Separation of clavulanic acid from fermented broth of amino acids by an aqueous two-phase system and ion-exchange adsorption

New Biotechnology

Volumn 29, Issue 3, 2012, Pages 428-431

  da Silva, Clovis Sacardo ^a   Cuel, Maressa Fabiano ^a   Barreto, Verônica Orlandin ^a   Kwong, Wu Hong ^a   Hokka, Carlos O ^a   Barboza, M ^a,b  

^a FEDERAL UNIVERSITY OF SÃO CARLOS   (Brazil)

^b FEDERAL UNIVERSITY OF TRIÂNGULO MINEIRO   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS TWO PHASE SYSTEM; CLAVULANIC ACID; CONCENTRATION FACTORS; ION-EXCHANGE ADSORPTION; LACTAMASES; LOW MOLECULAR WEIGHT; PARTIAL PURIFICATION; POTASSIUM PHOSPHATE; THERAPEUTIC TREATMENTS;

ADSORPTION; CARBOXYLIC ACIDS; GLYCOLS; ION EXCHANGE; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; PURIFICATION; REMOVAL; SOLVENT EXTRACTION;

AMINO ACIDS;

AMINO ACID; CLAVULANIC ACID; HISTIDINE; LYSINE; MACROGOL; POTASSIUM DIHYDROGEN PHOSPHATE; PROLINE; TYROSINE;

ADSORPTION; ANIMAL EXPERIMENT; AQUEOUS SOLUTION; AQUEOUS TWO PHASE SYSTEM; ARTICLE; BATCH FERMENTATION; BROTH DILUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG IMPURITY; DRUG ISOLATION; DRUG PURIFICATION; DRUG SOLUBILITY; EXTRACTION; ION EXCHANGE CHROMATOGRAPHY; MOLECULAR WEIGHT; NONHUMAN; PRIORITY JOURNAL; STREPTOMYCES CLAVULIGERUS;

ADSORPTION; AMINO ACIDS; CLAVULANIC ACID; CULTURE MEDIA; ION EXCHANGE; STREPTOMYCES;

EID: 84856380240     PISSN: 18716784     EISSN: 18764347     Source Type: Journal    
DOI: 10.1016/j.nbt.2011.05.012     Document Type: Article

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