Micali A. The centriole cycle in synchronized HeLa cells. J Cell Biol 1968; 36: 329-39.
3. Meraldi P, Nigg EA. The centrosome cycle. FEBS Lett 2002; 521: 9-13.
4. Nigg EA. Centrosome aberrations: cause or consequence of cancer progression? Nat Rev Cancer 2002; 2: 815-25.
5. Rajagopalan H, Lengauer C. Aneuploidy and cancer. Nature 2004; 432: 338-41.
6. Sato N, Mizumoto K, Nakamura M, Tanaka M. Radiation-induced centrosome overduplication and multiple mitotic spindles in human tumor cells. Exp Cell Res 2000; 255: 321-6.
7. Bourke E, Dodson H, Merdes A et al. DNA damage induces Chk1-dependent centrosome amplification. EMBO Rep 2007; 8: 603-9.
8. Sugihara E, Kanai M, Saito S et al. Suppression of centrosome amplification after DNA damage depends on p27 accumulation. Cancer Res 2006; 66: 4020-9.
9. Sugimura T, Nagao M, Okada Y. Carcinogenic action of N-Methyl-N'-nitro-N-nitrosoguanidine. Nature 1966; 210: 962-3.
10. Ogata N, Ueda K, Kagamiyama H, Hayaishi O. ADP-ribosylation of histone H1. Identification of glutamic acid residue 2. 14. and the COOH-terminal lysine residue as modification sites. J Biol Chem 1980; 255: 7616-20.
11. Suzuki H, Quesada P, Farina B, Leone E. In vitro poly(ADP-ribosyl)ation of seminal ribonuclease. J Biol Chem 1986; 261: 6048-55.
12. Miwa M, Masutani M. PolyADP-ribosylation and cancer. Cancer Sci 2007; 98: 1527-35.
13. Altmeyer M, Messner S, Hassa PO, Fey M, Hottiger MO. Molecular mechanism of poly(ADP-ribosyl)ation by PARP1 and identification of lysine residues as ADP-ribose acceptor sites. Nucleic Acids Res 2009; 37: 3723-38.
14. Benjamin RC, Gill DM. Poly(ADP-ribose) synthesis in vitro programmed by damaged DNA. A comparison of DNA molecules containing different types of strand breaks. J Biol Chem 1980; 255: 10502-8.
15. Ikejima M, Noguchi S, Yamashita R et al. The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and the consequent enzyme activation. Other structures recognize intact DNA. J Biol Chem 1990; 265: 21907-13.
16. Kanai M, Tong WM, Sugihara E, Wang ZQ, Fukasawa K, Miwa M. Involvement of poly(ADP-Ribose) polymerase 1 and poly(ADP-Ribosyl)ation in regulation of centrosome function. Mol Cell Biol 2003; 23: 2451-62.
17. Kanai M, Tong WM, Wang ZQ, Miwa M. Haploinsufficiency of poly(ADP-ribose) polymerase-1-mediated poly(ADP-ribosyl)ation for centrosome duplication. Biochem Biophys Res Commun 2007; 359: 426-30.
18. Althaus FR, Kleczkowska HE, Malanga M et al. Poly ADP-ribosylation: a DNA break signal mechanism. Mol Cell Biochem 1999; 193: 5-11.
19. Griffin RJ, Pemberton LC, Rhodes D et al. Novel potent inhibitors of the DNA repair enzyme poly(ADP-ribose)polymerase (PARP). Anticancer Drug Des 1995; 10: 507-14.
20. Curtin NJ, Wang LZ, Yiakouvaki A et al. Novel poly(ADP-ribose) polymerase-1 inhibitor, AG14361, restores sensitivity to temozolomide in mismatch repair-deficient cells. Clin Cancer Res 2004; 10: 881-9.
21. Oda Y, Yamazaki H, Watanabe M, Nohmi T, Shimada T. Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic acromatic amines by Salmonella typhimurium strain NM2009 processing high O-acetyltransferase activity. Mutat Res 1995; 334: 145-56.
22. Tayama S, Nakagawa Y, Tayama K. Genotoxic effects of environmental estrogen-like compounds in CHO-K1 cells. Mutat Res 2008; 649: 114-25.
23. Wang J, Bian C, Li J, Couch FJ, Wu K, Zhao RC. Poly(ADP-ribose) polymerase-1 down-regulates BRCA2 expression through the BRCA2 promoter. J Biol Chem 2008; 283: 36249-56.
24. Purnell MR, Whish WJ. Novel inhibitors of poly(ADP-ribose) synthetase. Biochem J 1980; 185: 775-7.
25. Dash BC, El-Deiry WS. Cell cycle checkpoint control mechanisms that can be disrupted in cancer. Methods Mol Biol 2004; 280: 99-161.
26. Ismail IH, Wadhra TI, Hammarsten O. An optimized method for detecting gamma-H2AX in blood cells reveals a significant interindividual variation in the gamma-H2AX response among humans. Nucleic Acids Res 2007; 35: e36.
27. Yu Y, Zhu W, Diao H, Zhou C, Chen FF, Yang J. A comparative study of using comet assay and gammaH2AX foci formation in the detection of N-methyl-N'-nitro-N-nitrosoguanidine-induced DNA damage. Toxicol In Vitro 2006; 20: 959-65.
28. Zhang S, Hemmerich P, Grosse F. Centrosomal localization of DNA damage checkpoint proteins. J Cell Biochem 2007; 101: 451-65.
29. Shimada M, Kobayashi J, Hirayama R, Komatsu K. Differential role of repair proteins, BRCA1/NBS1 and Ku70/DNA-PKcs, in radiation-induced centrosome overduplication. Cancer Sci 2010; 101: 2531-7.
30. Hu T, Miller CM, Ridder GM, Aardema MJ. Characterization of p53 in Chinese hamster cell lines CHO-K1, CHO-WBL, and CHL: implications for genotoxicity testing. Mutat Res 1999; 426: 51-62.
31. Katsura M, Tsuruga T, Date O et al. The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction. Nucleic Acids Res 2009; 37: 3959-68.
32. Suzuki M, Suzuki K, Kodama S, Watanabe M. Phosphorylated histone H2AX foci persist on rejoined mitotic chromosomes in normal human diploid cells exposed to ionizing radiation. Radiat Res 2006; 165: 269-76.
33. Dodson H, Bourke E, Jeffers LJ et al. Centrosome amplification induced by DNA damage occurs during a prolonged G2 phase and involves ATM. EMBO J 2004; 23: 3864-73.
34. Schwartz JL, Morgan WF, Brown-Lindquist P, Afzal V, Weichselbaum RR, Wolff S. Comutagenic effects of 3-aminobenzamide in Chinese hamster ovary cells. Cancer Res 1985; 45: 1556-9.
35. Eliopoulos P, Mourelatos D, Dozi-Vassiliades J. Comparative study on Salmonella mutagenicity and on cytogenetic and antineoplastic effects induced by cyclophosphamide and 3-aminobenzamide in cells of three transplantable tumours in vivo. Mutat Res 1995; 342: 141-6.
36. Soutoglou E, Misteli T. Activation of the cellular DNA damage response in the absence of DNA lesions. Science 2008; 320: 1507-10.