Electroconvulsive seizures stimulate the vegf pathway via mTORC1

Synapse

Volumn 66, Issue 4, 2012, Pages 340-345

  Elfving, Betina ^a   Wegener, Gregers ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

ECS; MTOR; Rat brain; Real time qPCR; VEGF

Indexed keywords

MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DEPRESSION; DOWN REGULATION; ELECTROCONVULSIVE THERAPY; FRONTAL CORTEX; HIPPOCAMPUS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SEIZURE; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ELECTROSHOCK; GENE EXPRESSION PROFILING; MALE; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TOR SERINE-THREONINE KINASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84856384307     PISSN: 08874476     EISSN: 10982396     Source Type: Journal    
DOI: 10.1002/syn.21518     Document Type: Article

References (33)

1. Altar CA, Laeng P, Jurata LW, Brockman JA, Lemire A, Bullard J, Bukhman YV, Young TA, Charles V, Palfreyman MG. 2004. Electroconvulsive seizures regulate gene expression of distinct neurotrophic signaling pathways. J Neurosci 24: 2667-2677.
2. Anderson L, Seilhamer J. 1997. A comparison of selected mRNA and protein abundances in human liver. Electrophoresis 18: 533-537.
3. Andersen CL, Jensen JL, Ørntoft TF. 2004. Normalization of real-time quantitative reverse transcription-PCR data: A model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets. Cancer Res 64: 5245-5250.
4. Bonefeld BE, Elfving B, Wegener G. 2008. Reference genes for normalization: A study of rat brain tissue. Synapse 62: 302-309.
5. Dormond O, Contreras AG, Meijer E, Datta D, Flynn E, Pal S, Briscoe DM. 2008. CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo. J Immunol 181: 8088-8095.
6. Drevets WC. 2007. Orbitofrontal cortex function and structure in depression. Ann NY Acad Sci 1121: 499-527.
7. Elfving B, Bonefeld BE, Rosenberg R, Wegener G. 2008. Differential expression of synaptic vesicle proteins after repeated electroconvulsive seizures in rat frontal cortex and hippocampus. Synapse 62: 662-670.
8. Ferrara N, Gerber HP, LeCouter J. 2003. The biology of VEGF and its receptors. Nat Med 9: 669-676.
9. Franco-Bronson K. 1996. The management of treatment-resistant depression in the medically ill. Psychiatr Clin North Am 19: 329-350.
10. Fujiki M, Abe E, Nagai Y, Shiqi K, Kubo T, Ishii K, Abe T, Kobayashi H. 2010. Electroconvulsive seizure-induced VEGF is correlated with neuroprotective effects against cerebral infarction: Involvement of the phosphatidylinositol-3 kinase/Akt pathway. Exp Neurol 225: 377-383.
11. Gabhann FM, Popel AS. 2005. Differential binding of VEGF isoforms to VEGF receptor 2 in the presence of neuropilin-1: A computational model. Am J Physiol Heart Circ Physiol 288: H2851-H2860.
12. Girgenti MJ, Hunsberger J, Duman CH, Sathyanesan M, Terwilliger R, Newton SS. 2009. Erythropoietin induction by electroconvulsive seizure, gene regulation, and antidepressant-like behavioral effects. Biol Psychiatry 66: 267-274.
13. Jaworski J, Sheng M. 2006. The growing role of mTOR in neuronal development and plasticity. Mol Neurobiol 34: 205-219.
14. Jernigan CS, Goswami DB, Austin MC, Iyo AH, Chandran A, Stockmeier CA, Karolewicz B. 2011. The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 35: 1774-1779.
15. Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. 2002. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110: 163-175.
16. Kim DH, Sarbassov DD, Ali SM, Latek RR, Guntur KV, Erdjument-Bromage H, Tempst P, Sabatini DM. 2003. GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. Mol Cell 11: 895-904.
17. Li N, Lee B, Liu R-J, Banasr M, Dwyer JM, Iwata M, Li X-Y, Aghajanian G, Duman RS. 2010. mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. Science 329: 959-964.
18. Madsen TM, Treschow A, Bengzon J, Bolwig TG, Lindvall O, Tingström A. 2000. Increased neurogenesis in a model of electroconvulsive therapy. Biol Psychiatry 47: 1043-1049.
19. Maletic V, Robinson M, Oakes T, Iyengar S, Ball SG, Russell J. 2007. Neurobiology of depression: an integrated view of key findings. Int J Clin Pract 61: 2030-2040.
20. Merkl A, Heuser I, Bajbouj M. 2009. Antidepressant electroconvulsive therapy: Mechanism of action, recent advances and limitations. Exp Neurol 219: 20-36.
21. Müller HK, Wegener G, Popoli M, Elfving B. 2011. Differential expression of synaptic proteins after chronic restraint stress in rat prefrontal cortex and hippocampus. Brain Res 1385: 26-37.
22. Nakamura K, Tan F, Li Z, Thiele CJ. 2011. NGF activation of TrkA induces vascular endothelial growth factor expression via induction of hypoxia-inducible factor-1alpha. Mol Cell Neurosci 46: 498-506.
23. Newton SS, Collier EF, Hunsberger J, Adams D, Terwilliger R, Selvanayagam E, Duman RS. 2003. Gene profile of electroconvulsive seizures: Induction of neurotrophic and angiogenic factors. J Neurosci 23: 10841-10851.
24. Pradet-Balade B, Boulme F, Beug H, Mullner EW, Garcia-Sanz JA. 2001. Translation control: bridging the gap between genomics and proteomics? Trends Biochem Sci 26: 225-229.
25. Russell RC, Fang C, Guan KL. 2011. An emerging role for TOR signaling in mammalian tissue and stem cell physiology. Development 138: 3343-3356.
26. Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. 2004. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 14: 1296-1302.
27. Sarbassov DD, Ali SM, Sabatini DM. 2005. Growing roles for the mTOR pathway. Curr Opin Cell Biol 17: 596-603.
28. Scott BW, Wojtowicz JM, Burnham WM. 2000. Neurogenesis in the dentate gyrus of the rat following electroconvulsive shock seizures. Exp Neurol 165: 231-236.
29. Segi-Nishida E, Warner-Schmidt JL, Duman RS. 2008. Electroconvulsive seizure and VEGF increase the proliferation of neural stem-like cells in rat hippocampus. Proc Natl Acad Sci USA 105: 11352-11357.
30. Shelton RC, Osuntokun O, Heinloth AN, Corya SA. 2010. Therapeutic options for treatment-resistant depression. CNS Drugs 24: 131-161.
31. Tian Q, Stepaniants SB, Mao M, Weng L, Feetham MC, Doyle MJ, Yi EC, Dai H, Thorsson V, Eng J, Goodlett D, Berger JP, Gunter B, Linseley PS, Stoughton RB, Aebersold R, Collins SJ, Hanlon WA, Hood LE. 2004. Integrated genomic and proteomic analyses of gene expression in Mammalian cells. Mol Cell Proteomics 3: 960-969.
32. Warner-Schmidt JL, Duman RS. 2007. VEGF is an essential mediator of the neurogenic and behavioral actions of antidepressants. Proc Natl Acad Sci USA 104: 4647-4652.
33. Zarate CAJr, Singh JB, Carlson PJ, Brutsche NE, Ameli R, Luckenbaugh DA, Charney DS, Manji HK. 2006. A randomized trial of an N-methyl-D-aspartate antagonist in treatment-resistant major depression. Arch Gen Psychiatry 63:856-864.