Penta-O-galloyl-β-d-glucose attenuates cisplatin-induced nephrotoxicity via reactive oxygen species reduction in renal epithelial cells and enhances antitumor activity in Caki-2 renal cancer cells

Toxicology in Vitro

Volumn 26, Issue 2, 2012, Pages 206-214

  Ryu, Ho Geon ^a   Jeong, Soo Jin ^a   Kwon, Hee Young ^a   Lee, Hyo Jung ^a   Lee, Eun Ok ^a   Lee, Min Ho ^a   Choi, Seung Hoon ^a   Ahn, Kyoo Seok ^a   Kim, Sung Hoon ^a  

^a Kyung Hee University   (South Korea)

Author keywords

Cisplatin; Normal renal cells; PGG; Protection; Renal cancer cells; Sensitization

Indexed keywords

ASCORBIC ACID; BETA ACTIN; CASPASE 3; CISPLATIN; CYTOCHROME C; GLUCOSE PENTAGALLATE; HYDROGEN PEROXIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL ASSAY; CELL COUNT; CELL CYCLE G1 PHASE; CELL PROTECTION; CELL VIABILITY; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME RELEASE; EPITHELIUM CELL; HUMAN; HUMAN CELL; INHIBITION KINETICS; KIDNEY EPITHELIUM; NEPHROTOXICITY; NICK END LABELING; PROTEIN EXPRESSION; UPREGULATION;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; DRUG THERAPY, COMBINATION; EPITHELIAL CELLS; HUMANS; HYDROLYZABLE TANNINS; KIDNEY; PROTECTIVE AGENTS; REACTIVE OXYGEN SPECIES;

EID: 84856411358     PISSN: 08872333     EISSN: 18793177     Source Type: Journal    
DOI: 10.1016/j.tiv.2011.11.012     Document Type: Article

References (43)

1. Chai Y., Lee H.J., Shaik A.A., Nkhata K., Xing C., Zhang J., Jeong S.J., Kim S.H., Lu J. Penta-O-galloyl-beta-d-glucose induces G1 arrest and DNA replicative S-phase arrest independently of P21 cyclin-dependent kinase inhibitor 1A, P27 cyclin-dependent kinase inhibitor 1B and P53 in human breast cancer cells and is orally active against triple-negative xenograft growth. Breast Cancer Res. 2010, 12:R67.
2. Chen W.J., Chang C.Y., Lin J.K. Induction of G1 phase arrest in MCF human breast cancer cells by pentagalloylglucose through the down-regulation of CDK4 and CDK2 activities and up-regulation of the CDK inhibitors p27(Kip) and p21(Cip). Biochem. Pharmacol. 2003, 65:1777-1785.
3. Chou T.C. Drug combination studies and their synergy quantification using the Chou-Talalay method. Cancer Res. 2010, 70:440-446.
4. Dorrenhaus A., Muller J.I., Golka K., Jedrusik P., Schulze H., Follmann W. Cultures of exfoliated epithelial cells from different locations of the human urinary tract and the renal tubular system. Arch. Toxicol. 2000, 74:618-626.
5. Greene E.L., Farell G., Yu S., Matthews T., Kumar V., Lieske J.C. Renal cell adaptation to oxalate. Urol. Res. 2005, 33:340-348.
6. Herrmann M., Lorenz H.M., Voll R., Grunke M., Woith W., Kalden J.R. A rapid and simple method for the isolation of apoptotic DNA fragments. Nucleic Acids Res. 1994, 22:5506-5507.
7. Hofmann A.S., Gross G.G. Biosynthesis of gallotannins: formation of polygalloylglucoses by enzymatic acylation of 1, 2, 3, 4, 6-penta-O-galloylglucose. Arch. Biochem. Biophys. 1990, 283:530-532.
8. Hu H., Lee H.J., Jiang C., Zhang J., Wang L., Zhao Y., Xiang Q., Lee E.O., Kim S.H., Lu J. Penta-1, 2, 3, 4, 6-O-galloyl-beta-d-glucose induces p53 and inhibits STAT3 in prostate cancer cells in vitro and suppresses prostate xenograft tumor growth in vivo. Mol. Cancer Ther. 2008, 7:2681-2691.
9. Huh J.E., Lee E.O., Kim M.S., Kang K.S., Kim C.H., Cha B.C., Surh Y.J., Kim S.H. Penta-O-galloyl-beta-d-glucose suppresses tumor growth via inhibition of angiogenesis and stimulation of apoptosis: roles of cyclooxygenase-2 and mitogen-activated protein kinase pathways. Carcinogenesis 2005, 26:1436-1445.
10. Kang S.H., Lee H.J., Jeong S.J., Kwon H.Y., Kim J.H., Yun S.M., Kim J.H., Lee H.J., Lee E.O., Ahn K.S., Ahn K.S., Kim S.H. Protective effect of Bojungbangdocktang on cisplatin-induced cytotoxicity and apoptosis in MCF-10A breast endothelial cells. Environ. Toxicol. Pharm. 2009, 28:430-438.
11. Khan S.A., Priyamvada S., Khan W., Khan S., Farooq N., Yusufi A.N. Studies on the protective effect of green tea against cisplatin induced nephrotoxicity. Pharmacol. Res. 2009, 60:382-391.
12. Kim J.H., Jeong S.J., Kwon H.Y., Park S.Y., Lee H.J., Lieske J.C., Kim S.H. Decursin prevents cisplatin-induced apoptosis via the enhancement of antioxidant enzymes in human renal epithelial cells. Biol. Pharm. Bull. 2010, 33:1279-1284.
13. Kitagawa S., Nabekura T., Nakamura Y., Takahashi T., Kashiwada Y. Inhibition of P-glycoprotein function by tannic acid and pentagalloylglucose. J. Pharm. Pharmacol. 2007, 59:965-969.
14. Koh W., Ahn K.S., Jeong S.J., Lee H.J., Kim M., Lee H.J., Lee E.O., Kim S.H. Reactive oxygen species are involved in sulforaphane-induced STAT3 inactivation and apoptosis in DU145 prostate cancer cells. Chin. Sci. Bull. 2010, 34:1828-1834.
15. Kroemer G., Zamzami N., Susin S.A. Mitochondrial control of apoptosis. Immunol. Today 1997, 18:44-51.
16. Kuo P.T., Lin T.P., Liu L.C., Huang C.H., Lin J.K., Kao J.Y., Way T.D. Penta-O-galloyl-beta-d-glucose suppresses prostate cancer bone metastasis by transcriptionally repressing EGF-induced MMP-9 expression. J. Agric. Food. Chem. 2009, 57:3331-3339.
17. Lajolo P.P., de Camargo B., del Giglio A. Omission of day 2 of antiemetic medications is a cost saving strategy for improving chemotherapy-induced nausea and vomiting control: results of a randomized phase III trial. Am. J. Clin. Oncol. 2009, 32:23-26.
18. Lee S.J., Lee H.M., Ji S.T., Lee S.R., Mar W., Gho Y.S. 1,2,3,4,6-Penta-O-galloyl-beta-d-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor. Cancer Lett. 2004, 208:89-94.
19. Lee C.K., Park K.K., Hwang J.K., Lee S.K., Chung W.Y. The extract of Prunus persica flesh (PPFE) attenuates chemotherapy-induced hepatotoxicity in mice. Phytother. Res. 2008, 22:223-227.
20. Lee C.K., Park K.K., Hwang J.K., Lee S.K., Chung W.Y. Extract of Prunus persica flesh (PPFE) improves chemotherapeutic efficacy and protects against nephrotoxicity in cisplatin-treated mice. Phytother Res 2009, 23:999-1005.
21. Lee J.H., Lee H.J., Choi W.C., Yoon S.W., Ko S.G., Ahn K.S., Choi S.H., Lieske J.C., Kim S.H. Rhus verniciflua Stokes prevents cisplatin-induced cytotoxicity and reactive oxygen species production in MDCK-I renal cells and intact mice. Phytomedicine 2009, 16:188-197.
22. Lee H.J., Kim S.A., Jeong S.J., Han I., Jung J.H., Lee E.O., Zhu S., Chen C.Y., Kim S.H. Paeonol oxime inhibits bFGF-induced angiogenesis and reduces VEGF levels in fibrosarcoma cells. PLoS ONE 2010, 5:e12358.
23. Lee H.J., Jeong S.J., Lee E.O., Bae H., Lieske J.C., Kim S.H. 1,2,3,4,6-Penta-O-galloyl-beta-d-glucose reduces renal crystallization and oxidative stress in a hyperoxaluric rat model. Kidney Int. 2011, 79:538-545.
24. Lee H.J., Seo N.J., Jeong S.J., Park Y., Jung D.B., Koh W., Lee E.O., Ahn K.S., Lu J., Kim S.H. Oral administration of penta-O-galloyl-{beta}-d-glucose suppresses triple-negative breast cancer xenograft growth and metastasis in strong association with JAK1-STAT3 inhibition. Carcinogenesis 2011, 32:804-811.
25. Lim E.S., Rhee Y.H., Park M.K., Shim B.S., Ahn K.S., Kang H., Yoo H.S., Kim S.H. DMNQ S-64 induces apoptosis via caspase activation and cyclooxygenase-2 inhibition in human nonsmall lung cancer cells. Ann. N. Y. Acad. Sci. 2007, 1095:7-18.
26. Maines M.D. Effect of cis-platinum on heme, drug, and steroid metabolism pathways: possible involvement in nephrotoxicity and infertility. Crit. Rev. Toxicol. 1990, 21:1-20.
27. Masubuchi Y., Horie T. Toxicological significance of mechanism-based inactivation of cytochrome p450 enzymes by drugs. Crit. Rev. Toxicol. 2007, 37:389-412.
28. Molitoris B.A., Dagher P.C., Sandoval R.M., Campos S.B., Ashush H., Fridman E., Brafman A., Faerman A., Atkinson S.J., Thompson J.D., Kalinski H., Skaliter R., Erlich S., Feinstein E. SiRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury. J. Am. Soc. Nephrol. 2009, 20:1754-1764.
29. Oh G.S., Pae H.O., Oh H., Hong S.G., Kim I.K., Chai K.Y., Yun Y.G., Kwon T.O., Chung H.T. In vitro anti-proliferative effect of 1, 2, 3, 4, 6-penta-O-galloyl-beta-d-glucose on human hepatocellular carcinoma cell line, SK-HEP-1 cells. Cancer Lett. 2001, 174:17-24.
30. Pan M.H., Lin J.H., Lin-Shiau S.Y., Lin J.K. Induction of apoptosis by penta-O-galloyl-beta-d-glucose through activation of caspase-3 in human leukemia HL-60 cells. Eur. J. Pharmacol. 1999, 381:171-183.
31. Park K.Y., Lee H.J., Jeong S.J., Kim H.S., Kim S.H., Lim S., Kim H.C., Lu J. 1,2,3,4,6-Penta-O-galloly-beta-d-glucose suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and signaling in LNCaP prostate cancer cells. Biol. Pharm. Bull. 2010, 33:1835-1840.
32. Patton T.F., Repta A.J., Sternson L.A., Belt R.J. Pharmacokinetics of intact cisplatin in plasma. Infusion versus bolus dosing. Int. J. Pharmacol. 1982, 10:77-85.
33. Pillai T.G., John M., Sara Thomas G. Prevention of cisplatin induced nephrotoxicity by terpenes isolated from Ganoderma lucidum occurring in Southern Parts of India. Exp. Toxicol. Pathol. 2011, 63:157-160.
34. Polyak K., Xia Y., Zweier J.L., Kinzler K.W., Vogelstein B. A model for p53-induced apoptosis. Nature 1997, 389:300-305.
35. Raffo A.J., Kim A.L., Fine R.L. Formation of nuclear Bax/p53 complexes is associated with chemotherapy induced apoptosis. Oncogene 2000, 19:6216-6228.
36. Saleh S., Ain-Shoka A.A., El-Demerdash E., Khalef M.M. Protective effects of the angiotensin II receptor blocker losartan on cisplatin-induced kidney injury. Chemotherapy 2009, 55:399-406.
37. Schmitt C.A., Fridman J.S., Yang M., Baranov E., Hoffman R.M., Lowe S.W. Dissecting p53 tumor suppressor functions in vivo. Cancer Cell 2002, 1:289-298.
38. Schuler M., Bossy-Wetzel E., Goldstein J.C., Fitzgerald P., Green D.R. P53 induces apoptosis by caspase activation through mitochondrial cytochrome c release. J. Biol. Chem. 2000, 275:7337-7342.
39. Shaulian E., Karin M. AP-1 as a regulator of cell life and death. Nat. Cell Biol. 2002, 4:E131-136.
40. Shaulian E., Schreiber M., Piu F., Beeche M., Wagner E.F., Karin M. The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest. Cell 2000, 103:897-907.
41. Timmer-Bosscha H., Mulder N.H., de Vries E.G. Modulation of cis-diamminedichloroplatinum(II) resistance. a review. Br. J. Cancer 1992, 66:227-238.
42. Turk G., Ceribasi A.O., Sahna E., Atessahin A. Lycopene and ellagic acid prevent testicular apoptosis induced by cisplatin. Phytomedicine 2011, 18:356-361.
43. Zhang J., Li L., Kim S.H., Hagerman A.E., Lu J. Anti-cancer, anti-diabetic and other pharmacologic and biological activities of penta-galloyl-glucose. Pharm. Res. 2009, 26:2066-2080.